Elena Neumann
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View article: S100A12 correlates with inflammatory and pain symptoms in patients with chronic prostatitis/chronic pelvic pain syndrome
S100A12 correlates with inflammatory and pain symptoms in patients with chronic prostatitis/chronic pelvic pain syndrome Open
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most prevalent urological condition in men under 50, characterized by persistent or recurrent pelvic and perineal pain, and significantly reduced quality of life. Reliable b…
View article: Is low-grade inflammation related to cognitive performance during a sustained attention task in depression? – A case-control study
Is low-grade inflammation related to cognitive performance during a sustained attention task in depression? – A case-control study Open
View article: Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls
Functional resting state connectivity is differentially associated with IL-6 and TNF-α in depression and in healthy controls Open
View article: γ1 GABA<sub>A</sub>Receptors in Spinal Nociceptive Circuits
γ1 GABA<sub>A</sub>Receptors in Spinal Nociceptive Circuits Open
GABAergic neurons and GABA A receptors (GABA A Rs) are critical elements of almost all neuronal circuits. Most GABA A Rs of the CNS are heteropentameric ion channels composed of two α, two β, and one γ subunits. These receptors serve as im…
View article: Associations between peripheral cytokines, perceived fatigue and event-related potentials during a sustained attention task in depressive episodes: a case-control study
Associations between peripheral cytokines, perceived fatigue and event-related potentials during a sustained attention task in depressive episodes: a case-control study Open
This case-control study investigated the associations between peripheral inflammation, perceived fatigue, and event-related potentials (ERP) during a sustained attention test (SAT) in depression. Participants included 25 individuals with d…
View article: A phospho‐deficient α3 glycine receptor mutation alters synaptic glycine and GABA release in mouse spinal dorsal horn neurons
A phospho‐deficient α3 glycine receptor mutation alters synaptic glycine and GABA release in mouse spinal dorsal horn neurons Open
Glycine receptors (GlyRs), together with GABA A receptors, mediate postsynaptic inhibition in most spinal cord and hindbrain neurons. In several CNS regions, GlyRs are also expressed in presynaptic terminals. Here, we analysed the effects …
View article: OP0209 IMPACT OF CHRONIC INFLAMMATION AND COLLAGEN IV FRAGMENT CANSTATIN ON RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS AND ENDOTHELIAL CELL INTERACTIONS IN VITRO AND IN VIVO
OP0209 IMPACT OF CHRONIC INFLAMMATION AND COLLAGEN IV FRAGMENT CANSTATIN ON RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS AND ENDOTHELIAL CELL INTERACTIONS IN VITRO AND IN VIVO Open
View article: AB1165 ULTRASOUND AS A TOOL FOR EARLY DETECTION OF JUXTAARTICULAR NEW BONE FORMATION IN PSORIATIC ARTHRITIS AND THE ASSOCIATION OF SELECTED BIOMARKERS WITH NEW BONE FORMATION
AB1165 ULTRASOUND AS A TOOL FOR EARLY DETECTION OF JUXTAARTICULAR NEW BONE FORMATION IN PSORIATIC ARTHRITIS AND THE ASSOCIATION OF SELECTED BIOMARKERS WITH NEW BONE FORMATION Open
View article: AB0065 COMPARISON OF HISTOLOGICAL AND MOLECULAR FEATURES IN PATIENTS WITH AN ACTIVE RHEUMATOID ARTHRITIS AND PATIENTS IN REMISSION
AB0065 COMPARISON OF HISTOLOGICAL AND MOLECULAR FEATURES IN PATIENTS WITH AN ACTIVE RHEUMATOID ARTHRITIS AND PATIENTS IN REMISSION Open
View article: AB1163 INVESTIGATION OF SELECTED AUTOANTIBODIES IN PSORIATIC ARTHRITIS AND THEIR ASSOCIATION WITH COMORBIDITIES
AB1163 INVESTIGATION OF SELECTED AUTOANTIBODIES IN PSORIATIC ARTHRITIS AND THEIR ASSOCIATION WITH COMORBIDITIES Open
View article: A phosphodeficient a3 glycine receptor mutation alters synaptic glycine and GABA release in mouse spinal dorsal horn neurons
A phosphodeficient a3 glycine receptor mutation alters synaptic glycine and GABA release in mouse spinal dorsal horn neurons Open
raw data relating to the publication "A phosphodeficient a3 glycine receptor mutation alters synaptic glycine and GABA release in mouse spinal dorsal horn neurons" Abstract Glycine receptors (GlyRs), together with GABAA receptor…
View article: Predictors associated with mortality of veno-venous extracorporeal membrane oxygenation therapy
Predictors associated with mortality of veno-venous extracorporeal membrane oxygenation therapy Open
In-hospital mortality of patients receiving V-V ECMO therapy remains relatively high. Patients' outcomes have not improved significantly in the observed period. We identified age, newly detected liver failure, red blood cell transfusion an…
View article: Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical micro <scp>RNA</scp> s and activate proto‐oncogenes
Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical micro <span>RNA</span> s and activate proto‐oncogenes Open
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has a high prevalence of up to 15% and accounts for 90–95% of prostatitis diagnoses, and yet its etiopathogenesis and link to prostate cancer (PCa) are still unclear. Here, we inve…
View article: Fractional anisotropy and peripheral cytokine concentrations in outpatients with depressive episode: a diffusion tensor imaging observational study
Fractional anisotropy and peripheral cytokine concentrations in outpatients with depressive episode: a diffusion tensor imaging observational study Open
