Dushyant Singh Dahiya
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View article: Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology
Genetic predeterminants and recent advancements in steatotic liver disease: A roadmap toward precision hepatology Open
Steatotic liver disease (SLD) encompasses a group of disorders characterized by the excessive accumulation of fat in the liver. It is classified into four categories based on clinical manifestations: Metabolic dysfunction-associated SLD (M…
View article: Effectiveness of endoscopy in patients with concomitant gastrointestinal bleeding and acute coronary syndrome: A systematic review
Effectiveness of endoscopy in patients with concomitant gastrointestinal bleeding and acute coronary syndrome: A systematic review Open
BACKGROUND Gastrointestinal bleeding (GIB) is a critical complication often seen in patients with acute coronary syndrome (ACS), especially those undergoing dual antiplatelet therapy. GIB is associated with increased mortality and prolonge…
View article: <scp>GastroGPT</scp> Pioneering Specialized <scp>AI</scp> in Gastroenterology: Strengths, Pitfalls, and the Road to Clinical Integration
<span>GastroGPT</span> Pioneering Specialized <span>AI</span> in Gastroenterology: Strengths, Pitfalls, and the Road to Clinical Integration Open
GastroGPT, a transformer‐based large language model, has been developed specifically for gastroenterology. It exhibited improved ability in clinical tasks compared to a general‐purpose model such as GPT‐4, Bard and Claude. GastroGPT was de…
View article: Unexpected Hepatotoxicity in Psoriasis: Deranged Liver Enzymes and Steatosis Secondary to Secukinumab Treatment
Unexpected Hepatotoxicity in Psoriasis: Deranged Liver Enzymes and Steatosis Secondary to Secukinumab Treatment Open
Psoriasis is a chronic inflammatory disease characterized by scaly, erythematous plaques on any part of the body, especially the extensor surfaces. Secukinumab, an IL-17A inhibitor, is widely used clinically for conditions such as psoriasi…
View article: Gastric Motility Disorders Post Organ Transplantation—A Comprehensive Review
Gastric Motility Disorders Post Organ Transplantation—A Comprehensive Review Open
Motility disorders, particularly gastroparesis, are prevalent complications following solid organ transplantation, significantly impacting quality of life, nutritional status, graft survival, and mortality. This comprehensive review synthe…
View article: Artificial Intelligence in Population-Level Gastroenterology and Hepatology: A Comprehensive Review of Public Health Applications and Quantitative Impact
Artificial Intelligence in Population-Level Gastroenterology and Hepatology: A Comprehensive Review of Public Health Applications and Quantitative Impact Open
Background Artificial intelligence (AI), which includes machine learning and deep learning, is fundamentally changing public health in gastroenterology and hepatology—fields grappling with a significant global disease burden. Objective Thi…
View article: Diagnostic Performance of Metagenomic Next-Generation Sequencing (mNGS) and Culture in Infected Pancreatic Necrosis: A Systematic Review and Meta-Analysis
Diagnostic Performance of Metagenomic Next-Generation Sequencing (mNGS) and Culture in Infected Pancreatic Necrosis: A Systematic Review and Meta-Analysis Open
Background Infected pancreatic necrosis (IPN) is a severe complication of acute pancreatitis, requiring prompt diagnosis. Conventional microbial culture, the current gold standard, has limitations in sensitivity and turnaround time. Metage…
View article: Postgraduate gastroenterology training and continuing medical education in Africa: challenges, opportunities, and future directions
Postgraduate gastroenterology training and continuing medical education in Africa: challenges, opportunities, and future directions Open
Africa faces a critical shortage of gastroenterologists amidst a growing burden of digestive diseases. Despite an alarming rise in gastrointestinal (GI) conditions – including peptic ulcers, GI cancers, and infectious colitis – postgraduat…
View article: Primary precut techniques for biliary cannulation: a systematic review and meta-analysis
Primary precut techniques for biliary cannulation: a systematic review and meta-analysis Open
Primary precut sphincterotomy appears to be an effective and safe technique for biliary cannulation in ERCP. These findings support its consideration as a viable first-line approach in appropriate clinical settings.
