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View article: Accurate profiling of full-length Fv in highly homologous antibody libraries using UMI tagged short reads
Accurate profiling of full-length Fv in highly homologous antibody libraries using UMI tagged short reads Open
Deep parallel sequencing (NGS) is a viable tool for monitoring scFv and Fab library dynamics in many antibody engineering high-throughput screening efforts. Although very useful, the commonly used Illumina NGS platform cannot handle the en…
View article: Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads
Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads Open
Data consists of raw Illumina MiSeq 2x250bp reads from the Fab mini library mix as described in the journal publication "Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads".
View article: Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads
Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads Open
Data consists of raw Illumina MiSeq 2x250bp reads from the Fab mini library mix as described in the journal publication "Accurate profiling of full length Fv in highly homologous antibody libraries using UMI tagged short reads".
View article: Principles for computational design of binding antibodies
Principles for computational design of binding antibodies Open
Significance Antibodies are the most versatile class of binding molecule known, and have numerous applications in biomedicine. Computational design of antibodies, however, poses unusual difficulties relative to previously designed proteins…