Over the past few years, evidence of a positive relationship between inflammation and depression has grown steadily. The aim of the current study was to investigate whether such depression-related inflammation could also be associated with…
View article: Plasma Leptin and Adiponectin after a 4-Week Vegan Diet: A Randomized-Controlled Pilot Trial in Healthy Participants
Plasma Leptin and Adiponectin after a 4-Week Vegan Diet: A Randomized-Controlled Pilot Trial in Healthy Participants Open
Adiponectin and leptin are important mediators of metabolic homeostasis. The actions of these adipokines extend beyond adipocytes and include systemic modulation of lipid and glucose metabolism, nutrient flux, and the immune response to ch…
View article: Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function
Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function Open
Endosome-localized Toll-like receptors (TLRs) 3 and 9 are expressed and functionally active in adipocytes. The functionality and role of TLR7 in adipocyte biology and innate immunity of adipose tissue (AT) is poorly characterized. We analy…
View article: Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis
Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis Open
View article: Modulation of Dopamine Receptors on Osteoblasts as a Possible Therapeutic Strategy for Inducing Bone Formation in Arthritis
Modulation of Dopamine Receptors on Osteoblasts as a Possible Therapeutic Strategy for Inducing Bone Formation in Arthritis Open
Rheumatoid arthritis (RA) is associated with systemic osteoporosis, which leads to severe disability and low quality of life. Current therapies target osteoclasts to reduce bone degradation, but more treatment options would be required to …
View article: Targeting the Interaction of GABAB Receptors With CHOP After an Ischemic Insult Restores Receptor Expression and Inhibits Progressive Neuronal Death
Targeting the Interaction of GABAB Receptors With CHOP After an Ischemic Insult Restores Receptor Expression and Inhibits Progressive Neuronal Death Open
GABA B receptors control neuronal excitability via slow and prolonged inhibition in the central nervous system. One important function of GABA B receptors under physiological condition is to prevent neurons from shifting into an overexcita…
View article: Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis
Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis Open
Fibroblast-like synoviocytes (FLS) play an important pathological role in persistent inflammatory joint diseases such as rheumatoid arthritis (RA). These cells have primarily been characterized in the RA synovial membrane. Here we aim to p…
View article: Systemic versus local adipokine expression differs in a combined obesity and osteoarthritis mouse model
Systemic versus local adipokine expression differs in a combined obesity and osteoarthritis mouse model Open
View article: AB0044 ENDOTHELIAL CELL AND RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLAST MIGRATION AND ADHESION ARE ALTERED BY ACTIVIN/FOLLISTATIN
AB0044 ENDOTHELIAL CELL AND RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLAST MIGRATION AND ADHESION ARE ALTERED BY ACTIVIN/FOLLISTATIN Open
View article: AB0043 EFFECT OF ANTI-INFLAMMATORY MEDICATION ON INTERACTION OF SYNOVIAL FIBROBLASTS WITH MACROPHAGES IN RHEUMATOID ARTHRITIS
AB0043 EFFECT OF ANTI-INFLAMMATORY MEDICATION ON INTERACTION OF SYNOVIAL FIBROBLASTS WITH MACROPHAGES IN RHEUMATOID ARTHRITIS Open
View article: POS0015 PREVALENCE OF NEUROPATHIES IN RHEUMATIC AND MUSCULOSKELETAL DISEASES
POS0015 PREVALENCE OF NEUROPATHIES IN RHEUMATIC AND MUSCULOSKELETAL DISEASES Open
View article: POS0844 EFFECTS OF SERIAL LOCALLY APPLIED WATER-FILTERED INFRARED A RADIATION IN PATIENTS WITH SYSTEMIC SCLEROSIS WITH SEVERE RAYNAUD'S SYNDROME RECEIVING PROSTAGLANDINE TREATMENT – A RANDOMIZED CONTROLLED TRIAL
POS0844 EFFECTS OF SERIAL LOCALLY APPLIED WATER-FILTERED INFRARED A RADIATION IN PATIENTS WITH SYSTEMIC SCLEROSIS WITH SEVERE RAYNAUD'S SYNDROME RECEIVING PROSTAGLANDINE TREATMENT – A RANDOMIZED CONTROLLED TRIAL Open
View article: A Glra3 phosphodeficient mouse mutant establishes the critical role of protein kinase A–dependent phosphorylation and inhibition of glycine receptors in spinal inflammatory hyperalgesia
A Glra3 phosphodeficient mouse mutant establishes the critical role of protein kinase A–dependent phosphorylation and inhibition of glycine receptors in spinal inflammatory hyperalgesia Open
Glycinergic neurons and glycine receptors (GlyRs) exert a critical control over spinal nociception. Prostaglandin E 2 (PGE 2 ), a key inflammatory mediator produced in the spinal cord in response to peripheral inflammation, inhibits a cert…
View article: Adipokines and Autoimmunity in Inflammatory Arthritis
Adipokines and Autoimmunity in Inflammatory Arthritis Open
Adipokines are adipose tissue-derived factors not only playing an important role in metabolism but also influencing other central processes of the body, such as inflammation. In autoimmune diseases, adipokines are involved in inflammatory …
View article: Serial whole-body cryotherapy in fibromyalgia is effective and alters cytokine profiles
Serial whole-body cryotherapy in fibromyalgia is effective and alters cytokine profiles Open
View article: Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression Open
Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arth…
View article: Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression Open
Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arth…