View article: Real-Time Artificial Intelligence Versus Standard Colonoscopy in the Early Detection of Colorectal Cancer: A Systematic Review and Meta-Analysis
Real-Time Artificial Intelligence Versus Standard Colonoscopy in the Early Detection of Colorectal Cancer: A Systematic Review and Meta-Analysis Open
Background: Colonoscopy remains the gold standard for colorectal cancer screening. Deep learning systems with real-time computer-aided polyp detection (CADe) demonstrate high accuracy in controlled research settings and preliminary randomi…
View article: The Evolution of Value-Based Care: Why Cost-Effectiveness Matters in Gastroenterology
The Evolution of Value-Based Care: Why Cost-Effectiveness Matters in Gastroenterology Open
View article: Efficacy and Safety of a Novel Technique Utilizing Endoscopic Ultrasound Guided Fine Needle Injection of Botulinum Toxin and Balloon Dilatation in Achalasia.
Efficacy and Safety of a Novel Technique Utilizing Endoscopic Ultrasound Guided Fine Needle Injection of Botulinum Toxin and Balloon Dilatation in Achalasia. Open
View article: The Current Landscape of Pancreatic Cancer Management in Sub‐Saharan Africa – A Perspective Review
The Current Landscape of Pancreatic Cancer Management in Sub‐Saharan Africa – A Perspective Review Open
Background and Aims Pancreatic cancer remains a significant public health challenge in Sub‐Saharan Africa (SSA), with a high mortality‐to‐incidence ratio driven by late‐stage diagnoses, limited therapeutic access, and systemic healthcare d…
View article: Sex, racial, and ethnic disparities in United States liver transplantation clinical trials
Sex, racial, and ethnic disparities in United States liver transplantation clinical trials Open
BACKGROUND Regulatory agencies are increasingly recognizing that minority trial representation is inadequate, contributing to healthcare disparities. The scope of minority population disparities in clinical trial participation remains uncl…
View article: Management Strategies for Zenker’s Diverticulum: A Comprehensive Review
Management Strategies for Zenker’s Diverticulum: A Comprehensive Review Open
Zenker’s diverticulum (ZD) is an esophageal condition that results in an outpouching of the mucosal layer through a weakened area in the hypopharyngeal wall. This condition can cause symptoms like dysphagia, regurgitation, and aspiration, …
View article: Does First‐Time Colon Cancer Screening Beyond Age 75 Reduce Cancer Risk Without Significant Complications? Insights From a Large <scp>US</scp> Retrospective Study
Does First‐Time Colon Cancer Screening Beyond Age 75 Reduce Cancer Risk Without Significant Complications? Insights From a Large <span>US</span> Retrospective Study Open
Introduction Colorectal cancer (CRC) is a leading cause of global cancer‐related morbidity and mortality. This study examines the impact of first‐time screening colonoscopy on CRC incidence in obese individuals aged 75 and older using a la…
View article: Resmetirom for MASH: A Comprehensive Review of a Novel Therapeutic Frontier
Resmetirom for MASH: A Comprehensive Review of a Novel Therapeutic Frontier Open
Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease linked to type 2 diabetes (T2D), obesity, and dyslipidaemia, which are all parts of the metabolic syndrome. In 2024, for non-cirrhotic MASH with mild to…
View article: Comparative efficacy and safety of supine versus prone positioning in endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis
Comparative efficacy and safety of supine versus prone positioning in endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis Open
Background/Aims: Endoscopic retrograde cholangiopancreatography (ERCP) is conventionally performed in the prone position (PP). Recent studies have shown that the supine position (SP) is an effective alternative, with comparable success rat…
View article: Trends and disparities in human immunodeficiency virus and chronic liver disease mortality in the United States: A nationwide analysis
Trends and disparities in human immunodeficiency virus and chronic liver disease mortality in the United States: A nationwide analysis Open
Objectives With advances in antiretroviral therapy, the life expectancy of individuals living with human immunodeficiency virus infection has significantly improved. Consequently, non–acquired immunodeficiency syndrome-related conditions, …
View article: Optimizing Endoscopic Submucosal Dissection: A Meta-Analysis of the S–O Clip’s Impact on Procedural Outcomes and Lesion-Specific Applications
Optimizing Endoscopic Submucosal Dissection: A Meta-Analysis of the S–O Clip’s Impact on Procedural Outcomes and Lesion-Specific Applications Open
