Dylan Sérillon
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View article: Highlighting the Major Role of Cyclin C in Cyclin-Dependent Kinase 8 Activity through Molecular Dynamics Simulations
Highlighting the Major Role of Cyclin C in Cyclin-Dependent Kinase 8 Activity through Molecular Dynamics Simulations Open
Dysregulation of cyclin-dependent kinase 8 (CDK8) activity has been associated with many diseases, including colorectal and breast cancer. As usual in the CDK family, the activity of CDK8 is controlled by a regulatory protein called cyclin…
View article: Highlighting the Major Role of Cyclin C on Cyclin-Dependent Kinase 8 Activity by Molecular Dynamics Simulations
Highlighting the Major Role of Cyclin C on Cyclin-Dependent Kinase 8 Activity by Molecular Dynamics Simulations Open
Dysregulation of the Cyclin-dependent kinase 8 (CDK8) activity has been associated to many diseases including the colorectal and breast cancer. As usual in the CDK family, the activity of CDK8 is controlled by a regulatory protein called c…
View article: Multi-Responsive Eight-State Bis(acridinium-Zn(II) porphyrin) Receptor
Multi-Responsive Eight-State Bis(acridinium-Zn(II) porphyrin) Receptor Open
A multi-responsive receptor consisting of two (acridinium-Zn(II) porphyrin) conjugates has been designed. The binding constant between this receptor and a ditopic guest has been modulated (i) upon addition of nucleophiles converting acridi…
View article: Computational exploration of host-guest complexes
Computational exploration of host-guest complexes Open
Supramolecular chemistry has experienced enormous growth in recent years. Supramolecular processes and, in particular, host-guest interactions are studied for the variety of their potential applications (from industrial processes to medica…
View article: Synthesis, electronic and photophysical properties of a bisacridinium-Zn(II) porphyrin conjugate
Synthesis, electronic and photophysical properties of a bisacridinium-Zn(II) porphyrin conjugate Open
The synthesis of a novel bisacridinium-Zn(II) porphyrin is reported and its properties investigated via electrochemical, photophysical and computational studies. Cyclic voltammetry studies revealed a two-electron oxidation of the Zn(II) po…
View article: Synthesis, electronic and photophysical properties of a bisacridinium-Zn(II) porphyrin conjugate
Synthesis, electronic and photophysical properties of a bisacridinium-Zn(II) porphyrin conjugate Open
The synthesis of a novel bisacridinium-Zn(II) porphyrin is reported and its properties investigated via electrochemical, photophysical and computational studies. Cyclic voltammetry studies revealed a two-electron oxidation of the Zn(II) po…