Douglas J. Taatjes
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View article: Optimizing Research Visibility: The Role of Investigators and Shared (Core) Research Resources in Publications Using RRIDs
Optimizing Research Visibility: The Role of Investigators and Shared (Core) Research Resources in Publications Using RRIDs Open
View article: August in focus in HCB
August in focus in HCB Open
View article: July in focus in HCB
July in focus in HCB Open
View article: Outer Membrane Vesicles Secreted by <i>Bacteroides fragilis</i> Inhibit CFTR Chloride Secretion by Human Colon Organoids
Outer Membrane Vesicles Secreted by <i>Bacteroides fragilis</i> Inhibit CFTR Chloride Secretion by Human Colon Organoids Open
The goals of this study were to develop a model to study host pathogen interactions in primary human colon cells and to test the hypothesis that Bacteroides fragilis toxin (BFT) secreted in outer membrane vesicles (OMVs) modulates mucosal …
View article: June in focus in HCB
June in focus in HCB Open
View article: May In focus in HCB
May In focus in HCB Open
View article: April In focus in HCB
April In focus in HCB Open
View article: March in focus in HCB
March in focus in HCB Open
View article: Extracellular Particles Derived from Mesenchymal Stromal Cells Reduce <i>Pseudomonas aeruginosa</i> Lung Infection and Inflammation in Mice
Extracellular Particles Derived from Mesenchymal Stromal Cells Reduce <i>Pseudomonas aeruginosa</i> Lung Infection and Inflammation in Mice Open
The World Health Organization and the U.S. Centers for Disease Control and Prevention have reported that antibiotic resistant infections with Pseudomonas aeruginosa present a significant health risk world-wide. In the genetic disease Cysti…
View article: February In focus in HCB
February In focus in HCB Open
View article: January In focus in HCB
January In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: <i>P. aeruginosa</i> tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in cystic fibrosis
<i>P. aeruginosa</i> tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in cystic fibrosis Open
The experiments in this report identify a novel mechanism, whereby tobramycin reduces inflammation in two models of CF. Tobramycin increased the secretion of tRNA-fMet halves in OMVs secreted by P. aeruginosa, which reduced the OMV-LPS-ind…
View article: In focus in HCB
In focus in HCB Open
View article: <i>P. aeruginosa</i>tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis
<i>P. aeruginosa</i>tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis Open
Although tobramycin increases lung function in people with cystic fibrosis (pwCF), the density of Pseudomonas aeruginosa (P. aeruginosa) in the lungs is only modestly reduced by tobramycin; hence, the mechanism whereby tobramycin improves …
View article: In focus in HCB
In focus in HCB Open
View article: Illumination Power, Stability, and Linearity Measurements for Confocal, Widefield and Multiphoton Microscopes v1
Illumination Power, Stability, and Linearity Measurements for Confocal, Widefield and Multiphoton Microscopes v1 Open
To obtain accurate, reproducible, and interpretable data when conducting imaging experiments, it is critical to consider external factors affecting data acquisition at various steps of the experimental workflow. Illumination power and stab…
View article: In focus in HCB
In focus in HCB Open
View article: Extracellular vesicles secreted by primary human bronchial epithelial cells reduce <i>Pseudomonas aeruginosa</i> burden and inflammation in cystic fibrosis mouse lung
Extracellular vesicles secreted by primary human bronchial epithelial cells reduce <i>Pseudomonas aeruginosa</i> burden and inflammation in cystic fibrosis mouse lung Open
Our findings show that extracellular vesicles secreted by primary human bronchial epithelial cells significantly reduce Pseudomonas aeruginosa burden, inflammation, and weight loss in a cystic fibrosis mouse model of infection.
View article: In focus in HCB
In focus in HCB Open
View article: In focus in HCB
In focus in HCB Open
View article: Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis Open
View article: 17 Let-7b-5p loaded mesenchymal stromal cell extracellular vesicles reduce Pseudomonas aeruginosa burden in cystic fibrosis mice
17 Let-7b-5p loaded mesenchymal stromal cell extracellular vesicles reduce Pseudomonas aeruginosa burden in cystic fibrosis mice Open
View article: Community-developed checklists for publishing images and image analyses
Community-developed checklists for publishing images and image analyses Open