Timothy M. E. Davis
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View article: Assessment of biomarkers associated with renal decline for prediction of incident distal sensory polyneuropathy in type 2 diabetes
Assessment of biomarkers associated with renal decline for prediction of incident distal sensory polyneuropathy in type 2 diabetes Open
The PromarkerD test accurately predicts diabetic kidney disease. We aimed to determine whether PromarkerD and/or its constituent biomarkers would also identify an increased risk of distal sensory polyneuropathy (DSPN) complicating type 2 d…
View article: DBOS Network Sensing: A Web Services Approach to Collaborative Awareness
DBOS Network Sensing: A Web Services Approach to Collaborative Awareness Open
DBOS (DataBase Operating System) is a novel capability that integrates web services, operating system functions, and database features to significantly reduce web-deployment effort while increasing resilience. Integration of high performan…
View article: The relationship between shrunken pore syndrome/selective glomerular hypofiltration syndromes and all-cause mortality in the Fremantle Diabetes Study Phase II. Reply to Gu X, Wei Y [letter]
The relationship between shrunken pore syndrome/selective glomerular hypofiltration syndromes and all-cause mortality in the Fremantle Diabetes Study Phase II. Reply to Gu X, Wei Y [letter] Open
View article: Effects of subclinical hypothyroidism on nephropathy complicating type 2 diabetes: The Fremantle Diabetes Study Phase II
Effects of subclinical hypothyroidism on nephropathy complicating type 2 diabetes: The Fremantle Diabetes Study Phase II Open
Context It is uncertain whether subclinical hypothyroidism (SCH) contributes to intrinsic renal dysfunction in people with type 2 diabetes mellitus. Objective To investigate whether SCH persisting over 4 years is associated with incident i…
View article: Exogenous Insulin Antibody Syndrome: A Rare Cause of Extreme Insulin Resistance Treated With High-dose Corticosteroids
Exogenous Insulin Antibody Syndrome: A Rare Cause of Extreme Insulin Resistance Treated With High-dose Corticosteroids Open
Exogenous insulin antibody syndrome is a rare condition characterized by extreme insulin resistance caused by antibodies that neutralize the action of insulin. An 80-year-old woman with type 1 diabetes mellitus was transferred to an Austra…
View article: Australian and New Zealand joint society consensus statement on genetic testing for monogenic diabetes in adults
Australian and New Zealand joint society consensus statement on genetic testing for monogenic diabetes in adults Open
Introduction Monogenic diabetes accounts for 2–5% of diabetes. Although its identification has substantial therapeutic implications, more than 80% of affected individuals are undiagnosed or misdiagnosed as having type 1 or 2 diabetes. This…
View article: Determinants of temporal change in telomere length and its associations with chronic complications and mortality in type 2 diabetes: the Fremantle diabetes study phase II
Determinants of temporal change in telomere length and its associations with chronic complications and mortality in type 2 diabetes: the Fremantle diabetes study phase II Open
Background Relative telomere length (rTL), a biomarker of biological ageing, has been implicated in type 2 diabetes and its complications. We aimed to identify the associates of rTL change over 4 years (∆rTL), and to investigate whether rT…
View article: The relationship between shrunken pore syndrome and all-cause mortality in people with type 2 diabetes and normal renal function: the Fremantle Diabetes Study Phase II
The relationship between shrunken pore syndrome and all-cause mortality in people with type 2 diabetes and normal renal function: the Fremantle Diabetes Study Phase II Open
View article: Clinical Features and Implications of Albuminuria Trajectories in Type 2 Diabetes: The Fremantle Diabetes Study Phase 2
Clinical Features and Implications of Albuminuria Trajectories in Type 2 Diabetes: The Fremantle Diabetes Study Phase 2 Open
Context The urinary albumin:creatinine ratio (uACR) can exhibit significant temporal changes but few studies have characterized transition patterns between uACR categories in type 2 diabetes. Objective The study aim was to use group-based …
View article: Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase <scp>II</scp>
Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase <span>II</span> Open
The prevalence of autoimmune diabetes was assessed in 113 indigenous and 1555 non‐indigenous participants in the Fremantle Diabetes Study Phase II. Both type 1 diabetes (3.5% vs. 8.2%) and latent autoimmune diabetes of adults diagnosed bas…
View article: LIFETIME MAJOR DEPRESSION AFFECTS SELF-EFFICACY AND ILLNESS PERCEPTIONS IN DIABETES BY INCREASING DEPRESSION AND DISTRESS
LIFETIME MAJOR DEPRESSION AFFECTS SELF-EFFICACY AND ILLNESS PERCEPTIONS IN DIABETES BY INCREASING DEPRESSION AND DISTRESS Open
LIFETIME MAJOR DEPRESSION AFFECTS SELF-EFFICACY AND ILLNESS PERCEPTIONS IN DIABETES BY INCREASING DEPRESSION AND DISTRESS
View article: RISK FACTORS FOR, AND COURSE OF, GENERALIZED ANXIETY SYMPTOMS IN TYPE 2 DIABETES ASSESSED FROM 6-YEAR ANXIETY TRAJECTORIES USING LATENT CURVE GROWTH ANALYSIS
RISK FACTORS FOR, AND COURSE OF, GENERALIZED ANXIETY SYMPTOMS IN TYPE 2 DIABETES ASSESSED FROM 6-YEAR ANXIETY TRAJECTORIES USING LATENT CURVE GROWTH ANALYSIS Open
RISK FACTORS FOR, AND COURSE OF, GENERALIZED ANXIETY SYMPTOMS IN TYPE 2 DIABETES ASSESSED FROM 6-YEAR ANXIETY TRAJECTORIES USING LATENT CURVE GROWTH ANALYSIS
View article: Incidence and predictors of transurethral resection of prostate in men with and without type 2 diabetes: the Fremantle Diabetes Study Phase I
Incidence and predictors of transurethral resection of prostate in men with and without type 2 diabetes: the Fremantle Diabetes Study Phase I Open
Background The relationship between type 2 diabetes and the incidence of transurethral resection of the prostate (TURP) remains uncertain. Aims To utilise data from the Fremantle Diabetes Study Phase I (FDS1) to examine the association bet…
View article: PromarkerD Versus Standard of Care Biochemical Measures for Assessing Future Renal Function Decline in Type 2 Diabetes
PromarkerD Versus Standard of Care Biochemical Measures for Assessing Future Renal Function Decline in Type 2 Diabetes Open
Background/Objectives: The current standard of care for assessing chronic kidney disease complicating diabetes (DKD) includes measurement of estimated glomerular filtration rate (eGFR) and urinary albumin:creatinine ratio (uACR) but both t…
View article: A simplified amoxicillin regimen with dose frequency based on post-natal age in neonates with confirmed or suspected infection
A simplified amoxicillin regimen with dose frequency based on post-natal age in neonates with confirmed or suspected infection Open
Amoxicillin plus gentamicin is the recommended first-line empiric therapy for neonates with infection. Guidelines vary widely in dose (mg/kg), dose frequency, and adjustments according to post-menstrual age (PMA) and post-natal age (PNA). …
View article: Cardiovascular Risk and Plasma N-terminal Pro-B-type Natriuretic Peptide in Adults With Resistance to Thyroid Hormone β
Cardiovascular Risk and Plasma N-terminal Pro-B-type Natriuretic Peptide in Adults With Resistance to Thyroid Hormone β Open
Purpose People with resistance to thyroid hormone due to defective thyroid receptor β (RTHβ) exhibit adverse cardiovascular outcomes and premature mortality. Whether this reflects increased global cardiovascular disease (CVD) risk or hyper…
View article: Can Deep Learning Models Acquire Specialist Knowledge? Identifying Carotid Bruits in Type 2 Diabetes Using an Electronic Stethoscope
Can Deep Learning Models Acquire Specialist Knowledge? Identifying Carotid Bruits in Type 2 Diabetes Using an Electronic Stethoscope Open
The present study explores the potential of artificial intelligence as a substitute for trained clinician identification of a carotid bruit from multiple auditory recordings from an electronic stethoscope in 98 people with type 2 diabetes,…
View article: Severe Hypomagnesemia and Hypocalcemia Linked to Semaglutide in Type 2 Diabetes: A Case Report
Severe Hypomagnesemia and Hypocalcemia Linked to Semaglutide in Type 2 Diabetes: A Case Report Open
BACKGROUND Although hypomagnesemia is common in type 2 diabetes, clinical presentations with severe hypomagnesemia are rare. A number of oral blood glucose-lowering medications can reduce serum magnesium concentrations, and several severe …
View article: Interface for Sparse Linear Algebra Operations
Interface for Sparse Linear Algebra Operations Open
The standardization of an interface for dense linear algebra operations in the BLAS standard has enabled interoperability between different linear algebra libraries, thereby boosting the success of scientific computing, in particular in sc…
