Dottie Yu
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View article: A rigorous benchmarking of alignment-based HLA typing algorithms for RNA-seq data
A rigorous benchmarking of alignment-based HLA typing algorithms for RNA-seq data Open
Accurate identification of human leukocyte antigen (HLA) alleles is essential for various clinical and research applications, such as transplant matching and drug sensitivities. Recent advances in RNA-seq technology have made it possible t…
View article: Parameterized Computational Framework for the Description and Design of Genetic Circuits of Morphogenesis Based on Contact-Dependent Signaling and Changes in Cell–Cell Adhesion
Parameterized Computational Framework for the Description and Design of Genetic Circuits of Morphogenesis Based on Contact-Dependent Signaling and Changes in Cell–Cell Adhesion Open
Synthetic development is a nascent field of research that uses the tools of synthetic biology to design genetic programs directing cellular patterning and morphogenesis in higher eukaryotic cells, such as mammalian cells. One specific exam…
View article: Rigorous Benchmarking of HLA Callers for RNA Sequencing Data
Rigorous Benchmarking of HLA Callers for RNA Sequencing Data Open
Although precise identification of the human leukocyte antigen (HLA) allele is crucial for various clinical and research applications, HLA typing remains challenging due to high polymorphism of the HLA loci. However, with Next-Generation S…
View article: The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus
The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus Open
Recent advances in high-throughput sequencing technologies have made it possible to collect and share a massive amount of omics data, along with its associated metadata. Enhancing metadata availability is critical to ensure data reusabilit…
View article: A parametrized computational framework for description and design of genetic circuits of morphogenesis based on contact-dependent signaling and changes in cell-cell adhesion
A parametrized computational framework for description and design of genetic circuits of morphogenesis based on contact-dependent signaling and changes in cell-cell adhesion Open
Synthetic development is a nascent field of research that uses the tools of synthetic biology to design genetic programs directing cellular patterning and morphogenesis in higher eukaryotic cells, such as mammalian cells. One specific exam…