Evelien Dekker
YOU?
Author Swipe
View article: Risk factors for dysplastic lesions in the proximal stomach in patients with familial adenomatous polyposis
Risk factors for dysplastic lesions in the proximal stomach in patients with familial adenomatous polyposis Open
Gastric cancer is a recently recognized challenge in management of familial adenomatous polyposis (FAP), mostly developing in the proximal stomach amid carpeting fundic gland polyposis. Dysplastic lesions in the proximal stomach might be t…
View article: Risk of deficient mismatch repair colorectal cancer and precursors after kidney transplantation: A nationwide study
Risk of deficient mismatch repair colorectal cancer and precursors after kidney transplantation: A nationwide study Open
Colorectal cancer (CRC) incidence rises posttransplant, though the mechanism remains unclear. We hypothesize that impaired immunosurveillance of kidney transplant recipients (KTRs) allows progression along the serrated pathway, increasing …
View article: Malignancies of the small intestine: incidence and trends in a nationwide registry
Malignancies of the small intestine: incidence and trends in a nationwide registry Open
The incidence of malignancies of the small intestine in the Netherlands has more than doubled over the past two decades, mostly due to an increase in NENs and adenocarcinomas. Survival outcomes for these malignancies did not improve, highl…
View article: Delayed post-polypectomy bleeding following cold snare polypectomy of lesions <10 mm in patients on high-dose antithrombotic therapy: insights from a Dutch colonoscopy cohort
Delayed post-polypectomy bleeding following cold snare polypectomy of lesions <10 mm in patients on high-dose antithrombotic therapy: insights from a Dutch colonoscopy cohort Open
Current guidelines state that low-risk polypectomies (cold snare polypectomies of lesions <10 mm) can be safely performed with continuation of single antiplatelet therapy (low-dose antithrombotic therapy [ATT]). The safety of low-risk poly…
View article: The diagnostic potential of urinary volatile organic compounds for colorectal neoplasia in Lynch syndrome—A prospective longitudinal study
The diagnostic potential of urinary volatile organic compounds for colorectal neoplasia in Lynch syndrome—A prospective longitudinal study Open
Post‐colonoscopy colorectal cancer (CRC) rates and colonoscopy burden are considerable in Lynch syndrome. Urinary volatile organic compounds (VOCs) have shown promise as a patient‐friendly alternative to faecal biomarkers for colorectal ne…
View article: Risk of colorectal cancer and participation in fecal immunochemical test-based screening
Risk of colorectal cancer and participation in fecal immunochemical test-based screening Open
CRC risk varies significantly between low-participation groups in the Dutch CRC screening program. Interventions should prioritize the most vulnerable groups, considering both participation and risk of CRC.
View article: Development and provider assessment of a new oncology network with care pathways for gastrointestinal cancer patients: the collaborative approach
Development and provider assessment of a new oncology network with care pathways for gastrointestinal cancer patients: the collaborative approach Open
The multicenter development and maintenance of regional care pathways for patients with gastrointestinal cancers within a regional oncology network seems feasible and effective with high satisfaction among participating hospitals. Implemen…
View article: “The world is really not built for everyone”: A qualitative investigation of suicide risk among autistic transgender and gender diverse adults and the essential role of health care providers
“The world is really not built for everyone”: A qualitative investigation of suicide risk among autistic transgender and gender diverse adults and the essential role of health care providers Open
Objective: This qualitative study aims to describe themes related to suicide risk among autistic transgender and gender diverse adults and to identify potential intervention approaches to reduce suicide risk among autistic TGD adults, with…
View article: Feasibility of amino acid profiling in long-term stored formalin-fixed paraffin-embedded colorectal neoplasia tissue
Feasibility of amino acid profiling in long-term stored formalin-fixed paraffin-embedded colorectal neoplasia tissue Open
View article: Rethinking Post-colonoscopy Colorectal Cancer Risk: Endoscopist Performance Versus Presence of High-risk Polyps
Rethinking Post-colonoscopy Colorectal Cancer Risk: Endoscopist Performance Versus Presence of High-risk Polyps Open
An individual's PCCRC risk in the initial years is primarily influenced by endoscopist performance, rather than the presence of high-risk polyps. To reduce PCCRCs, besides ensuring appropriate surveillance intervals, it is crucial to monit…
View article: Computed Tomography Colonography in Fecal Immunochemical Test Positives in a Colorectal Cancer Screening Program
Computed Tomography Colonography in Fecal Immunochemical Test Positives in a Colorectal Cancer Screening Program Open
View article: The clinicopathological features of breast cancer in Peutz-Jeghers syndrome: results from an international survey
The clinicopathological features of breast cancer in Peutz-Jeghers syndrome: results from an international survey Open
View article: Mental Health in Familial Adenomatous Polyposis: A Systematic Review
Mental Health in Familial Adenomatous Polyposis: A Systematic Review Open
Objective Familial adenomatous polyposis (FAP) is a hereditary disposition causing a nearly 100% risk of developing colorectal cancer without treatment. Therefore lifelong endoscopic surveillance and prophylactic colectomy, generally befor…
View article: Developing a New Stool Test for Colorectal Cancer Screening, the multitargetFIT (mtFIT)
Developing a New Stool Test for Colorectal Cancer Screening, the multitargetFIT (mtFIT) Open
View article: Diagnostic Accuracy of an Add‐On, Blood‐Based Screening Test for Colorectal Cancer in Two Established Screening Programmes
Diagnostic Accuracy of an Add‐On, Blood‐Based Screening Test for Colorectal Cancer in Two Established Screening Programmes Open
Background CELTiC is a blood‐based test consisting of a panel of four mRNAs ( CEACAM6 , LGALS4 , TSPAN8 and COL1A2 ) associated with colorectal cancer (CRC). CELTiC has a high sensitivity (90%) for detecting advanced neoplasia (AN) when co…
View article: Quality assurance in colonoscopy – how to interpret and implement various quality indicators related to neoplasia detection rates?