View article: Traceback and Testing of Food Epidemiologically Linked to a Norovirus Outbreak at a Wedding Reception
Traceback and Testing of Food Epidemiologically Linked to a Norovirus Outbreak at a Wedding Reception Open
View article: The relationship between serum HDL-cholesterol, cardiovascular disease and mortality in community-based people with type 2 diabetes: the Fremantle Diabetes Study phase 2
The relationship between serum HDL-cholesterol, cardiovascular disease and mortality in community-based people with type 2 diabetes: the Fremantle Diabetes Study phase 2 Open
Background Older general population-based studies found an inverse association between serum HDL-cholesterol and both cardiovascular disease (CVD) events and mortality, but more recent data have suggested a U-shaped relationship. Whether t…
View article: Artemisinin combination therapy at delivery to prevent postpartum malaria: A randomised open-label controlled trial
Artemisinin combination therapy at delivery to prevent postpartum malaria: A randomised open-label controlled trial Open
A treatment course of ACT at time of delivery halved the incidence of malaria infection during the first 6-month postpartum.
View article: Application of a validated prognostic plasma protein biomarker test for renal decline in type 2 diabetes to type 1 diabetes: the Fremantle Diabetes Study Phase II
Application of a validated prognostic plasma protein biomarker test for renal decline in type 2 diabetes to type 1 diabetes: the Fremantle Diabetes Study Phase II Open
View article: Anonymized Network Sensing Graph Challenge
Anonymized Network Sensing Graph Challenge Open
The MIT/IEEE/Amazon GraphChallenge encourages community approaches to developing new solutions for analyzing graphs and sparse data derived from social media, sensor feeds, and scientific data to discover relationships between events as th…
View article: The inter-relationship between Helicobacter pylori infection, dementia and mortality in type 2 diabetes: The Fremantle Diabetes Study Phase I
The inter-relationship between Helicobacter pylori infection, dementia and mortality in type 2 diabetes: The Fremantle Diabetes Study Phase I Open
Although CagA seropositivity in T2DM may have a contributory etiologic role in the risk of dementia, this may be through its association with reduced cardiovascular/all-cause mortality.
View article: What is Normal? A Big Data Observational Science Model of Anonymized Internet Traffic
What is Normal? A Big Data Observational Science Model of Anonymized Internet Traffic Open
Understanding what is normal is a key aspect of protecting a domain. Other domains invest heavily in observational science to develop models of normal behavior to better detect anomalies. Recent advances in high performance graph libraries…
View article: Effect of prior gestational diabetes on the risk of cardiovascular disease and death in women with type 2 diabetes: The Fremantle Diabetes Study Phase II
Effect of prior gestational diabetes on the risk of cardiovascular disease and death in women with type 2 diabetes: The Fremantle Diabetes Study Phase II Open
Prior GDM does not increase CVD risk or all-cause mortality in women with type 2 diabetes.
View article: Validation and Application of a Dried Blood Spot Amoxicillin Assay
Validation and Application of a Dried Blood Spot Amoxicillin Assay Open
View article: Prevalence and prognostic significance of cardiac autonomic neuropathy in community-based people with type 2 diabetes: the Fremantle Diabetes Study Phase II
Prevalence and prognostic significance of cardiac autonomic neuropathy in community-based people with type 2 diabetes: the Fremantle Diabetes Study Phase II Open
Background There is a paucity of contemporary data on the prevalence and prognostic significance of cardiac autonomic neuropathy (CAN) from community-based cohorts with type 2 diabetes assessed using gold standard methods. The aim of this …
View article: Does acute malnutrition in young children increase the risk of treatment failure following artemisinin-based combination therapy? A WWARN individual patient data meta-analysis
Does acute malnutrition in young children increase the risk of treatment failure following artemisinin-based combination therapy? A WWARN individual patient data meta-analysis Open