William E. Butler
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View article: MYB Alterations in Angiocentric Gliomas
MYB Alterations in Angiocentric Gliomas Open
We performed a systematic review of the literature to better define the scope of MYB alterations in angiocentric glioma and their associated clinical characteristics, as well as to include a novel MYB mutation in an angiocentric glioma cas…
View article: <scp>CoCare</scp> ‐ <scp>CI</scp> : A Clinical Innovation to Address Behavioral Symptoms in Hospitalized Older Adults With Cognitive Impairment
<span>CoCare</span> ‐ <span>CI</span> : A Clinical Innovation to Address Behavioral Symptoms in Hospitalized Older Adults With Cognitive Impairment Open
Introduction Behavioral symptoms in hospitalized older adults with cognitive impairment often lead to physical and chemical restraint use, despite associated harms. Patient‐centered care models show promise in reducing restraint use but ar…
View article: Benchmark Workshop on Selected Deep-Sea Fisheries Stocks (WKBDEEP)
Benchmark Workshop on Selected Deep-Sea Fisheries Stocks (WKBDEEP) Open
The objective of this benchmark process was to propose and evaluate assessment methods and the data upon which they depend for the three stocks: Greater silver smelt in Division 5a and Subarea 14 (aru.27.5a14), Blue ling in Division 5a and…
View article: Algebraic Nexus of Fibonacci Forms and Two-Simplex Topology in Multicellular Morphogenesis
Algebraic Nexus of Fibonacci Forms and Two-Simplex Topology in Multicellular Morphogenesis Open
Background: Fibonacci patterns and tubular forms both arose early in the phylogeny of multicellular organisms. Tubular forms offer the advantage of a regulated internal milieu, and Fibonacci forms may offer packing efficiencies. The underl…
View article: Rapid and Sensitive Detection of Fentanyl and Its Analogs by a Novel Chemiluminescence Immunoassay
Rapid and Sensitive Detection of Fentanyl and Its Analogs by a Novel Chemiluminescence Immunoassay Open
Background Abuse of fentanyl and its analogs is a major contributor to the opioid overdose epidemic in the United States, but detecting and quantifying trace amounts of such drugs remains a challenge without resorting to sophisticated mass…
View article: Algebraic Nexus of Fibonacci Forms and 2-Simplex Topology in Multicellular Morphogenesis
Algebraic Nexus of Fibonacci Forms and 2-Simplex Topology in Multicellular Morphogenesis Open
Background: Fibonacci patterns and tubular forms both arose early in the phylogeny of multicellular organisms. Tubular forms offer the advantage of a regulated internal milieu, and Fibonacci forms may offer packing efficiencies. The underl…
View article: Rapid and Highly Sensitive Detection of Fentanyl and its Analogs by a Novel Chemiluminescence Immunoassay
Rapid and Highly Sensitive Detection of Fentanyl and its Analogs by a Novel Chemiluminescence Immunoassay Open
A highly sensitive immunoassay with sub-picogram limit of detection for fentanyl and a wide range of fentanyl analogs has been developed, using a novel high affinity antibody fused with NanoLuc, a small-size luciferase that can emit strong…
View article: O-030 Arteriovenous coherence: a potential novel parameter for quantifying AVM hemodynamics using wavelet brain angiography
O-030 Arteriovenous coherence: a potential novel parameter for quantifying AVM hemodynamics using wavelet brain angiography Open
Background Quantifiable parameters that can capture the hemodynamic profile of an AVM are lacking, as current methods of AVM assessment are descriptive. Recently, we have established a novel computational method to analyze vascular pulse w…
View article: Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations
Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations Open
To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common and severe congenital brain arteriovenous malformation, we performed an integrated analysis of 310 VOGM proband-family exomes and 336,326 human cerebrova…
View article: Rethinking the cilia hypothesis of hydrocephalus
Rethinking the cilia hypothesis of hydrocephalus Open
Dysfunction of motile cilia in ependymal cells has been proposed to be a pathogenic cause of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in hydrocephalus, primarily based on observations of enlarged ventricl…
View article: A neural stem cell paradigm of pediatric hydrocephalus
A neural stem cell paradigm of pediatric hydrocephalus Open
Pediatric hydrocephalus, the leading reason for brain surgery in children, is characterized by enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) overaccumulation. Neurosurgical shunting to reduce CS…
View article: Rewiring of the N-Glycome with Prostate Cancer Progression and Therapy Resistance
Rewiring of the N-Glycome with Prostate Cancer Progression and Therapy Resistance Open