Quality assurance in colonoscopy – how to interpret and implement various quality indicators related to neoplasia detection rates? Open
View article: The impact of extended invitation intervals on stage distribution of screen‐detected and interval cancer within the Dutch colorectal cancer screening program
The impact of extended invitation intervals on stage distribution of screen‐detected and interval cancer within the Dutch colorectal cancer screening program Open
This study investigates the impact of extended invitation intervals on the stage distribution of screen‐detected and interval colorectal cancers (CRCs) in the Netherlands' fecal immunochemical test (FIT)‐based screening program during the …
View article: Developing a Strategy for Prevention of Avoidable Postcolonoscopy Colorectal Cancers: Current and Future Perspectives
Developing a Strategy for Prevention of Avoidable Postcolonoscopy Colorectal Cancers: Current and Future Perspectives Open
View article: Correction to: Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population‑Based Screening Programs
Correction to: Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population‑Based Screening Programs Open
View article: Real-time use of a virtual scale during endoscopy: a game-changer in the field of polyp size measurement?
Real-time use of a virtual scale during endoscopy: a game-changer in the field of polyp size measurement? Open
View article: Predisposing conditions in patients with small intestinal adenocarcinomas in the Netherlands: A 20‐year nationwide cohort study
Predisposing conditions in patients with small intestinal adenocarcinomas in the Netherlands: A 20‐year nationwide cohort study Open
Small intestinal adenocarcinomas (SIAs) are associated with predisposing conditions, including inflammatory bowel disease (IBD) and celiac disease, but also genetic syndromes such as Lynch syndrome (LS) and familial adenomatous polyposis (…
View article: Risk of lymph node metastasis in pT2 rectal cancer: a nationwide retrospective analysis
Risk of lymph node metastasis in pT2 rectal cancer: a nationwide retrospective analysis Open
View article: Impact of standard enhancement settings of endoscopy systems on performance of endoscopic artificial intelligence systems
Impact of standard enhancement settings of endoscopy systems on performance of endoscopic artificial intelligence systems Open
Background Artificial intelligence (AI) systems in endoscopy are predominantly developed and tested using high-quality imagery from expert centers. However, their performance may be different when applied in clinical practice, partly due t…
View article: Clinician-reported Gloucester Comfort Scale scores underestimate patient discomfort and pain during colonoscopy: insights from comparison with a patient-reported experience measure
Clinician-reported Gloucester Comfort Scale scores underestimate patient discomfort and pain during colonoscopy: insights from comparison with a patient-reported experience measure Open
Patient experience is a fundamental element of colonoscopy. The Gloucester Comfort Scale (GCS) is used by clinicians to report patient comfort. However, insights regarding the extent to which clinician-reported GCS scores represent the pat…
View article: Cell type-specific eQTL detection from single-cell RNA-seq reveals post-transcriptional regulatory mechanisms in human islets
Cell type-specific eQTL detection from single-cell RNA-seq reveals post-transcriptional regulatory mechanisms in human islets Open
Gene regulatory networks (GRN) must be robust to maintain cellular identity across individuals yet flexible to accommodate population genetic variants. Therefore, comparing expression quantitative trait loci (eQTL) in health and disease ca…
View article: The challenge of preventing gastric cancer in patients under surveillance for familial adenomatous polyposis
The challenge of preventing gastric cancer in patients under surveillance for familial adenomatous polyposis Open
Several extra-colonic manifestations, including duodenal polyposis and desmoid tumors, are well-described manifestations in familial adenomatous polyposis (FAP). More recently, an increase in gastric cancer diagnoses has been observed in F…
View article: Tough Men, Healthy Guts: A Cross-Sectional Survey on the Role of Masculinity in the Curaçao Colorectal Cancer (Crc) Screening Program
Tough Men, Healthy Guts: A Cross-Sectional Survey on the Role of Masculinity in the Curaçao Colorectal Cancer (Crc) Screening Program Open
View article: Interval cancer risk after the upper age limit of screening has been reached: Informing risk stratification in <scp>FIT</scp>‐based colorectal cancer screening
Interval cancer risk after the upper age limit of screening has been reached: Informing risk stratification in <span>FIT</span>‐based colorectal cancer screening Open
Upper age limits are currently fixed for all fecal immunochemical test (FIT)‐based colorectal cancer (CRC) screening programs. A risk‐stratified upper age limit may be beneficial. Therefore, we assessed differences in interval CRC risk amo…
View article: Detecting Colorectal Neoplasia Using Specific Fecal Fluorogenic Protease-Sensitive Substrates: A Pilot Study
Detecting Colorectal Neoplasia Using Specific Fecal Fluorogenic Protease-Sensitive Substrates: A Pilot Study Open
we successfully developed colorectal neoplasia-specific fluorogenic substrates, highlighting the ED substrate as a potential substrate for the detection of AA and CRC. Although the responsible proteases require further identification, our …
View article: Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population-Based Screening Programs
Fecal Immunochemical Test Positivity Thresholds: An International Survey of Population-Based Screening Programs Open
This international survey has documented the wide range of FIT positivity thresholds that are in current use. Quantitative FITs enable programs to achieve the desired program outcomes within available resource constraints by adjusting the …