Explanipedia

Infective endocarditis: it takes a team Open

Lawrence Lau, Larry M. Baddour, Núria Fernández-Hidalgo, Thomas D. Brothers, William Kong , et al. · 2025

Infective endocarditis (IE) is a relatively rare but life-threatening systemic infection, which remains associated with high morbidity and mortality. The epidemiology of IE has shifted to involve an increasing numbers of older patients wit…

Multiple arterial grafting: are women being left behind? Open

Yuan Qiu, Fraser D. Rubens · 2024

Multiple arterial grafting (MAG) has been evidenced to likely improve long-term mortality and morbidity outcomes compared with single arterial grafting during coronary artery bypass grafting (CABG), with current guidelines recommending its…

Commentary: Muddying the waters: Limitations of secondary subgroup analyses of randomized controlled trials Open

Yuan Qiu, Carl van Walraven, Fraser D. Rubens · 2024

Optimal timing of surgical revascularization in patients with acute myocardial infarction Open

Amin Zahrai, Kenza Rahmouni, Fraser D. Rubens · 2023

Acute myocardial infarction (AMI) is the leading cause of cardiovascular mortality in developed countries. While primary percutaneous coronary intervention is the gold-standard first-line therapy for initial revascularization of a culprit …

Edge-to-edge with partial band mitral valve repair compared to replacement and undersized restrictive annuloplasty for ischemic mitral regurgitation Open

Alex Nantsios, Aryan Ahmadvand, Ian G. Burwash, Vincent Chan, Ming Guo , et al. · 2023

Influence of preoperative frailty on quality of life after cardiac surgery: A systematic review and meta‐analysis Open

Christophe A. Fehlmann, Kathryn Bezzina, Rosetta Mazzola, Sarah Visintini, Ming Hao Guo , et al. · 2023

Background Frailty has emerged as an important prognostic marker of increased mortality after cardiac surgery, but its association with quality of life (QoL) and patient‐centered outcomes is not fully understood. We sought to evaluate the …

Table of Contents Open

Jiabo Shen, L. L. Jiang, Hao Wu, Xiaojie Cai, Shanshan Zhuo , et al. · 2023

Population Study of Sex-Based Outcomes After Surgical Aortic Valve Replacement Open

Fraser D. Rubens, Anna E. Clarke, Douglas S. Lee, George A. Wells, Louise Y. Sun · 2022

Commentary: Can in vitro valve testing reliably predict clinical outcomes? Open

Hugo M.N. Issa, Fraser D. Rubens · 2022

Central MessageNew generations of aortic valve protheses should always aim at better clinical outcomes, whether physics, hemodynamic, or other parameters also mirror those changes.See Article page 43. New generations of aortic valve prothe…

Influence of preoperative frailty on quality of life after cardiac surgery: Protocol for a systematic review and meta-analysis Open

Kathryn Bezzina, Christophe A. Fehlmann, Ming Hao Guo, Sarah Visintini, Fraser D. Rubens , et al. · 2022

Background Frailty has emerged as an important prognostic marker of adverse outcomes after cardiac surgery, but evidence regarding its ability to predict quality of life after cardiac surgery is currently lacking. Whether frail patients de…

Reply: Rose-colored glasses Open

Fraser D. Rubens · 2021

Commentary: Is this a case in which we know what we don't know what we don't know? Open

Alex Nantsios, Fraser D. Rubens · 2021

Commentary: Good things come to those who wait Open

Thin Xuan Vo, Fraser D. Rubens · 2021

Reply: Implications of innovations on clinical outcomes Open

Fraser D. Rubens · 2021

Commentary: One cannot fix what one cannot see Open

Kenza Rahmouni, Fraser D. Rubens · 2021

Commentary: The coronary Gordian knot Open

Kenza Rahmouni, Fraser D. Rubens · 2021

Balancing patient-centered care and evidence-based medicine in patients needing coronary revascularization Open

Fraser D. Rubens, Alice Virani, Megan Coylewright, Janarthanan Sathananthan, David Wood · 2021

Skin cancer at median sternotomy scar Open

Elsayed Elmistekawy, Vidhya Nair, Fraser D. Rubens · 2021

Commentary: Never let semantics get in the way of a good idea Open

Ming Hao Guo, Fraser D. Rubens · 2021

Central MessageThe addition of cannulas for patients on extracorporeal membrane oxygenation (ECMO) should be called "extended" ECMO and should be in the armamentarium of heart failure surgeons.See Article page 77. The addition of cannulas …

Platelet Quiescence in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Bypass Graft Surgery Open

Kiran Sarathy, George A. Wells, Kuljit Singh, Étienne Couture, Aun‐Yeong Chong , et al. · 2021

Background The optimal antiplatelet strategy for patients with acute coronary syndromes who require coronary artery bypass surgery remains unclear. While a more potent antiplatelet regimen will predispose to perioperative bleeding, it is h…

Commentary: The Goldilocks annuloplasty: Not too big, not too small Open

Kenza Rahmouni, Fraser D. Rubens · 2021

Derivation of Patient-Defined Adverse Cardiovascular and Noncardiovascular Events Through a Modified Delphi Process Open

Louise Y. Sun, Jillian Rodger, Lisa Duffett, Heather Tulloch, Andrew M. Crean , et al. · 2021

This study defined PACE as a versatile, patient-centered outcome through a consensus process with input from patients, caregivers, and clinicians. Given the paucity of patient-centered outcomes in cardiovascular research, PACE may be consi…

Commentary: Expertise in fitting square pegs in round holes Open

Fraser D. Rubens · 2020

Central MessageSuccessful innovation exemplifies an understanding of 3D anatomy. This application is a novel means to implant larger valves, but it comes with a concern of coronary movement that must be recognized.See Article page 13. Succ…

Commentary: Lung recruitment: Why is this not on my radar? Open

Fraser D. Rubens · 2020

Commentary: What lessons can a surgeon learn from something rare? Open

Kenza Rahmouni, Fraser D. Rubens · 2020

Commentary: All we like iSheep: Reflections of an early adopter Open

Fraser D. Rubens · 2020

Diagnosing acute aortic syndrome: a Canadian clinical practice guideline Open

Robert Ohle, Justin Yan, Krishan Yadav, Alexis Cournoyer, David W. Savage , et al. · 2020

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It is a clinical spectrum of diagnoses including aortic dissection, …

Cardiothoracic Surgical Residency Programs: A Pandemic Playbook Open

Bobby Yanagawa, Erin Mills Iannacone, Tsuyoshi Kaneko, Fraser D. Rubens, David T. Cooke · 2020

Commentary: Missing the mark but we must keep trying Open

Thin Xuan Vo, Fraser D. Rubens · 2020

Central MessageThe rate of revascularization after aortic valve intervention is unclear. Further insight will assist with heart team planning, especially in the era of emerging transcatheter therapies.See Article page 91. The rate of revas…

Commentary: Enough is enough, but when is enough enough? Open

Janet M.C. Ngu, Fraser D. Rubens · 2020

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