An understanding of the molecular features associated with prostate cancer progression (PCa) and resistance to hormonal therapy is crucial for the identification of new targets that can be utilized to treat advanced disease and prolong pat…
View article: Angiographic Pulse Wave Coherence in the Human Brain
Angiographic Pulse Wave Coherence in the Human Brain Open
A stroke volume of arterial blood that arrives to the brain housed in the rigid cranium must be matched over the cardiac cycle by an equivalent volume of ejected venous blood. We hypothesize that the brain maintains this equilibrium by org…
View article: Angiography Pulse Wave Coherence Data
Angiography Pulse Wave Coherence Data Open
Human angiography data. The file naming convention is Subject.Projection.DataType.h5. There are 4 human subjects. The data are anonymized. The study was approved by the Massachusetts General Hospital ethics committee. The same cardiac sign…
View article: Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus Open
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and failure rat…
View article: Guest Editor’s Note – Some Reflections on Integration in Eurasia
Guest Editor’s Note – Some Reflections on Integration in Eurasia Open
In this prefatory article the author surveys the general concept of “integration” and its development and application in Soviet and post-Soviet space and then reviews the particular contributions made by each article contributed to this sp…
View article: 150th anniversary of professor M. A. Taube: years of development and triumph, oblivion and renaissance
150th anniversary of professor M. A. Taube: years of development and triumph, oblivion and renaissance Open
This article discusses the life and work of a talented Russian legal scholar and international
\nlawyer, an authoritative public and political figure of the late 19th — first half of 20nd centuries,
\nProfessor of St. Petersburg University…
View article: Ring shape Golden Ratio multicellular structures are algebraically afforded by asymmetric mitosis and one to one cell adhesion
Ring shape Golden Ratio multicellular structures are algebraically afforded by asymmetric mitosis and one to one cell adhesion Open
Golden Ratio proportions are found throughout the world of multicellular organisms but the underlying mechanisms behind their appearance and their adaptive value if any remain unknown. The Golden Ratio is a real-valued number but cell popu…
View article: Review of: Marochkin S. Yu. The Operation of International law in the Russian Legal System: A Changing Approach. Leiden; Boston: Brill, Nijhoff, 2019. 308 p.
Review of: Marochkin S. Yu. The Operation of International law in the Russian Legal System: A Changing Approach. Leiden; Boston: Brill, Nijhoff, 2019. 308 p. Open
The review analyzes the work by Professor S. Yu. Marochkin, The Operation of International Law
\nin the Russian Legal System: A Changing Approach, published in 2019 by the European-American publishing house “Brill, Nijhoff.” This is an unc…
View article: Wavelet brain angiography suggests arteriovenous pulse wave phase locking
Wavelet brain angiography suggests arteriovenous pulse wave phase locking Open
When a stroke volume of arterial blood arrives to the brain, the total blood volume in the bony cranium must remain constant as the proportions of arterial and venous blood vary, and by the end of the cardiac cycle an equivalent volume of …
View article: CSF in the ventricles of the brain behaves as a relay medium for arteriovenous pulse wave phase coupling
CSF in the ventricles of the brain behaves as a relay medium for arteriovenous pulse wave phase coupling Open
The ventricles of the brain remain perhaps the largest anatomic structure in the human body without established primary purpose, even though their existence has been known at least since described by Aristotle. We hypothesize that the vent…
View article: Flow diversion of a recurrent, iatrogenic basilar tip aneurysm in a pediatric patient: case report
Flow diversion of a recurrent, iatrogenic basilar tip aneurysm in a pediatric patient: case report Open
Endoscopic third ventriculostomy (ETV) is a common treatment for noncommunicating hydrocephalus. Although rare, vascular injury and traumatic pseudoaneurysm development during ETV have been reported. The authors present the case of a 13-ye…
View article: Select bibliography
Select bibliography Open
Coalmining was a notoriously dangerous industry and many of its workers experienced injury and disease. However, the experiences of the many disabled people within Britain's most dangerous industry have gone largely unrecognised by histori…
View article: List of abbreviations
List of abbreviations Open
Coalmining was a notoriously dangerous industry and many of its workers experienced injury and disease. However, the experiences of the many disabled people within Britain's most dangerous industry have gone largely unrecognised by histori…