Eduard-Alexandru Bonci
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View article: Equitable colorectal cancer screening implementation framework via a modified Delphi Consensus for Romanian healthcare
Equitable colorectal cancer screening implementation framework via a modified Delphi Consensus for Romanian healthcare Open
View article: A core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials
A core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials Open
Accurate information about locoregional breast cancer treatments following neoadjuvant systemic therapy (NST) is essential for meaningful interpretation of oncological outcomes but reporting is currently poor. We developed a core outcome s…
View article: European Society of Surgical Oncology Young Surgeons (Young ESSO): A path for training excellence, inclusive leadership and research engagement
European Society of Surgical Oncology Young Surgeons (Young ESSO): A path for training excellence, inclusive leadership and research engagement Open
View article: BreLoAI - A Scalable Web Application for Breast Cancer Locoregional Treatment Approaches
BreLoAI - A Scalable Web Application for Breast Cancer Locoregional Treatment Approaches Open
View article: Lost axillary markers after neoadjuvant chemotherapy in breast cancer patients - data from the prospective international AXSANA (EUBREAST 3) cohort study (NCT04373655)
Lost axillary markers after neoadjuvant chemotherapy in breast cancer patients - data from the prospective international AXSANA (EUBREAST 3) cohort study (NCT04373655) Open
View article: Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study
Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study Open
Background There is low-certainty evidence on the impact of extended pharmacological prophylaxis on venous thromboembolism-associated morbidity and mortality. The aim of this study was to determine the efficacy and safety of extended proph…
View article: Commentary and Updates on the Management of Male Breast Cancer
Commentary and Updates on the Management of Male Breast Cancer Open
View article: Association of Axillary Lymph Node Dissection with Oncological Outcomes in Patients with Residual Micrometastases after Neoadjuvant Chemotherapy: The OPBC-07/microNAC Study
Association of Axillary Lymph Node Dissection with Oncological Outcomes in Patients with Residual Micrometastases after Neoadjuvant Chemotherapy: The OPBC-07/microNAC Study Open
View article: A multidisciplinary team and patient perspective on omission of surgery after neoadjuvant systemic therapy for early breast cancer: A European Society of Surgical Oncology (ESSO) Research Academy survey
A multidisciplinary team and patient perspective on omission of surgery after neoadjuvant systemic therapy for early breast cancer: A European Society of Surgical Oncology (ESSO) Research Academy survey Open
View article: Pneumocystis jirovecii Pneumonia Infection in Breast Cancer Receiving Dose-dense Chemotherapy: A Case Report and Literature Review
Pneumocystis jirovecii Pneumonia Infection in Breast Cancer Receiving Dose-dense Chemotherapy: A Case Report and Literature Review Open
We herein report 3 cases of breast cancer who developed Pneumocystis Jirovecii Pneumonia during dose-dense chemotherapy. The patients developed fever, fatigue, and cough on the 4th to 5th cycle of chemotherapy. Chest computed tomography (C…
View article: The Expression of Forkhead Box P3 T Regulatory Lymphocytes as a Prognostic Factor in Malignant Melanomas
The Expression of Forkhead Box P3 T Regulatory Lymphocytes as a Prognostic Factor in Malignant Melanomas Open
Since transcription factor Forkhead Box P3 (FoxP3) was identified as a specific regulatory T cell (Treg) marker, researchers have scrutinized its value as a potential novel therapeutic target or a prognostic factor in various types of canc…
View article: Sometimes it is better to just make it simple. De-escalation of oncoplastic and reconstructive procedures
Sometimes it is better to just make it simple. De-escalation of oncoplastic and reconstructive procedures Open
Simple breast conservation surgery (sBCS) has technically advanced onto oncoplastic breast procedures (OBP) to avoid mastectomy and improve breast cancer patients' psychosocial well-being and cosmetic outcome. Although OBP are time-consumi…
View article: The Role of miR-375-3p, miR-210-3p and Let-7e-5p in the Pathological Response of Breast Cancer Patients to Neoadjuvant Therapy
The Role of miR-375-3p, miR-210-3p and Let-7e-5p in the Pathological Response of Breast Cancer Patients to Neoadjuvant Therapy Open
Background and Objectives: Prediction of response to therapy remains a continuing challenge in treating breast cancer, especially for identifying molecular tissue markers that best characterize resistant tumours. Microribonucleic acids (mi…
View article: 2022-RA-1614-ESGO Impact of various cervical cancer treatments on sexual functioning and quality of life of women: a systematic review and meta-analysis
2022-RA-1614-ESGO Impact of various cervical cancer treatments on sexual functioning and quality of life of women: a systematic review and meta-analysis Open
View article: 2022-RA-437-ESGO Meta-analyses reveal serum or plasma interleukin-6 as a biomarker for malignant ovarian neoplasia
2022-RA-437-ESGO Meta-analyses reveal serum or plasma interleukin-6 as a biomarker for malignant ovarian neoplasia Open
View article: Anterolateral thigh flap for abdominal wall reconstruction. A case report
Anterolateral thigh flap for abdominal wall reconstruction. A case report Open
Abdominal wall reconstruction aims at restoring the anatomical, functional and aesthetic integrity of this region, while providing protection of abdominal viscera and prevent herniation. There are various techniques used for abdominal wall…
View article: The Role of Circulating Tumor Cells in the Prognosis of Metastatic Triple-Negative Breast Cancers: A Systematic Review of the Literature
The Role of Circulating Tumor Cells in the Prognosis of Metastatic Triple-Negative Breast Cancers: A Systematic Review of the Literature Open
