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View article: Chronic Abdominal Pain After Roux-en-Y Gastric Bypass Surgery: A Prospective Cohort Study with 2-Year Follow-Up in a Swedish Population
Chronic Abdominal Pain After Roux-en-Y Gastric Bypass Surgery: A Prospective Cohort Study with 2-Year Follow-Up in a Swedish Population Open
Background The risk of developing chronic abdominal pain after Roux-en-Y gastric bypass (RYGB) surgery has come under scrutiny. Few prospective studies exist on this subject. The aim of this prospective paired analysis cohort study was to …
View article: Perception of cure and quality of life in anal cancer survivors
Perception of cure and quality of life in anal cancer survivors Open
Background and purpose: Anal cancer is treated with chemoradiotherapy and with salvage surgery in case of local failure. Curation rate depends on tumour stage but is overall high (80–90%). This study explored anal cancer survivors’ percept…
View article: Short‐term morbidity and mortality following surgical treatment of anal squamous cell carcinoma in Sweden – A national multicentre study
Short‐term morbidity and mortality following surgical treatment of anal squamous cell carcinoma in Sweden – A national multicentre study Open
Introduction Anal squamous cell carcinoma (ASCC) is primarily treated with chemoradiotherapy (CRT), but surgery can be curative following treatment failure. The treatment of ASCC was centralised in Sweden in 2017. This study aims to descri…
View article: Adverse events during radical prostatectomy and their association with recurrence and death
Adverse events during radical prostatectomy and their association with recurrence and death Open
View article: Reply to Natália Dalsenter Avilez, Tomás Bernardo Costa Moretti, and Leonardo Oliveira Reis’ Letter to the Editor re: Anna Lantz, Ying Li, Stefan Carlsson, et al. Robotic Versus Open Radical Prostatectomy, Differences in Prostate Cancer-specific Survival—12 Years of Follow-up in the LAParoscopic Prostatectomy Robot Open Trial. Eur Urol Oncol. In press. https://doi.org/10.1016/j.euo.2025.05.004
Reply to Natália Dalsenter Avilez, Tomás Bernardo Costa Moretti, and Leonardo Oliveira Reis’ Letter to the Editor re: Anna Lantz, Ying Li, Stefan Carlsson, et al. Robotic Versus Open Radical Prostatectomy, Differences in Prostate Cancer-specific Survival—12 Years of Follow-up in the LAParoscopic Prostatectomy Robot Open Trial. Eur Urol Oncol. In press. https://doi.org/10.1016/j.euo.2025.05.004 Open
View article: Postoperative complications in Hartmann’s procedure <i>versus</i> intersphincteric abdominoperineal excision in rectal cancer: randomized clinical trial (HAPIrect)
Postoperative complications in Hartmann’s procedure <i>versus</i> intersphincteric abdominoperineal excision in rectal cancer: randomized clinical trial (HAPIrect) Open
Background In patients with rectal cancer, when it is not possible to restore bowel continuity with an anastomosis, the optimal surgical method is still a matter of debate. The aim of this trial was to determine 30-day postoperative surgic…
View article: Cross-cultural adaptation of the locally recurrent rectal cancer – Quality of life questionnaire
Cross-cultural adaptation of the locally recurrent rectal cancer – Quality of life questionnaire Open
The LRRC-QoL has now undergone cross-cultural adaptation to enable its use in 10 languages and 16 countries. Its psychometric properties will be further examined through external validation in an international cohort.
