Anna Combes
YOU?
Author Swipe
View article: Relaxation-compensated chemical exchange saturation transfer MRI in the cervical spinal cord at 3T: An application in multiple sclerosis
Relaxation-compensated chemical exchange saturation transfer MRI in the cervical spinal cord at 3T: An application in multiple sclerosis Open
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system, characterized by demyelination. Exploring pathological changes in the spinal cord could improve our understanding of the mechanisms that cause neurologi…
View article: Leveling up: along-level diffusion tensor imaging in the spinal cord of multiple sclerosis patients
Leveling up: along-level diffusion tensor imaging in the spinal cord of multiple sclerosis patients Open
Introduction Multiple sclerosis (MS) is a chronic neuroinflammatory disease marked by demyelination and axonal degeneration, processes that can be probed using diffusion tensor imaging (DTI). In the brain, white matter (WM) tractography en…
View article: Comparing single-shot EPI and 2D-navigated, multi-shot EPI diffusion tensor imaging acquisitions in the lumbar spinal cord at 3T
Comparing single-shot EPI and 2D-navigated, multi-shot EPI diffusion tensor imaging acquisitions in the lumbar spinal cord at 3T Open
Diffusion tensor imaging (DTI) can provide insights into spinal cord microstructure in health and disease; however, its application has been largely limited to cervical spinal segments using single-shot echo-planar imaging (EPI) diffusion-…
View article: Monitoring morphometric drift in lifelong learning segmentation of the spinal cord.
Monitoring morphometric drift in lifelong learning segmentation of the spinal cord. Open
Morphometric measures derived from spinal cord segmentations can serve as diagnostic and prognostic biomarkers in neurological diseases and injuries affecting the spinal cord. For instance, the spinal cord cross-sectional area can be used …
View article: Changes in functional connectivity in relapsing-remitting multiple sclerosis spinal cord measured via region-based and data-driven analyses
Changes in functional connectivity in relapsing-remitting multiple sclerosis spinal cord measured via region-based and data-driven analyses Open
The clinical picture of persons with multiple sclerosis (pwMS), a neuroinflammatory disease characterized by demyelination, does not consistently correlate with pathology noted on clinical magnetic resonance imaging (MRI). Functional MRI (…
View article: Body size and intracranial volume interact with the structure of the central nervous system: A multi-center in vivo neuroimaging study
Body size and intracranial volume interact with the structure of the central nervous system: A multi-center in vivo neuroimaging study Open
Clinical research emphasizes the implementation of rigorous and reproducible study designs that rely on between-group matching or controlling for sources of biological variation such as subject’s sex and age. However, corrections for body …
View article: Exploring subcortical pathology and processing speed in neuromyelitis optica spectrum disorder with myelin water imaging
Exploring subcortical pathology and processing speed in neuromyelitis optica spectrum disorder with myelin water imaging Open
Background and Purpose Neuromyelitis optica spectrum disorder (NMOSD) affects the optic nerves and spinal cord but can also cause focal brain inflammation. Subcortical pathology may contribute to the etiology of cognitive deficits in NMOSD…
View article: Biological variation in cervical spinal cord MRI morphometry in healthy individuals and people with multiple sclerosis
Biological variation in cervical spinal cord MRI morphometry in healthy individuals and people with multiple sclerosis Open
Background and Purpose Conclusions from prior literature regarding the impact of sex, age, and height on spinal cord (SC) MRI morphometrics are conflicting, while the effect of body weight on SC morphometrics has been found to be nonsignif…
View article: Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study
Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study Open
Clinical research emphasizes the implementation of rigorous and reproducible study designs that rely on between-group matching or controlling for sources of biological variation such as subject’s sex and age. However, corrections for body …
View article: Influence of preprocessing, distortion correction and cardiac triggering on the quality of diffusion MR images of spinal cord
Influence of preprocessing, distortion correction and cardiac triggering on the quality of diffusion MR images of spinal cord Open
Diffusion MRI of the spinal cord (SC) is susceptible to geometric distortion caused by field inhomogeneities, and prone to misalignment across time series and signal dropout caused by biological motion. Several modifications of image acqui…
View article: Cervical spinal cord susceptibility-weighted MRI at 7T: Application to multiple sclerosis
Cervical spinal cord susceptibility-weighted MRI at 7T: Application to multiple sclerosis Open
In this first study of SWI at 7T in the human spinal cord, SWI holds promise in advancing our understanding of disease processes in the cervical cord in MS.
View article: Detecting macromolecular differences of the CSF in low disability multiple sclerosis using quantitative MT MRI at 3T
Detecting macromolecular differences of the CSF in low disability multiple sclerosis using quantitative MT MRI at 3T Open
Background Imaging investigation of cerebrospinal fluid (CSF) in multiple sclerosis (MS) is understudied. Development of noninvasive methods to detect pathological CSF changes would have a profound effect on MS diagnosis and would offer in…
View article: Influence of preprocessing, distortion correction and cardiac triggering on the quality of diffusion MR images of spinal cord
Influence of preprocessing, distortion correction and cardiac triggering on the quality of diffusion MR images of spinal cord Open
Diffusion MRI of the spinal cord (SC) is susceptible to geometric distortion caused by field inhomogeneities, and prone to misalignment across time series and signal dropout caused by biological motion. Several modifications of image acqui…
View article: Relaxation-Compensated Chemical Exchange Saturation Transfer MRI in the Brain at 7T: Application in Relapsing-Remitting Multiple Sclerosis
Relaxation-Compensated Chemical Exchange Saturation Transfer MRI in the Brain at 7T: Application in Relapsing-Remitting Multiple Sclerosis Open
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) can probe tissue biochemistry in vivo with high resolution and sensitivity without requiring exogenous contrast agents. Applying CEST MRI at ultrahigh field prov…
View article: Patch2Self denoising of diffusion MRI in the cervical spinal cord improves intra-cord contrast, signal modelling, repeatability, and feature conspicuity
Patch2Self denoising of diffusion MRI in the cervical spinal cord improves intra-cord contrast, signal modelling, repeatability, and feature conspicuity Open
Quantitative diffusion MRI (dMRI) is a promising technique for evaluating the spinal cord in health and disease. However, low signal-to-noise ratio (SNR) can impede interpretation and quantification of these images. The purpose of this stu…
View article: Generic acquisition protocol for quantitative MRI of the spinal cord
Generic acquisition protocol for quantitative MRI of the spinal cord Open
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges, including a lack of standardized imaging protocols. Here we present a prospectively harmonized quantitative MRI protocol, which we refer to as the spi…
View article: Test–retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and<scp>A</scp>lzheimer's disease populations
Test–retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and<span>A</span>lzheimer's disease populations Open
The hippocampal formation is a complex brain structure that is important in cognitive processes such as memory, mood, reward processing and other executive functions. Histological and neuroimaging studies have implicated the hippocampal re…
View article: Cervical cord myelin water imaging shows degenerative changes over one year in multiple sclerosis but not neuromyelitis optica spectrum disorder
Cervical cord myelin water imaging shows degenerative changes over one year in multiple sclerosis but not neuromyelitis optica spectrum disorder Open
Spinal cord pathology is a feature of both neuromyelitis optica spectrum disorder (NMOSD) and relapsing-remitting multiple sclerosis (MS). While subclinical disease activity has been described in MS using quantitative magnetic resonance im…