Dror Mandel
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View article: Effects of Donor Human Milk and Formula Supplementation on Bone Metabolism and Clinical Outcomes in Preterm Infants Receiving Mother’s Own Milk
Effects of Donor Human Milk and Formula Supplementation on Bone Metabolism and Clinical Outcomes in Preterm Infants Receiving Mother’s Own Milk Open
Background: Human milk (HM) is the optimal nutrition for preterm infants, but supplementation is often required to meet their unique nutritional needs. Donor human milk (DHM) and preterm formula are commonly used alternatives, yet their im…
View article: Associations Between Prolonged Breast-Feeding, Formula Supplementation, and Weight-for-Age Trajectories Through Five Years
Associations Between Prolonged Breast-Feeding, Formula Supplementation, and Weight-for-Age Trajectories Through Five Years Open
Purpose The associations of prolonged breastfeeding beyond one year on infant growth rates remain inconclusive as are those of supplemental formula use. This study aimed to monitor and describe the growth patterns of infants breastfed for …
View article: The Clinical Value of Capillary Blood Cartridge-Based Testing in Neonatal Jitteriness: A Re-Evaluation of the Diagnostic Approach
The Clinical Value of Capillary Blood Cartridge-Based Testing in Neonatal Jitteriness: A Re-Evaluation of the Diagnostic Approach Open
Objective: This study assessed the utility of capillary blood cartridge-based analysis in evaluating neonatal jitteriness (NJ). Methods: In this retrospective study, we compared outcomes between neonates (37–41 weeks of gestation) diagnose…
View article: Hemolytic disease of fetus and newborn course, management and outcomes - an analysis based on the Israeli Maccabi database
Hemolytic disease of fetus and newborn course, management and outcomes - an analysis based on the Israeli Maccabi database Open
Objective: Hemolytic disease of the fetus and newborn (HDFN) can cause severe prenatal and postnatal outcomes. The main objective of this study is to understand the clinical impact of HDFN on pregnant women and newborns. Study Design: A re…
View article: Time of Birth and the Risk of Adverse Maternal and Neonatal Outcomes—A Retrospective Cohort Study
Time of Birth and the Risk of Adverse Maternal and Neonatal Outcomes—A Retrospective Cohort Study Open
Objectives: To determine whether in a labor floor housed continuously by senior physicians the risk of adverse maternal and neonatal outcome is affected by time of delivery. Methods: This retrospective cohort study, conducted at a tertiary…
View article: National Rapid Genome Sequencing in Neonatal Intensive Care
National Rapid Genome Sequencing in Neonatal Intensive Care Open
Importance National implementation of rapid trio genome sequencing (rtGS) in a clinical acute setting is essential to ensure advanced and equitable care for ill neonates. Objective To evaluate the feasibility, diagnostic efficacy, and clin…
View article: Blood Glucose, Lactate and Platelet Count in Infants with Spontaneous Intestinal Perforation versus Necrotizing Enterocolitis—A Pilot Study
Blood Glucose, Lactate and Platelet Count in Infants with Spontaneous Intestinal Perforation versus Necrotizing Enterocolitis—A Pilot Study Open
The incidence of spontaneous intestinal perforation (SIP) increases up to 10% with decreasing gestational age (GA). We aimed to explore early biomarkers for predicting SIP in preterm infants. In this case–control study, neonates born at ≤3…
View article: Upper gastrointestinal series in healthy neonates with bilious vomiting—is it still obvious? A retrospective observational study
Upper gastrointestinal series in healthy neonates with bilious vomiting—is it still obvious? A retrospective observational study Open
Aim Demand for upper gastrointestinal contrast series (UGI) to investigate bilious vomiting (BV) has increased in recent years, mostly due to greater awareness of the need to rule out malrotation and midgut volvulus (MGV). We aimed to exam…
View article: Human Milk Oligosaccharide Profile across Lactation Stages in Israeli Women—A Prospective Observational Study
Human Milk Oligosaccharide Profile across Lactation Stages in Israeli Women—A Prospective Observational Study Open
Human milk oligosaccharides (HMOs) stimulate the growth of gut commensals, prevent the adhesion of enteropathogens and modulate host immunity. The major factors influencing variations in the HMO profile are polymorphisms in the secretor (S…
View article: Maternal Exposure to Polychlorinated Biphenyls and Asthma, Allergic Rhinitis and Atopic Dermatitis in the Offspring: The Environmental Health Fund Birth Cohort
Maternal Exposure to Polychlorinated Biphenyls and Asthma, Allergic Rhinitis and Atopic Dermatitis in the Offspring: The Environmental Health Fund Birth Cohort Open
Background: Polychlorinated biphenyls (PCBs) are persistent organic pollutants banned for use worldwide. Due to their biodegradation resistance, they accumulate along the food chain and in the environment. Maternal exposure to PCBs may aff…
View article: The Glycemic Response to Infant Formulas: A Randomized Clinical Trial
The Glycemic Response to Infant Formulas: A Randomized Clinical Trial Open
Background: Commercial infant formulas attempt to imitate human milk’s unique composition. However, lactose-free and milk protein-free formulas are often chosen due to medical reasons or personal preferences. The aim of this study was to d…
View article: Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants
Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants Open
ClinicalTrials.gov Identifier: NCT02510560.