View article: Extended Mesenteric Resection in Crohn's Disease: EXCEED Study Protocol - a blinded multicenter randomized controlled clinical trial (RCT)
Extended Mesenteric Resection in Crohn's Disease: EXCEED Study Protocol - a blinded multicenter randomized controlled clinical trial (RCT) Open
Background Crohn's disease presents a persistent challenge, particularly concerning disease recurrence in patients after previous intestinal resection. This recurrence often necessitates additional medical treatment or surgery, imposing a …
View article: Adverse Events During Radical Prostatectomy and Their Association With Reccurence and Death
Adverse Events During Radical Prostatectomy and Their Association With Reccurence and Death Open
Objective The objective was to explore if adverse events during radical prostatectomy for prostate cancer were associated with the oncological outcomes recurrence, all-cause and prostate cancer specific mortality. One further was to identi…
View article: Frailty Is an Independent Marker of Post‐Operative Mortality Following Colorectal Cancer Resection Surgery in Older Adults
Frailty Is an Independent Marker of Post‐Operative Mortality Following Colorectal Cancer Resection Surgery in Older Adults Open
Background and Objectives Frailty is a prognostic factor of post‐operative death and complications following colorectal cancer surgery. Frailty assessment is not routinely performed, hence, the prevalence is unknown. The aim of this study …
View article: Robotic Versus Open Radical Prostatectomy, Differences in Prostate Cancer–specific Survival—12 Years of Follow-up in the LAParoscopic Prostatectomy Robot Open Trial
Robotic Versus Open Radical Prostatectomy, Differences in Prostate Cancer–specific Survival—12 Years of Follow-up in the LAParoscopic Prostatectomy Robot Open Trial Open
At 12 yr after surgery, prostate cancer-specific mortality was significantly lower in patients undergoing robotic prostatectomy than in those undergoing open prostatectomy. Cautious interpretation is suggested for the possible causal effec…
View article: Rectus abdominis muscle atrophy, prophylactic mesh, and stoma placement: retrospective findings from a prospective multicenter trial
Rectus abdominis muscle atrophy, prophylactic mesh, and stoma placement: retrospective findings from a prospective multicenter trial Open
View article: Laparoscopic lavage in a purulent peritonitis model: impact on inflammatory proteins
Laparoscopic lavage in a purulent peritonitis model: impact on inflammatory proteins Open
View article: Persistent Sitting and Walking Difficulties After Abdominoperineal Excision and Anterior Resection: Results From the Quality of Life in Rectal Cancer Study
Persistent Sitting and Walking Difficulties After Abdominoperineal Excision and Anterior Resection: Results From the Quality of Life in Rectal Cancer Study Open
BACKGROUND: The main surgical resection options in rectal cancer are anterior resection for tumors in the mid- or upper rectum and abdominoperineal excision for tumors in the lower rectum. A previous study showed long-term persistent perin…
View article: Survivorship issues in long‐term survivors of locally recurrent rectal cancer: A qualitative study
Survivorship issues in long‐term survivors of locally recurrent rectal cancer: A qualitative study Open
Aim There are increasing numbers of long‐term survivors following curative treatment for locally recurrent rectal cancer (LRRC); however, their experiences remain relatively underreported. The aim of this qualitative study was to identify …
View article: Short-term outcomes from the ‘Watch and Wait’ (WoW) study: prospective cohort study
Short-term outcomes from the ‘Watch and Wait’ (WoW) study: prospective cohort study Open
Background Despite absence of level 1 evidence on the long-term oncological safety of non-operative management for rectal cancer (watch and wait), increased implementation has occurred globally over the past decades. In Sweden, a pan-natio…
View article: Assessment of cognitive function after surgery for colorectal cancer—a scoping review
Assessment of cognitive function after surgery for colorectal cancer—a scoping review Open
Objective Colorectal cancer is primarily treated with surgery. Major surgery and older age are risk factors associated with postoperative decline in cognitive function. In clinical research, a wide range of instruments have been used to as…
View article: International consensus to define outcomes for trials of chemoradiotherapy for anal cancer (CORMAC-2): defining the outcomes from the CORMAC core outcome set
International consensus to define outcomes for trials of chemoradiotherapy for anal cancer (CORMAC-2): defining the outcomes from the CORMAC core outcome set Open
Variation in outcomes definitions and reporting limit the utility of clinical trial results. The Core Outcome Research Measures in Anal Cancer (CORMAC) project developed a core outcome set (COS) for chemoradiotherapy trials for anal squamo…
View article: Patient reported experiences of health care, quality of life and preoperative information in colon cancer
Patient reported experiences of health care, quality of life and preoperative information in colon cancer Open