View article: Impact of <scp>COVID</scp>‐19 on Venous Thromboembolism in Inflammatory Bowel Disease Hospitalizations: A Propensity‐Matched Analysis
Impact of <span>COVID</span>‐19 on Venous Thromboembolism in Inflammatory Bowel Disease Hospitalizations: A Propensity‐Matched Analysis Open
Background and Aim Patients diagnosed with Inflammatory bowel disease (IBD) face a notably higher risk of venous thromboembolism (VTE), leading to significant health challenges. Similarly, coronavirus disease 2019 (COVID‐19) is associated …
View article: Navigating the Second Victim Experience in Gastrointestinal Endoscopy and Colonoscopy
Navigating the Second Victim Experience in Gastrointestinal Endoscopy and Colonoscopy Open
View article: A Systematic Review and Meta-Analysis of Liver Transplant Outcomes in Lean Versus Non-Lean Metabolic Dysfunction-Associated Steatotic Liver Disease Patients
A Systematic Review and Meta-Analysis of Liver Transplant Outcomes in Lean Versus Non-Lean Metabolic Dysfunction-Associated Steatotic Liver Disease Patients Open
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent hepatic disease with metabolic dysfunction-associated steatohepatitis (MASH) as its severe necro-inflammatory subtype. At present, it is the seco…
View article: Green Endoscopy: A Review of Global Perspectives on Environmental Sustainability of Gastrointestinal Endoscopy
Green Endoscopy: A Review of Global Perspectives on Environmental Sustainability of Gastrointestinal Endoscopy Open
Endoscopic procedures are the cornerstone of intervention in gastroenterology—from evaluating common illnesses to non-surgically managing complex diseases. Expectedly, these procedures are linked to greenhouse gas (GHG) emissions globally …
View article: Impact of Hospital Teaching Status on Outcomes of Acute Cholangitis: A Propensity-Matched Analysis of Hospitalizations in the United States
Impact of Hospital Teaching Status on Outcomes of Acute Cholangitis: A Propensity-Matched Analysis of Hospitalizations in the United States Open
Our study found higher mortality rates for AC patients in teaching hospitals compared to non-teaching hospitals. Teaching hospitals also had higher rates of septic shock, ICU admission, and intubation, with no difference in endoscopic retr…
View article: Endoscopic Management of Ampullary Adenomas: A Comprehensive Review
Endoscopic Management of Ampullary Adenomas: A Comprehensive Review Open
Ampullary adenomas are rare outgrowths at the ampulla of Vater that may progress into cancer via the adenoma-to-carcinoma sequence, particularly in individuals with hereditary polyposis syndrome. Many are diagnosed incidentally or once the…
View article: Updates and Current Knowledge on the Common Forms of Gastroenteritis: A Review
Updates and Current Knowledge on the Common Forms of Gastroenteritis: A Review Open
Background/Objective: Acute gastroenteritis is a major cause of diarrheal illnesses throughout the United States. The purpose of this article is to review the current knowledge in diagnostic and therapeutic aspects. Methods: A comprehensiv…
View article: Step by Step: A Meta-Analysis and Systematic Review on the Impact of Walking on Colonoscopy Outcomes
Step by Step: A Meta-Analysis and Systematic Review on the Impact of Walking on Colonoscopy Outcomes Open
Introduction: Colorectal cancer screening relies on effective bowel preparation before a colonoscopy. Walking has emerged as a potential adjunct strategy to achieve bowel cleansing prior to colonoscopy. We investigated the efficacy of walk…
View article: Frailty Predicts Mortality and Procedural Performance in Patients With Non‐Variceal Upper Gastrointestinal Bleeding
Frailty Predicts Mortality and Procedural Performance in Patients With Non‐Variceal Upper Gastrointestinal Bleeding Open
Introduction Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common cause of hospitalization in the United States, with approximately 400 000 admissions annually and a 5%–10% mortality rate. This study aimed to evaluate frailty's…
View article: Assessment of Lubiprostone as an Adjunct Therapy for Bowel Preparation in Colonoscopy: A Meta‐Analysis of Randomized Controlled Trials
Assessment of Lubiprostone as an Adjunct Therapy for Bowel Preparation in Colonoscopy: A Meta‐Analysis of Randomized Controlled Trials Open
Introduction The quality of bowel preparation has a significant impact on the success of colonoscopy. Currently, osmotically balanced polyethylene glycol electrolyte (PEG‐E) solutions are most commonly used for bowel preparation. Recently,…