Duncan Macrae
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View article: Ventilator Settings in Critically Ill Pediatric Patients (VESPer)—insights from a European Registry
Ventilator Settings in Critically Ill Pediatric Patients (VESPer)—insights from a European Registry Open
Aim To explore ventilator settings, ventilation variables and parameters in critically ill pediatric patients across European Centers. Methods International, multicenter, prospective observational study, collecting ventilation data for 7 d…
View article: A standard lexicon of terms for area‐based conservation version 1.0
A standard lexicon of terms for area‐based conservation version 1.0 Open
Target 3 in the Kunming–Montreal Global Biodiversity Framework (GBF) calls for protecting at least 30% of the world's lands and waters in area‐based conservation approaches by 2030. This ambitious 30×30 target has spurred great interest am…
View article: Outcomes of pediatric ventricular assist device in the United States: an analysis of the national inpatient sample database
Outcomes of pediatric ventricular assist device in the United States: an analysis of the national inpatient sample database Open
Background Infants and children with advanced heart failure, refractory to medications, are frequently supported with ventricular assist devices (VAD). Purpose To describe the patient characteristics of those who were supported with VADs a…
View article: Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2)
Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) Open
OBJECTIVES: We sought to update our 2015 work in the Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS), considering new e…
View article: Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT
Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT Open
BACKGROUND: Daily assessment of patient readiness for liberation from invasive mechanical ventilation can reduce the duration of ventilation. However, there is uncertainty about the effectiveness of this in a paediatric population.
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View article: Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units
Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units Open
isrctn.org Identifier: ISRCTN16998143.
View article: Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs
Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs Open
Sepsis is a major worldwide healthcare issue with unmet clinical need. Despite extensive animal research in this area, successful clinical translation has been largely unsuccessful. We propose one reason for this is that, sometimes, the ex…
View article: In-hospital interstage improves interstage survival after the Norwood stage 1 operation
In-hospital interstage improves interstage survival after the Norwood stage 1 operation Open
OBJECTIVES The interstage mortality rate after a Norwood stage 1 operation remains 12–20% in current series. In-hospital interstage facilitates escalation of care, possibly improving outcome. METHODS A retrospective study was designed for …
View article: Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial
Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial Open
Introduction Weaning from ventilation is a complex process involving several stages that include recognition of patient readiness to begin the weaning process, steps to reduce ventilation while optimising sedation in order not to induce di…
View article: Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative
Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative Open
Objectives: To date, there are no published guidelines to direct RBC transfusion decision-making specifically for critically ill children. We present the recommendations from the Pediatric Critical Care Transfusion and Anemia Expertise Ini…
View article: Recommendations on RBC Transfusions for Critically Ill Children With Nonhemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative
Recommendations on RBC Transfusions for Critically Ill Children With Nonhemorrhagic Shock From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative Open
Objectives: To present the recommendations and supporting literature for RBC transfusions in critically ill children with nonhemorrhagic shock developed by the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. Design: Co…
View article: Mitigating Latent Threats Identified through an Embedded In Situ Simulation Program and Their Comparison to Patient Safety Incidents: A Retrospective Review
Mitigating Latent Threats Identified through an Embedded In Situ Simulation Program and Their Comparison to Patient Safety Incidents: A Retrospective Review Open
An in situ simulation program can identify important LTs which traditional reporting systems miss. Subsequent improvements in workplace systems and resources can improve efficiency and remove error traps.
View article: Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC)
Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC) Open
These recommendations should help to harmonise the approach to paediatric mechanical ventilation and can be proposed as a standard-of-care applicable in daily clinical practice and clinical research.
View article: Nursing & parental perceptions of neonatal care in Central Vietnam: a longitudinal qualitative study
Nursing & parental perceptions of neonatal care in Central Vietnam: a longitudinal qualitative study Open
Qualitative interviews highlighted the short term effect that the introduction of an educational intervention can have on both nursing attitudes towards and parental experience of care in one neonatal unit in central Vietnam. Nurses shared…
View article: Endocrinologic Diseases in Pediatric Cardiac Intensive Care
Endocrinologic Diseases in Pediatric Cardiac Intensive Care Open
Objectives: The objectives of this review are to discuss the pathophysiology, clinical impact and treatment of hyperglycemia, and disturbances in thyroid and adrenal function prior to and following cardiac surgery in children. Data Source:…