Background and purpose: Cancer may create problems and needs associated with impaired quality of life (QoL). The first health care encounter is important to enable patients to cope and may ultimately impact QoL. The aim of this study was t…
View article: Total neoadjuvant treatment using short-course radiotherapy and four CAPOX cycles in locally advanced rectal cancer with high-risk criteria for recurrence: a Swedish nationwide cohort study (LARCT-US)
Total neoadjuvant treatment using short-course radiotherapy and four CAPOX cycles in locally advanced rectal cancer with high-risk criteria for recurrence: a Swedish nationwide cohort study (LARCT-US) Open
View article: 72298 - High mortality after surgery for perforated diverticulitis Hinchey grade IV was mediated by sepsis
72298 - High mortality after surgery for perforated diverticulitis Hinchey grade IV was mediated by sepsis Open
Introduction Studies of perforated diverticulitis have mainly been focused on choice of surgical method and few have included faecal peritonitis, Hinchey grade IV. The aim was to study a national cohort of patients operated for Hinchey IV …
View article: 72321 - Validation of the reporting of local recurrence of rectal cancer in the Swedish ColoRectal Cancer Registry (SCRCR)
72321 - Validation of the reporting of local recurrence of rectal cancer in the Swedish ColoRectal Cancer Registry (SCRCR) Open
Introduction The Swedish ColoRectal Cancer Registry (SCRCR) includes data on patients with rectal cancer in Sweden with a coverage rate of 98.5%. While variables on primary diagnosis and treatment have been shown to have good validity, loc…
View article: 71953 - Persistent sitting and walking difficulties after abdominoperineal excision - results from the QoLiRECT study
71953 - Persistent sitting and walking difficulties after abdominoperineal excision - results from the QoLiRECT study Open
Introduction The surgical resection options in rectal cancer are anterior resection for tumours in the mid or upper rectum and abdominoperineal excision for tumours in the lower rectum. One previous study has shown long-term persistent per…
View article: 72238 - Major LARS in patients with rectal cancer following a Watch and Wait protocol – results from the Swedish national Wow study
72238 - Major LARS in patients with rectal cancer following a Watch and Wait protocol – results from the Swedish national Wow study Open
Introduction Rectal cancer has historically been treated with resection surgery. (Chemo)radiotherapy results in a clinical complete response (cCR) in some patients, which enables a nonoperative management; “watch and wait”. Low Anterior Re…
View article: 71670 - Survival and oncological outcomes in colorectal cancer patients undergoing urological resections: A National Study Cohort
71670 - Survival and oncological outcomes in colorectal cancer patients undergoing urological resections: A National Study Cohort Open
Introduction Colorectal cancer (CRC) growing into urinary organs may require en-bloc resections such as total cystectomy (TC), partial cystectomy (PC), or ureter resection (UR). This study aimed to investigate survival and oncological outc…
View article: 71973 - Short-term morbidity and mortality following surgical treatment of anal squamous cell carcinoma in Sweden – a national multicenter study
71973 - Short-term morbidity and mortality following surgical treatment of anal squamous cell carcinoma in Sweden – a national multicenter study Open
Introduction Anal squamous cell carcinoma (ASCC) is primarily treated with chemoradiotherapy (CRT). Salvage surgery is a potentially curative treatment following CRT failure. Centralization of surgery was implemented in 2017 to improve ASC…
View article: Bowel Dysfunction After Colon Cancer Surgery: A Prospective, Longitudinal, Multicenter Study
Bowel Dysfunction After Colon Cancer Surgery: A Prospective, Longitudinal, Multicenter Study Open
BACKGROUND: Longitudinal studies on functional outcomes after colon resection are limited. OBJECTIVE: To evaluate bowel dysfunction and related distress 1 and 3 years after colon resection using the low anterior resection syndrome score as…
View article: Suicide after colorectal cancer—a national population‐based study
Suicide after colorectal cancer—a national population‐based study Open
Aim A cancer diagnosis is often associated with physical as well as emotional distress. Previous studies indicate a higher risk for suicide in patients diagnosed with cancer. The aim of this study was to investigate the prevalence of death…
View article: Patient reported long‐term side effects from treatment on urinary and sexual function in anal cancer survivors – 3‐ and 6‐year results from the Swedish national <scp>ANCA</scp> study
Patient reported long‐term side effects from treatment on urinary and sexual function in anal cancer survivors – 3‐ and 6‐year results from the Swedish national <span>ANCA</span> study Open
Aim The standard treatment for anal cancer is chemoradiotherapy. Most patients survive anal cancer but remain living with long‐term side effects related to the treatment received. The aim of this study was to assess the occurrence of long‐…
View article: Patients’ and carers’ views on research priorities in prehabilitation for cancer surgery
Patients’ and carers’ views on research priorities in prehabilitation for cancer surgery Open