Dylan Wolman
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View article: Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy
Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy Open
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with altepl…
View article: Prolonged Venous Transit on Perfusion Imaging: An Evolving Marker of Outcomes in Large Vessel Occlusion Stroke – A Comprehensive Review
Prolonged Venous Transit on Perfusion Imaging: An Evolving Marker of Outcomes in Large Vessel Occlusion Stroke – A Comprehensive Review Open
Stroke remains a leading cause of death and disability worldwide, with anterior circulation large-vessel occlusion (AIS-LVO) representing a major contributor. While arterial parameters such as cerebral blood flow (CBF), cerebral blood volu…
View article: Prolonged Venous Transit Is Associated with Unfavorable Functional Outcomes in Large Core Stroke
Prolonged Venous Transit Is Associated with Unfavorable Functional Outcomes in Large Core Stroke Open
PVT is independently associated with unfavorable outcomes in patients with large core AIS-LVO. These findings suggest PVT may serve as a prognostic marker, warranting further investigation and validation in larger prospective studies to gu…
View article: Unfavorable Perfusion Collateral Impairment Score Is Associated with Higher Odds of Poor Outcomes in Large Vessel Occlusion Stroke
Unfavorable Perfusion Collateral Impairment Score Is Associated with Higher Odds of Poor Outcomes in Large Vessel Occlusion Stroke Open
BACKGROUND Effective collateral circulation significantly influences clinical outcomes in patients with acute ischemic stroke due to large vessel occlusion. We developed and evaluated a composite Perfusion Collateral Impairment Score (PCIS…
View article: Integrating perfusion imaging derived venous outflow and tissue-level collateral parameters in a comprehensive clinical model enhances prognostication in large vessel occlusion stroke
Integrating perfusion imaging derived venous outflow and tissue-level collateral parameters in a comprehensive clinical model enhances prognostication in large vessel occlusion stroke Open
Arterial inflow restoration and collateral status have been significantly correlated with functional outcomes in AIS-LVO patients undergoing mechanical thrombectomy (MT). CT perfusion imaging biomarkers, including prolonged venous transit …
View article: Characterizing Liquid Embolic Distribution and Its Impact on Chronic Subdural Hematoma Outcomes following Middle Meningeal Artery Embolization
Characterizing Liquid Embolic Distribution and Its Impact on Chronic Subdural Hematoma Outcomes following Middle Meningeal Artery Embolization Open
We present a framework for characterizing the appearance of liquid embolic agents after MMAE. Visualized membrane penetration during angiography was associated with greater and faster cSDH resorption and higher odds of complete resolution.…
View article: Prolonged Venous Transit as a Superior Predictor of Functional Outcomes in Successfully Reperfused Large Vessel Occlusions: Comparative Analysis With Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio
Prolonged Venous Transit as a Superior Predictor of Functional Outcomes in Successfully Reperfused Large Vessel Occlusions: Comparative Analysis With Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio Open
Background Collateral status plays a crucial role in outcomes after acute ischemic stroke due to large vessel occlusion. Tissue‐level collaterals and venous outflow are key components following mechanical thrombectomy. This study evaluates…
View article: Mechanical thrombectomy for acute ischemic stroke performed without continuous saline flushes and using moderate sedation: The TOOFAST technique
Mechanical thrombectomy for acute ischemic stroke performed without continuous saline flushes and using moderate sedation: The TOOFAST technique Open
Background Rapid reperfusion is an important predictor of neurologic recovery in acute ischemic stroke due to large vessel occlusion (AIS-LVO) treated with mechanical thrombectomy (MT). We present a single-institution retrospective observa…
View article: Predictors of Skilled Nursing Facility Length of Stay and Discharge After Aneurysmal Subarachnoid Hemorrhage
Predictors of Skilled Nursing Facility Length of Stay and Discharge After Aneurysmal Subarachnoid Hemorrhage Open
Background and Purpose Aneurysmal subarachnoid hemorrhage (aSAH) carries high morbidity and mortality with survivors often requiring extended care at skilled nursing facilities (SNF). Predictors of SNF discharge to home (SNFdcH) remain unc…
View article: Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion
Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion Open
Background Acute ischaemic stroke (AIS) is a leading cause of mortality and disability globally, with volume contracted state (VCS), as indicated by an elevated blood urea nitrogen to creatinine (BUN/Cr) ratio, potentially influencing outc…
View article: Emergent Endovascular Intervention for Acute Neurological Deficits Post-Carotid Endarterectomy: A Single-Institutional Analysis and Systematic Review of the Literature
Emergent Endovascular Intervention for Acute Neurological Deficits Post-Carotid Endarterectomy: A Single-Institutional Analysis and Systematic Review of the Literature Open
EVT is likely a technically viable alternative treatment for patients with perioperative acute neurologic deficits after CEA. However, most of the literature available comes from case series, thereby limiting the quality of evidence. Impro…
View article: Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large‐vessel occlusion stroke
Prolonged venous transit is associated with lower odds of excellent recovery after reperfusion in anterior large‐vessel occlusion stroke Open
Background and purpose Acute ischemic stroke due to anterior circulation large‐vessel occlusion (AIS‐LVO) remains a leading cause of disability despite successful reperfusion therapies. Prolonged venous transit (PVT) has emerged as a poten…
View article: Prolonged Venous Transit on Perfusion Imaging Is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions
Prolonged Venous Transit on Perfusion Imaging Is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions Open
In successfully reperfused large vessel occlusion strokes, PVT+ was associated with an additional 2 days of hospital stay on average compared with PVT- patients, when adjusting for other clinical covariables. This simple, novel imaging met…
View article: Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke
Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke Open
In patients with anterior circulation DMVO, a higher CBV index on pretreatment CTP is an independent predictor of excellent functional outcomes at 90 days. These findings suggest that CTP parameters, particularly the CBV index, may be usef…
View article: Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes
Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes Open
Objective Venous outflow (VO) impairment predicts unfavorable outcomes in patients with acute ischemic stroke caused by large vessel occlusion (AIS‐LVO). Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) …
View article: Treatment of Spontaneous Subarachnoid Hemorrhage: A 20‐Year National Inpatient Sample Review
Treatment of Spontaneous Subarachnoid Hemorrhage: A 20‐Year National Inpatient Sample Review Open
Background Aneurysmal subarachnoid hemorrhage (aSAH) is a major source of morbidity and mortality, and its management has undergone foundational changes over thepast 2 decades. We reviewed the National Inpatient Sample to outline the chang…
View article: Dual-Energy CTA Iodine Map Reconstructions Improve Visualization of Residual Cerebral Aneurysms following Endovascular Coiling
Dual-Energy CTA Iodine Map Reconstructions Improve Visualization of Residual Cerebral Aneurysms following Endovascular Coiling Open
MIP IM-DECTA can subtract coil mass artifact and is more sensitive and specific than CCTA for the detection of residual aneurysms after endovascular coiling.
View article: Treatment of Spontaneous Subarachnoid Hemorrhage: A 20-year National Inpatient Sample Review
Treatment of Spontaneous Subarachnoid Hemorrhage: A 20-year National Inpatient Sample Review Open
Background Aneurysmal subarachnoid hemorrhage is a major source of morbidity and mortality, and its management has undergone foundational changes over the last 2 decades. We reviewed the National Inpatient Sample (NIS) to outline the chang…
View article: Detection of Early Ischemic Changes with Virtual Noncontrast Dual-Energy CT in Acute Ischemic Stroke: A Noninferiority Analysis
Detection of Early Ischemic Changes with Virtual Noncontrast Dual-Energy CT in Acute Ischemic Stroke: A Noninferiority Analysis Open
Dual-energy virtual NCCT is noninferior compared with conventional NCCT for the detection of early ischemic changes with ASPECTS.
View article: Image Quality of Virtual Monochromatic Reconstructions of Noncontrast CT on a Dual-Source CT Scanner in Adult Patients
Image Quality of Virtual Monochromatic Reconstructions of Noncontrast CT on a Dual-Source CT Scanner in Adult Patients Open
Optimal image quality of VMI energies can improve brain parenchymal image quality compared to conventional CT but are reconstruction kernel dependent and depend on indication for performing noncontrast CT.