Dylan Sweetman
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View article: Correction: Effects of insulin like growth factors on early embryonic chick limb myogenesis
Correction: Effects of insulin like growth factors on early embryonic chick limb myogenesis Open
[This corrects the article DOI: 10.1371/journal.pone.0185775.].
View article: Effects of insulin like growth factors on early embryonic chick limb myogenesis
Effects of insulin like growth factors on early embryonic chick limb myogenesis Open
Limb muscles derive from pax3 expressing precursor cells that migrate from the hypaxial somite into the developing limb bud. Once there they begin to differentiate and express muscle determination genes such as MyoD. This process is regula…
View article: Epigenetics and developmental programming of welfare and production traits in farm animals
Epigenetics and developmental programming of welfare and production traits in farm animals Open
The concept that postnatal health and development can be influenced by events that occur in utero originated from epidemiological studies in humans supported by numerous mechanistic (including epigenetic) studies in a variety of model spec…
View article: Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression Open
Using chicken embryos it is possible to test directly the effects of either growth factors or specific inhibitors of signaling pathways on gene expression and activation of signal transduction pathways. This technique allows the delivery o…
View article: Expression of myogenic regulatory factors in chicken embryos during somite and limb development
Expression of myogenic regulatory factors in chicken embryos during somite and limb development Open
The expression of the myogenic regulatory factors (MRFs), Myf5 , MyoD, myogenin ( Mgn ) and MRF4 have been analysed during the development of chicken embryo somites and limbs. In somites, Myf5 is expressed first in somites and paraxial mes…
View article: Actin Depolymerization Is Associated with Meiotic Acceleration in Cycloheximide-Treated Ovine Oocytes1
Actin Depolymerization Is Associated with Meiotic Acceleration in Cycloheximide-Treated Ovine Oocytes1 Open
Oocytes treated with the protein synthesis inhibitor cycloheximide (CHX) arrest at the germinal vesicle (GV) stage and undergo accelerated GV breakdown (GVBD) after CHX is removed. However, little is known about the underlying mechanism of…