Drissa Coulibaly
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View article: High Antibiotic Resistance in Pediatric Urinary Tract Infection in Bamako, Mali – The First Study in a Pediatric Population.
High Antibiotic Resistance in Pediatric Urinary Tract Infection in Bamako, Mali – The First Study in a Pediatric Population. Open
Background: Urinary tract infection in children may cause long-term complications. Therefore, it should be recognized early and treated appropriately. Objective: This study investigates the prevalence of antibiotic resistance in pediatric …
View article: The Key to Combating Sickle Cell Disease in High-Prevalence Regions Like Mali: Hemoglobin Electrophoresis for All, From Birth to Marriage
The Key to Combating Sickle Cell Disease in High-Prevalence Regions Like Mali: Hemoglobin Electrophoresis for All, From Birth to Marriage Open
Background: Sickle cell disease (SCD) is a significant public health concern, particularly in Africa, where approximately 200,000 newborns are affected annually. West African countries show carrier rates between 5% and 20%, with Mali avera…
View article: A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses
A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses Open
View article: Gut microbiota influences Plasmodium falciparum malaria susceptibility
Gut microbiota influences Plasmodium falciparum malaria susceptibility Open
Further studies are needed to confirm these findings, which point the way to strategies aimed at reducing the risk of malaria by modulating gut microbiota components in at-risk populations.
View article: Evaluation of Surgical Treatment of Recent Traumatic Achilles Tendon Ruptures Using the Bosworth Technique: A Report of 12 Cases
Evaluation of Surgical Treatment of Recent Traumatic Achilles Tendon Ruptures Using the Bosworth Technique: A Report of 12 Cases Open
View article: Etude de la composition phytochimique et activités antioxydante des feuilles du <i>Moringa oleifera</i>. Lam (Moringaceae) dans les régions de Kita (Mali) et de Thiès (Sénégal)
Etude de la composition phytochimique et activités antioxydante des feuilles du <i>Moringa oleifera</i>. Lam (Moringaceae) dans les régions de Kita (Mali) et de Thiès (Sénégal) Open
Le règne végétal contient une très grande variété de molécules bioactives telles que des composés phénoliques, des terpènes et des alcaloïdes qui peuvent présenter des propriétés antioxydantes. L’objectif de la présente étude était de déte…
View article: Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens
Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens Open
Children with hemoglobin AC or AS have decreased susceptibility to clinical malaria. Parasite variant surface antigen (VSA) presentation on the surface of infected erythrocytes is altered in erythrocytes with hemoglobin C (Hb AC) or sickle…
View article: Immune gene expression changes more during a malaria transmission season than between consecutive seasons
Immune gene expression changes more during a malaria transmission season than between consecutive seasons Open
Plasmodium parasites, the causative organism of malaria, caused over 600,000 deaths in 2022. In Mali, Plasmodium falciparum causes the majority of malaria cases and deaths and is transmitted seasonally. Anti-malarial immunity develops slow…
View article: Immune gene expression changes more during a malaria transmission season than between consecutive seasons.
Immune gene expression changes more during a malaria transmission season than between consecutive seasons. Open
Plasmodium parasites caused over 600,000 deaths in 2022. In Mali, P. falciparum is responsible for the majority of malaria cases and deaths and is transmitted seasonally. Anti-malarial immunity develops slowly over repeated exposures to P.…
View article: Gene expression analyses reveal differences in children’s response to malaria according to their age
Gene expression analyses reveal differences in children’s response to malaria according to their age Open
View article: Disjunction of the Pubic Symphysis in the Chu Gabriel Toure: Therapeutic Aspects
Disjunction of the Pubic Symphysis in the Chu Gabriel Toure: Therapeutic Aspects Open
View article: OA-183 Dynamic of molecular and resistance markers prevalence of Plasmodium falciparum during the seasonal malaria chemoprevention campaign in school aged children in Bandiagara, Mali
OA-183 Dynamic of molecular and resistance markers prevalence of Plasmodium falciparum during the seasonal malaria chemoprevention campaign in school aged children in Bandiagara, Mali Open
Background Recently, the World Health Organization (WHO) has recommended to extend the seasonal malaria chemoprevention (SMC) with Sulfadoxine-pyrimethamine plus amodiaquine (SP-AQ) strategy to school aged children and to use alternative a…
View article: Gene expression analyses reveal differences in children’s response to malaria according to their age
Gene expression analyses reveal differences in children’s response to malaria according to their age Open
In Bandiagara, Mali, children experience on average two clinical malaria episodes per season. However, even in the same transmission area, the number of uncomplicated symptomatic infections, and their parasitemia, vary dramatically among c…
View article: Gene expression analyses reveal differences in children’s response to malaria according to their age
Gene expression analyses reveal differences in children’s response to malaria according to their age Open
In Bandiagara, Mali, children experience on average two clinical malaria episodes per season. However, even in the same transmission area, the number of uncomplicated symptomatic infections, and their parasitemia, vary dramatically among c…