Breast cancer is one of the leading causes of death in women worldwide. One subtype of breast cancer is the triple-negative, which accounts for 15% of total breast cancer cases and is known for its poor prognosis. The main cause of death i…
View article: Prognostic factors for in-transit metastasis in patients with malignant melanoma
Prognostic factors for in-transit metastasis in patients with malignant melanoma Open
Background and aims. Malignant melanoma represents an aggressive and unpredictable malignancy, with high locoregional recurrence rates, regardless of tumor stage and therapeutic management. This study aims to identify the main histopatholo…
View article: Vitamin D Supplementation: Oxidative Stress Modulation in a Mouse Model of Ovalbumin-Induced Acute Asthmatic Airway Inflammation
Vitamin D Supplementation: Oxidative Stress Modulation in a Mouse Model of Ovalbumin-Induced Acute Asthmatic Airway Inflammation Open
Asthma oxidative stress disturbances seem to enable supplementary proinflammatory pathways, thus contributing to disease development and severity. The current study analyzed the impact of two types of oral vitamin D (VD) supplementation re…
View article: Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study
Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowledge Gaps, and Rationale for the EUBREAST-03 AXSANA Study Open
In the last two decades, surgical methods for axillary staging in breast cancer patients have become less extensive, and full axillary lymph node dissection (ALND) is confined to selected patients. In initially node-positive patients under…
View article: Does Surgical Margin Width Remain a Challenge for Triple-Negative Breast Cancer? A Retrospective Analysis
Does Surgical Margin Width Remain a Challenge for Triple-Negative Breast Cancer? A Retrospective Analysis Open
Background and Objectives: Local and distant relapse (LR, DR) in breast cancer vary according to its molecular subtypes, with triple-negative breast cancer (TNBC) being the most aggressive. The surgical resection margin width (SRMW) for br…
View article: The Role of Circulating Tumor Cells in Chemoresistant Metastatic Breast Cancer
The Role of Circulating Tumor Cells in Chemoresistant Metastatic Breast Cancer Open
Breast cancer is the most frequent form of cancer among women and is one of the leading causes of death. Two routes of the metastatic process have been described: linear and parallel progression. A key factor is represented by circulating …
View article: What we learned in axillary management of breast cancer patients at the American society of clinical oncology (ASCO) 2020 virtual meeting? The EUBREAST point of view
What we learned in axillary management of breast cancer patients at the American society of clinical oncology (ASCO) 2020 virtual meeting? The EUBREAST point of view Open
View article: MicroRNA in Papillary Thyroid Carcinoma: A Systematic Review from 2018 to June 2020
MicroRNA in Papillary Thyroid Carcinoma: A Systematic Review from 2018 to June 2020 Open
The involvement of micro-ribonucleic acid (microRNAs) in metabolic pathways such as regulation, signal transduction, cell maintenance, and differentiation make them possible biomarkers and therapeutic targets. The purpose of this review is…
View article: Suboptimal Serum 25-Hydroxy-Vitamin D Is Associated with a History of Recent Disease Exacerbation in Pediatric Patients with Bronchial Asthma or Asthma-Suggestive Recurrent Wheezing
Suboptimal Serum 25-Hydroxy-Vitamin D Is Associated with a History of Recent Disease Exacerbation in Pediatric Patients with Bronchial Asthma or Asthma-Suggestive Recurrent Wheezing Open
Even though vitamin D is widely acknowledged as having a potential immunomodulatory role in asthma, its exact beneficial mechanisms are yet to be clarified. An optimal serum 25-hydroxy-vitamin D (25-OH-VitD) level in pediatric asthma patie…
View article: Reply to “Missing Skeletal Muscle Metastases of Papillary Thyroid Carcinoma”
Reply to “Missing Skeletal Muscle Metastases of Papillary Thyroid Carcinoma” Open
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View article: A Mathematical Model of the Transition from Normal Hematopoiesis to the Chronic and Accelerated-Acute Stages in Myeloid Leukemia
A Mathematical Model of the Transition from Normal Hematopoiesis to the Chronic and Accelerated-Acute Stages in Myeloid Leukemia Open
A mathematical model given by a two-dimensional differential system is introduced in order to understand the transition process from the normal hematopoiesis to the chronic and accelerated-acute stages in chronic myeloid leukemia. A previo…
View article: Post-Treatment Thyroid Diseases in Children with Brain Tumors: A Single-Center Experience at “Prof. Dr. Ion Chiricuță” Institute of Oncology, Cluj-Napoca
Post-Treatment Thyroid Diseases in Children with Brain Tumors: A Single-Center Experience at “Prof. Dr. Ion Chiricuță” Institute of Oncology, Cluj-Napoca Open
Aim of study: The purpose of the study was to evaluate the association of thyroid dysfunction occurring in pediatric patients treated for brain tumors. Patients and methods: A total of 255 patients with brain tumors were treated between 20…
View article: Skeletal Muscle Metastasis in Papillary Thyroid Microcarcinoma Evaluated by F18-FDG PET/CT
Skeletal Muscle Metastasis in Papillary Thyroid Microcarcinoma Evaluated by F18-FDG PET/CT Open
Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy and is characterized by slow growth and an indolent biological behavior. Papillary thyroid microcarcinoma is the PTC with the maximum size of the tumor <1cm, cons…
View article: A Mathematical Model of the Transition from the Normal Hematopoiesis to the Chronic and Accelerated Acute Stages in Myeloid Leukemia
A Mathematical Model of the Transition from the Normal Hematopoiesis to the Chronic and Accelerated Acute Stages in Myeloid Leukemia Open
A mathematical model given by a two - dimensional differential system is introduced in order to understand the transition process from the normal hematopoiesis to the chronic and accelerated acute stages in chronic myeloid leukemia. A prev…