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View article: Incubator-Free Organoid Culture in a Sealed Recirculatory System
Incubator-Free Organoid Culture in a Sealed Recirculatory System Open
Organoids are powerful tools for studying development and disease, offering realistic organ-like human and animal tissues and facilitating experimental observation compared to live animal models. However, traditional organoid culture metho…
View article: Microscope Upcycling: Transforming legacy microscopes into automated cloud-integrated imaging systems
Microscope Upcycling: Transforming legacy microscopes into automated cloud-integrated imaging systems Open
Computerized microscopes improve repeatability, throughput, antisepsis, data analysis and data sharing in the biological laboratory, but these machines are cost-prohibitive in most academic environments. This is a barrier into collecting t…
View article: A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring
A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring Open
The analysis of tissue cultures, particularly brain organoids, requires a sophisticated integration and coordination of multiple technologies for monitoring and measuring. We have developed an automated research platform enabling independe…
View article: Internet-Connected Cortical Organoids for Project-Based Stem Cell and Neuroscience Education
Internet-Connected Cortical Organoids for Project-Based Stem Cell and Neuroscience Education Open
The introduction of Internet-connected technologies to the classroom has the potential to revolutionize STEM education by allowing students to perform experiments in complex models that are unattainable in traditional teaching laboratories…
View article: PolyPhy: Open Source Generator for 3D Printed Bio-inspired Objects
PolyPhy: Open Source Generator for 3D Printed Bio-inspired Objects Open
In this demo, we present an open source methodology for turning triangle meshes into biologically inspired 3D printable objects using an algorithm based on the behavior of the Physarum polycephalum slime mold. Users can import watertight 3…
View article: Internet-connected cortical organoids for project-based stem cell and neuroscience education
Internet-connected cortical organoids for project-based stem cell and neuroscience education Open
SUMMARY The introduction of internet-connected technologies to the classroom has the potential to revolutionize STEM education by allowing students to perform experiments in complex models that are unattainable in traditional teaching labo…
View article: Scaffolding Generation using a 3D Physarum Polycephalum Simulation
Scaffolding Generation using a 3D Physarum Polycephalum Simulation Open
In this demo, we present a novel technique for approximating topologically\noptimal scaffoldings for 3D printed objects using a Monte Carlo algorithm based\non the foraging behavior of the Physarum polycephalum slime mold. As a case\nstudy…
View article: Cloud-controlled microscopy enables remote project-based biology education in Latinx communities in the United States and Latin America
Cloud-controlled microscopy enables remote project-based biology education in Latinx communities in the United States and Latin America Open
Project-based learning (PBL) has long been recognized as an effective way to teach complex biology concepts. However, not all institutions have the resources to facilitate effective project-based coursework for students. We have developed …