Elisabeth G. Vichaya
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View article: Author response: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Author response: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
View article: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a mouse model for head and neck cancer and neur…
View article: Author response: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Author response: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a mouse model for head and neck cancer and neur…
View article: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a mouse model for head and neck cancer and neur…
View article: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a male mouse model for head and neck cancer, we…
View article: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a mouse model for head and neck cancer and neur…
View article: Reviewer #1 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Reviewer #1 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a male mouse model for head and neck cancer, we…
View article: Reviewer #3 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Reviewer #3 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a male mouse model for head and neck cancer, we…
View article: Reviewer #2 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Reviewer #2 (Public Review): Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a male mouse model for head and neck cancer, we…
View article: Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer Open
Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a mouse model for head and neck cancer and neur…
View article: Figure S1 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S1 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains additional inflammatory phenotyping of the mEER tumor, including serum cytokine levels and brain region-specific cytokine expression profiles.
View article: Figure S3 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S3 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains correlations between wheel running and each of tumor volume and plasma IL-6 levels. Also, inflammasome and IL-1 response genes in the brain and liver are presented here.
View article: Figure S1 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S1 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains additional inflammatory phenotyping of the mEER tumor, including serum cytokine levels and brain region-specific cytokine expression profiles.
View article: Supplementary Materials from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Supplementary Materials from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains methods and references for data presented in the supplement and legends for Supplementary Figures S1-S4
View article: Data from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Data from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
Fatigue is the most common symptom of cancer at diagnosis, yet causes and effective treatments remain elusive. As tumors can be highly inflammatory, it is generally accepted that inflammation mediates cancer-related fatigue. However, evide…
View article: Figure S4 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S4 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file shows burrowing behavior in tumor-bearing mice that were or were not treated with systemic IL-1ra.
View article: Figure S3 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S3 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains correlations between wheel running and each of tumor volume and plasma IL-6 levels. Also, inflammasome and IL-1 response genes in the brain and liver are presented here.
View article: Data from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Data from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
Fatigue is the most common symptom of cancer at diagnosis, yet causes and effective treatments remain elusive. As tumors can be highly inflammatory, it is generally accepted that inflammation mediates cancer-related fatigue. However, evide…
View article: Figure S4 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S4 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file shows burrowing behavior in tumor-bearing mice that were or were not treated with systemic IL-1ra.
View article: Figure S2 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S2 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains additional behavioral data related to the progressive ratio task following both LPS and tumor-challenge as well as additional behavioral phenotyping of tumor-bearing mice.
View article: Figure S2 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Figure S2 from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains additional behavioral data related to the progressive ratio task following both LPS and tumor-challenge as well as additional behavioral phenotyping of tumor-bearing mice.
View article: Supplementary Materials from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling
Supplementary Materials from Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling Open
This file contains methods and references for data presented in the supplement and legends for Supplementary Figures S1-S4
View article: Chronic Stress Exacerbates Hyperglycemia-Induced Affective Symptoms in Male Mice
Chronic Stress Exacerbates Hyperglycemia-Induced Affective Symptoms in Male Mice Open
Introduction: Among chronically ill populations, affective disorders remain underdiagnosed and undertreated. A high degree of comorbidity exists between diabetes and affective disorders, particularly depression and anxiety. T…
View article: Associative learning contributes to the persistence of fatigue-like behavior in male mice in a model of cancer survivorship
Associative learning contributes to the persistence of fatigue-like behavior in male mice in a model of cancer survivorship Open
View article: Sex differences in the behavioral and immune responses of mice to tumor growth and cancer therapy
Sex differences in the behavioral and immune responses of mice to tumor growth and cancer therapy Open
View article: Social isolation induces hyperactivity and exploration in aged female mice
Social isolation induces hyperactivity and exploration in aged female mice Open
Prolonged social isolation is associated with poor physical and mental health outcomes, findings observed in both humans, and rodent models of isolation. Humans, like mice, may engage in enhanced exploratory and social behaviour following …
View article: Lipopolysaccharide does not alter behavioral response to successive negative contrast in mice
Lipopolysaccharide does not alter behavioral response to successive negative contrast in mice Open
View article: Toll-like receptor 4 mediates the development of fatigue in the murine Lewis Lung Carcinoma model independently of activation of macrophages and microglia
Toll-like receptor 4 mediates the development of fatigue in the murine Lewis Lung Carcinoma model independently of activation of macrophages and microglia Open
View article: Pilot study of neurologic toxicity in mice after proton minibeam therapy
Pilot study of neurologic toxicity in mice after proton minibeam therapy Open
Proton minibeams (MBs) comprised of parallel planar beamlets were evaluated for their ability to spare healthy brain compared to proton broad beams (BBs). Juvenile mice were given partial brain irradiation of 10 or 30 Gy integral dose usin…
View article: Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats
Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats Open
Background Production of inflammatory mediators by reactive microglial cells in the brain is generally considered the primary mechanism underlying the development of symptoms of sickness in response to systemic inflammation. Methods Deplet…