View article: Carriage of vancomycin-resistant <i>Enterococcus faecium</i> in infants following an outbreak in the neonatal intensive care unit: time to clearance of carriage and use of molecular methods to detect colonization
Carriage of vancomycin-resistant <i>Enterococcus faecium</i> in infants following an outbreak in the neonatal intensive care unit: time to clearance of carriage and use of molecular methods to detect colonization Open
Among 46 infants colonized with vancomycin-resistant Enterococcus faecium during an outbreak in a neonatal intensive care unit, the estimated time until half had achieved clearance was 217 days. All 40 infants who completed follow-up clear…
View article: Carbohydrate content of human milk is affected by seasonal variations: a retrospective observational study
Carbohydrate content of human milk is affected by seasonal variations: a retrospective observational study Open
Background Previous studies have suggested seasonal variation in macronutrient content of milk produced from animals. The influence of seasonal variation upon human milk macronutrient content has not been elucidated. This study aimed to co…
View article: Maternal and Newborn Thyroid Hormone, and the Association With Polychlorinated Biphenyls (PCBs) Burden: The EHF (Environmental Health Fund) Birth Cohort
Maternal and Newborn Thyroid Hormone, and the Association With Polychlorinated Biphenyls (PCBs) Burden: The EHF (Environmental Health Fund) Birth Cohort Open
Background: Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants found in human tissues. PCBs can be transferred through the placenta and may disrupt the maternal thyroid homeostasis, and affect fetal thyroid hormone …
View article: The Glycemic Response to Infant Formulas: a Randomized Clinical Trial
The Glycemic Response to Infant Formulas: a Randomized Clinical Trial Open
Objectives: Commercial infant formulas attempt to imitate the unique composition of human milk, which contributes to its distinctive influence on glycemic and insulinemic responses. However, lactose-free and milk protein-free formulas are …
View article: Significant Loss of Macronutrients During Passage Through Feeding Tube
Significant Loss of Macronutrients During Passage Through Feeding Tube Open
Objective: Feeding infants born before week 34 of gestation is based mainly on providing nutrition directly to the gastrointestinal tract through a nasogastric tube. Little is known about the impact of formulas passage through nasogastric …
View article: P53 Exposure of infants to brominated flame retardants through breast-milk
P53 Exposure of infants to brominated flame retardants through breast-milk Open
Introduction Polybrominated Diphenyl Ethers (PBDEs) are non-biodegradable flame retardants, accumulated in biological systems and acting as endocrine disruptors. Breast feeding is a major route of exposure in infancy. Taken together with t…
View article: Nutrition and the Use of Supplements in Women During Pregnancy: A Cross-Sectional Survey
Nutrition and the Use of Supplements in Women During Pregnancy: A Cross-Sectional Survey Open
Objective: A healthy diet during pregnancy is essential to ensure optimal fetal growth and development. Women’s awareness of dietary guidelines may assist them in following a healthy diet for themselves and their unborn babies. The Institu…
View article: SAT-271 Higher C-Peptide Levels and Glucose Requirements May Identify Neonates with Transient Hyperinsulinism Hypoglycemia Who Will Benefit from Diazoxide Treatment
SAT-271 Higher C-Peptide Levels and Glucose Requirements May Identify Neonates with Transient Hyperinsulinism Hypoglycemia Who Will Benefit from Diazoxide Treatment Open
Background: Hyperinsulinism hypoglycemia in infants is characterized by inappropriate insulin secretion from pancreatic beta-cells. Prompt recognition and treatment are essential to decrease the risk of neurologic sequelae. Neonates with t…