View article: Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s
Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s Open
Antibody responses to variant surface antigens (VSAs) produced by the malaria parasite Plasmodium falciparum may contribute to age-related natural immunity to severe malaria. One VSA family, P. falciparum erythrocyte membrane protein-1 (Pf…
View article: Randomized Field Trial to Assess the Safety and Efficacy of Dihydroartemisinin-Piperaquine for Seasonal Malaria Chemoprevention in School-Aged Children in Bandiagara, Mali
Randomized Field Trial to Assess the Safety and Efficacy of Dihydroartemisinin-Piperaquine for Seasonal Malaria Chemoprevention in School-Aged Children in Bandiagara, Mali Open
Background Owing to the increased cases of malaria in older children, the World Health Organization has recently recommended extending seasonal malaria chemoprevention (SMC) to children >5 years of age and using other effective drugs fo…
View article: Immunogenomic profile at baseline predicts host susceptibility to clinical malaria
Immunogenomic profile at baseline predicts host susceptibility to clinical malaria Open
Introduction Host gene and protein expression impact susceptibility to clinical malaria, but the balance of immune cell populations, cytokines and genes that contributes to protection, remains incompletely understood. Little is known about…
View article: 272 Differential expression of two Plasmodium falciparum variant surface antigen families in Malian children with cerebral malaria compared to mild malaria
272 Differential expression of two Plasmodium falciparum variant surface antigen families in Malian children with cerebral malaria compared to mild malaria Open
OBJECTIVES/GOALS: Recent in vitro evidence suggests that diverse parasite protein families called RIFINs and STEVORs are displayed on the surface of infected red blood cells and may have a role in severe malaria, but they remain sparsely s…
View article: IFNγ, TNFα polymorphisms and IFNγ serum levels are associated with the clearance of drug-resistant P. falciparum in Malian children
IFNγ, TNFα polymorphisms and IFNγ serum levels are associated with the clearance of drug-resistant P. falciparum in Malian children Open
Host immunity has been suggested to clear drug-resistant parasites in malaria-endemic settings. However, the immunogenetic mechanisms involved in parasite clearance are poorly understood. Characterizing the host's immunity and genes involv…
View article: Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles
Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles Open
Plasmodium parasites caused 241 million cases of malaria and over 600,000 deaths in 2020. Both P . falciparum and P . ovale are endemic to Mali and cause clinical malaria, with P . falciparum infections typically being more severe. Here, w…
View article: Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali Open
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria ch…
View article: Malian children infected with <i>Plasmodium ovale</i> and <i>Plasmodium falciparum</i> display very similar gene expression profiles
Malian children infected with <i>Plasmodium ovale</i> and <i>Plasmodium falciparum</i> display very similar gene expression profiles Open
Plasmodium parasites caused 241 million cases of malaria and over 600,000 deaths in 2020. Both P. falciparum and P. ovale are endemic to Mali and cause malaria illness, with P. falciparum infections typically being more severe. Here, we se…
View article: PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial
PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial Open
View article: Serologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria
Serologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria Open
We used a protein microarray featuring Plasmodium falciparum field variants of a merozoite surface antigen to examine malaria exposure in Malian children with different severe malaria syndromes. Unlike children with cerebral malaria alone …
View article: Fracture of the Penis: About a Case of Delay in Management at the Nianankoro Fomba Hospital in Segou-Mali
Fracture of the Penis: About a Case of Delay in Management at the Nianankoro Fomba Hospital in Segou-Mali Open
Introduction: Fracture of the penis is a rare uro-andrological emergency defined as the rupture of the tunica albuginea of the erect penis most often during sexual intercourse. Surgical exploration and repair of the albuginea breach as soo…
View article: Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome
Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome Open
View article: Effect Of Trabeculectomy On Ocular Biometry And Refractive Errors In Pediatric Glaucoma
Effect Of Trabeculectomy On Ocular Biometry And Refractive Errors In Pediatric Glaucoma Open
Background: Pediatric glaucoma triggers refractive errors by modifying the biometry of the eye. This study was conducted with the objective of estimating the short-term biometric and refractive changes prior to and post trabeculectomy in p…
View article: Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes
Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes Open
View article: Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation
Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation Open
View article: High-throughput detection of eukaryotic parasites and arboviruses in mosquitoes
High-throughput detection of eukaryotic parasites and arboviruses in mosquitoes Open
Vector-borne pathogens cause many human infectious diseases and are responsible for high mortality and morbidity throughout the world. They can also cause livestock epidemics with dramatic social and economic consequences. Due to its high …