Dwij Raj Bhatta
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View article: Trend in the Molecular Characterization and Geographic Distribution of Mycobacterium tuberculosis Complex Strains: A Systematic Review
Trend in the Molecular Characterization and Geographic Distribution of Mycobacterium tuberculosis Complex Strains: A Systematic Review Open
This systematic review aims to evaluate the global molecular characterization of Mycobacterium tuberculosis complex (MTBC) isolates from 2017 to June 2023, focusing on lineage distribution, drug resistance trends, and diagnostic methods. F…
View article: Advancing Molecular Insights: A Global Systematic Review and Meta-analysis of Epidemiology and Drug Resistance Patterns of Mycobacterium tuberculosis in Sputum Samples
Advancing Molecular Insights: A Global Systematic Review and Meta-analysis of Epidemiology and Drug Resistance Patterns of Mycobacterium tuberculosis in Sputum Samples Open
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of morbidity and mortality globally. The emergence of multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB) presents signif…
View article: mecA and PVL genes in methicillin-resistant Staphylococcus aureus from clinical specimens: a cross-sectional hospital based study from Nepal
mecA and PVL genes in methicillin-resistant Staphylococcus aureus from clinical specimens: a cross-sectional hospital based study from Nepal Open
Background and Objectives: Staphylococcus aureus has increasingly been associated with community and healthcare-as- sociated infections worldwide and contributes to treatment failures due to the emergence of multidrug-resistant (MDR) and m…
View article: Molecular characterization of rabies virus of Nepal
Molecular characterization of rabies virus of Nepal Open
A study was performed to identify the Rabies Virus genomes circulating in Nepal in 2009. Three brain samples, collected from carcass of buffalo, human and dog infected with Rabies were sent to Pasteur Institute, in France for molecular cha…
View article: Evaluation of Nitrate Reductase Assay For Rapid Detection of Drug Resistant Tuberculosis
Evaluation of Nitrate Reductase Assay For Rapid Detection of Drug Resistant Tuberculosis Open
Emergence of multidrug-resistant tuberculosis (MDR-TB) urgently demands for simple, rapid and inexpensive methods of its detection for the effective treatment of drug resistant tuberculosis, particularly in low-income countries. This prosp…
View article: Human skin bacterial flora differ with altitudes in different ethnic groups of Nepal
Human skin bacterial flora differ with altitudes in different ethnic groups of Nepal Open
Background: Largest organ of human body, the skin, is colonized by millions of microorganisms, most of which are not only harmless but also beneficial to the host. Human skin microbes depend upon geographical variations, ethnicity and vari…
View article: Antibacterial and Antifungal Property of Actinomycetes Isolates from Soil and Water of Nepal
Antibacterial and Antifungal Property of Actinomycetes Isolates from Soil and Water of Nepal Open
Background: Human pathogens are rapidly acquiring resistance to antibiotics leading to treatment failure. We carried out this study to isolate and screen actinomycetes strains that have potential to kill bacterial and fungal pathogens.Meth…
View article: Antibacterial and Antifungal Property of Actinomycetes Isolates from Soil and Water of Nepal
Antibacterial and Antifungal Property of Actinomycetes Isolates from Soil and Water of Nepal Open
Background: Human pathogens are rapidly acquiring resistance to antibiotics leading to treatment failure. We carried out this study to isolate and screen actinomycetes strains that have potential to kill bacterial and fungal pathogens. Met…
View article: Extended spectrum beta-lactamase and metallo beta-lactamase production among Escherichia coli and Klebsiella pneumoniae isolated from different clinical samples in a tertiary care hospital in Kathmandu, Nepal
Extended spectrum beta-lactamase and metallo beta-lactamase production among Escherichia coli and Klebsiella pneumoniae isolated from different clinical samples in a tertiary care hospital in Kathmandu, Nepal Open
High rate of ESBL production was found in the E. coli and K. pneumoniae isolated from outpatients suggesting the dissemination of ESBL producing isolates in community. This is very serious issue and can't be neglected. Regular monitoring o…
View article: Association of Panton Valentine Leukocidin (PVL) genes with methicillin resistant Staphylococcus aureus (MRSA) in Western Nepal: a matter of concern for community infections (a hospital based prospective study)
Association of Panton Valentine Leukocidin (PVL) genes with methicillin resistant Staphylococcus aureus (MRSA) in Western Nepal: a matter of concern for community infections (a hospital based prospective study) Open
View article: Molecular epidemiology of rabies virus in Nepal
Molecular epidemiology of rabies virus in Nepal Open
Background: Rabies is endemic and priority zoonotic disease in Nepal. Death of 150 people and 200 animals has been reported annually in this country however molecular epidemiology of rabies has not been well understood. A study was perform…
View article: Detection of Anti-<i>Leptospira</i>IgM Antibody in Serum Samples of Suspected Patients Visiting National Public Health Laboratory, Teku, Kathmandu
Detection of Anti-<i>Leptospira</i>IgM Antibody in Serum Samples of Suspected Patients Visiting National Public Health Laboratory, Teku, Kathmandu Open
Leptospirosis is a globally distributed zoonosis with varied clinical outcomes and multiorgan involvement in humans. In this study conducted from July 2011 to December 2011, 178 serum samples from patients suspected of leptospirosis were t…
View article: Threat of multidrug resistant Staphylococcus aureus in Western Nepal
Threat of multidrug resistant Staphylococcus aureus in Western Nepal Open
ObjectiveTo determine the prevalence of methicillin resistant Staphylococcus aureus (MRSA) and antimicrobial susceptibility patterns of the isolates from Manipal Teaching Hospital, Pokhara, Nepal. MethodsThis study was conducted over a per…
View article: Phenotypic Detection of Carbapenemases and β-lactamases induced Carbapenem Resistance in Enterobacteriaceae
Phenotypic Detection of Carbapenemases and β-lactamases induced Carbapenem Resistance in Enterobacteriaceae Open
Carbapenem-resistant Enterobacteriaceae has challenged the therapeutic efficacy and raised the most worrisome global issue of public health importance. The study was conducted to determine the burden of carbapenem resistant isolates of Ent…
View article: Nosocomial Isolates and Their Drug Resistant Pattern in ICU Patients at National Institute of Neurological and Allied Sciences, Nepal
Nosocomial Isolates and Their Drug Resistant Pattern in ICU Patients at National Institute of Neurological and Allied Sciences, Nepal Open
Multidrug resistant organisms are increasing day by day and the cause is poorly known. This study was carried out from June 2011 to May 2012 at National Institute of Neurological and Allied Sciences Kathmandu, Nepal, with a view to determi…