E. I. Volkova
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View article: Transcription factor DREF regulates expression of the microRNA gene <i>bantam in Drosophila melanogaster</i>
Transcription factor DREF regulates expression of the microRNA gene <i>bantam in Drosophila melanogaster</i> Open
The bantam gene encodes a vital microRNA and has a complex expression pattern in various tissues at different stages of Drosophila development. This microRNA is involved in the control of normal development of the ocu lar and wing imaginal…
View article: New Mutations in the 5′ Region of the Notch Gene Affect Drosophila melanogaster Oogenesis
New Mutations in the 5′ Region of the Notch Gene Affect Drosophila melanogaster Oogenesis Open
The Notch pathway is an important and evolutionarily conserved signaling system involved in the development of multicellular organisms. Notch signaling plays an important role in the regulation of proliferation and differentiation of many …
View article: Structural and Functional Dissection of the 5′ Region of the Notch Gene in Drosophila melanogaster
Structural and Functional Dissection of the 5′ Region of the Notch Gene in Drosophila melanogaster Open
Notch is a key factor of a signaling cascade which regulates cell differentiation in all multicellular organisms. Numerous investigations have been directed mainly at studying the mechanism of Notch protein action; however, very little is …
View article: The study of the regulatory region of the Drosophila melanogaster Notch gene by new methods of directed genome editing
The study of the regulatory region of the Drosophila melanogaster Notch gene by new methods of directed genome editing Open
The Notch gene plays a key role in the development of organs and tissues of neuroectodermic origin, including the nervous system. In eukaryotic organisms, the Notch pathway is involved in cell fate determination. The Notch gene was first d…
View article: Tethering of CHROMATOR and dCTCF proteins results in decompaction of condensed bands in the Drosophila melanogaster polytene chromosomes but does not affect their transcription and replication timing
Tethering of CHROMATOR and dCTCF proteins results in decompaction of condensed bands in the Drosophila melanogaster polytene chromosomes but does not affect their transcription and replication timing Open
Instulator proteins are central to domain organization and gene regulation in the genome. We used ectopic tethering of CHROMATOR (CHRIZ/CHRO) and dCTCF to pre-defined regions of the genome to dissect the influence of these proteins on loca…