Dena S. Davis
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View article: Co-crystal structure of <i>Helicobacter pylori</i> biotin protein ligase with biotinyl-5-ATP
Co-crystal structure of <i>Helicobacter pylori</i> biotin protein ligase with biotinyl-5-ATP Open
Helicobacter pylori , a type 1 carcinogen that causes human gastric ulcers and cancer, is a priority target of the Seattle Structural Genomics Center for Infectious Disease (SSGCID). These efforts include determining the structures of pote…
View article: Crystal structure of glutamyl-tRNA synthetase from <i>Helicobacter pylori</i>
Crystal structure of glutamyl-tRNA synthetase from <i>Helicobacter pylori</i> Open
Helicobacter pylori is one of the most common bacterial infections; over two-thirds of the world's population is infected by early childhood. Persistent H. pylori infection results in gastric ulcers and cancers. Due to drug resistance, the…
View article: Response to Stanley Terman: Too little, too late
Response to Stanley Terman: Too little, too late Open
A recent study quantified what a lot of us already know: Alzheimer's disease (AD) has surpassed cancer as the disease Americans fear most. 1 The reason is obvious: Whereas cancer brings fear of pain, death, and financial stress, one is cog…
View article: 47 Two cheers for choosing wisely: a consumer perspective
47 Two cheers for choosing wisely: a consumer perspective Open
Choosing Wisely's effectiveness has been disappointing, and commentators are asking where it misses the boat. This presentation critiques the Choosing Wisely project from the perspective of a healthcare consumer who tried to use it. When …
View article: Investigation of the IEC Safety Standard for Small Wind Turbine Design Through Modeling and Testing: Preprint
Investigation of the IEC Safety Standard for Small Wind Turbine Design Through Modeling and Testing: Preprint Open
Since 1999, the International Electrotechnical Commission (IEC) Maintenance Team 2 (MT2) has been working on a revision of the IEC 61400-2 standard on the safety, quality, integrity, and design requirements of small wind turbines (SWTs). D…
View article: Ethical Controversy About Hysterectomy for a Minor
Ethical Controversy About Hysterectomy for a Minor Open
One of the most complicated ethical issues that arises in children’s hospitals today is the issue of whether it is ever permissible to perform a procedure for a minor that will result in permanent sterilization. In most cases, the answer i…