Duneia McManus
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View article: Investigating donor CD8+ T cell differentiation post-experimental aHSCT in GVHD target tissues 3639
Investigating donor CD8+ T cell differentiation post-experimental aHSCT in GVHD target tissues 3639 Open
Description The onset of graft-vs-host-disease (GVHD) remains a major complication limiting the application of allogeneic hematopoietic stem cell transplantation (aHSCT) as a form of treatment for hematological malignancies. GVHD affects 3…
View article: Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT
Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT Open
The current approach to minimize transplant-associated complications, including graft-versus-host disease (GVHD) includes long-term pharmacological immune suppression frequently accompanied by unwanted side effects. Advances in targeted im…
View article: Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E Open
The intestine is the home to the largest number of immune cells in the body. The small and large intestinal immune systems police exposure to exogenous antigens and modulate responses to potent microbially derived immune stimuli. For this …
View article: TB or not TB: Type 3 ILCs may decide
TB or not TB: Type 3 ILCs may decide Open
Mouse models are used to show that type 3 innate lymphoid cells provide early protection against Mtb infection.