Matthew Monroe
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View article: Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer Open
View article: Integrative Multi-PTM Proteomics Reveals Dynamic Global, Redox, Phosphorylation, and Acetylation Regulation in Cytokine-Treated Pancreatic Beta Cells
Integrative Multi-PTM Proteomics Reveals Dynamic Global, Redox, Phosphorylation, and Acetylation Regulation in Cytokine-Treated Pancreatic Beta Cells Open
View article: Advanced multi-modal mass spectrometry imaging reveals functional differences of placental villous compartments at microscale resolution
Advanced multi-modal mass spectrometry imaging reveals functional differences of placental villous compartments at microscale resolution Open
View article: Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions
Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions Open
Alzheimer's disease (AD) is a neurodegenerative disease with a complex etiology influenced by confounding factors such as genetic polymorphisms, age, sex, and race. Traditionally, AD research has not prioritized these influences, resulting…
View article: Integrative Multi-PTM Proteomics Reveals Dynamic Global, Redox, Phosphorylation, and Acetylation Regulation in Cytokine-Treated Pancreatic Beta Cells
Integrative Multi-PTM Proteomics Reveals Dynamic Global, Redox, Phosphorylation, and Acetylation Regulation in Cytokine-Treated Pancreatic Beta Cells Open
Studying regulation of protein function at a systems level necessitates an understanding of the interplay among diverse posttranslational modifications (PTMs). A variety of proteomics sample processing workflows are currently used to study…
View article: Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications
Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications Open
Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications
View article: Changes in maternal blood and placental lipidomic profile in obesity and gestational diabetes: Evidence for sexual dimorphism
Changes in maternal blood and placental lipidomic profile in obesity and gestational diabetes: Evidence for sexual dimorphism Open
Introduction Obesity and gestational diabetes (GDM) are associated with adverse pregnancy outcomes and program the offspring for cardiometabolic disease in a sexually dimorphic manner. The placenta transfers lipids to the fetus and uses th…
View article: Data for EMSL Project 46206 from December 2018
Data for EMSL Project 46206 from December 2018 Open
View article: Multi-scale signaling and tumor evolution in high-grade gliomas
Multi-scale signaling and tumor evolution in high-grade gliomas Open
View article: Data for EMSL Project 48666 from July 2020
Data for EMSL Project 48666 from July 2020 Open
View article: Data for EMSL Project 48666 from June 2019
Data for EMSL Project 48666 from June 2019 Open
View article: Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection
Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection Open
Background Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer death among women globally. Despite advances, there is considerable variation in clinical outcomes for patients with non-luminal A tumors, …
View article: Mapping Microhabitats: Metabolome Informed Proteome Imaging of Lignocellulose Decomposition by a Naturally Evolved Microbial Consortium
Mapping Microhabitats: Metabolome Informed Proteome Imaging of Lignocellulose Decomposition by a Naturally Evolved Microbial Consortium Open
The annotated protein database was curated to annotate MS/MS data in the manuscript titled 'Mapping Microhabitats: Metabolome Informed Proteome Imaging of Lignocellulose Decomposition by a Naturally Evolved Microbial Consortium'.
View article: Mapping microhabitats of lignocellulose decomposition by a microbial consortium
Mapping microhabitats of lignocellulose decomposition by a microbial consortium Open
The leaf-cutter ant fungal garden ecosystem is a naturally evolved model system for efficient plant biomass degradation. Degradation processes mediated by the symbiotic fungus Leucoagaricus gongylophorus are difficult to characterize due t…
View article: Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions
Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer’s Disease Across Distinct Brain Regions Open
Alzheimer's disease (AD) is a neurodegenerative disease with a complex etiology influenced by confounding factors such as genetic polymorphisms, age, sex, and race. Traditionally, AD research has not prioritized these influences, resulting…
View article: Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing Open
Microglia, the innate immune cells of the central nervous system, have been genetically implicated in multiple neurodegenerative diseases. We previously mapped the genetic regulation of gene expression and mRNA splicing in human microglia,…
View article: Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health
Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health Open
Lipoproteins in cerebrospinal fluid (CSF) of the central nervous system (CNS) resemble plasma high-density lipoproteins (HDLs), which are a compositionally and structurally diverse spectrum of nanoparticles with pleiotropic functionality. …
View article: Proteogenomic insights suggest druggable pathways in endometrial carcinoma
Proteogenomic insights suggest druggable pathways in endometrial carcinoma Open
View article: TopPICR: A Companion R Package for Top-Down Proteomics Data Analysis
TopPICR: A Companion R Package for Top-Down Proteomics Data Analysis Open
Top-down proteomics is the analysis of proteins in their intact form without proteolysis, thus preserving valuable information about post-translational modifications, isoforms, and proteolytic processing. However, it is still a developing …
View article: Data for EMSL Project 51127 from April 2023
Data for EMSL Project 51127 from April 2023 Open
View article: Data for EMSL Project 47418 from February 2023
Data for EMSL Project 47418 from February 2023 Open
View article: Data for EMSL Project 46206 from February 2023
Data for EMSL Project 46206 from February 2023 Open
View article: Data for EMSL Project 46206 from February 2023
Data for EMSL Project 46206 from February 2023 Open
View article: Data for EMSL Project 51127 from February 2023
Data for EMSL Project 51127 from February 2023 Open
View article: Data for EMSL Project 48666 from May 2023
Data for EMSL Project 48666 from May 2023 Open
View article: Data for EMSL Project 48666 from May 2023
Data for EMSL Project 48666 from May 2023 Open
View article: Data for EMSL Project 48666 from May 2023
Data for EMSL Project 48666 from May 2023 Open
View article: Data for EMSL Project 48666 from February 2023
Data for EMSL Project 48666 from February 2023 Open
View article: Data for EMSL Project 46206 from February 2023
Data for EMSL Project 46206 from February 2023 Open
View article: Data for EMSL Project 51127 from May 2023
Data for EMSL Project 51127 from May 2023 Open