Edwin J. Routledge
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View article: Environmentally relevant concentrations of the tricyclic antidepressant, amitriptyline, affect feeding and reproduction in a freshwater mollusc
Environmentally relevant concentrations of the tricyclic antidepressant, amitriptyline, affect feeding and reproduction in a freshwater mollusc Open
Antidepressant drugs (ADDs) are one of the most extensively used pharmaceuticals globally. They act at particularly low therapeutic concentrations to modulate monoamine neurotransmission, which is one of the most evolutionary conserved pat…
View article: Understanding target-specific effects of antidepressant drug pollution on molluscs: A systematic review protocol
Understanding target-specific effects of antidepressant drug pollution on molluscs: A systematic review protocol Open
Background The environmental prevalence of widely prescribed human pharmaceuticals that target key evolutionary conserved biomolecules present across phyla is concerning. Antidepressants, one of the most widely consumed pharmaceuticals glo…
View article: Common aquatic pollutants modify hemocyte immune responses in Biomphalaria glabrata
Common aquatic pollutants modify hemocyte immune responses in Biomphalaria glabrata Open
Disruptions to reproductive health in wildlife species inhabiting polluted environments is often found to occur alongside compromised immunity. However, research on impacts of aquatic pollution on freshwater mollusc immune responses is lim…
View article: Uptake, Elimination and Effects of Cosmetic Microbeads on the Freshwater Gastropod Biomphalaria glabrata
Uptake, Elimination and Effects of Cosmetic Microbeads on the Freshwater Gastropod Biomphalaria glabrata Open
The presence of plastic cosmetic microbeads in the environment due to their extensive use in society and inevitable dispersal into wastewater is concerning. Therefore, it is vital to understand the processes of microplastic uptake and elim…
View article: A Comparison of Different Approaches for Characterizing Microplastics in Selected Personal Care Products
A Comparison of Different Approaches for Characterizing Microplastics in Selected Personal Care Products Open
Any uncertainty in determining numbers of microplastics in the environment may be a barrier to assessing their impact and may stem from various aspects of methodologies used to quantify them. We undertook a comparison of approaches to quan…
View article: Present-day monitoring underestimates the risk of exposure to pathogenic bacteria from cold water storage tanks
Present-day monitoring underestimates the risk of exposure to pathogenic bacteria from cold water storage tanks Open
Water-borne bacteria, found in cold water storage tanks, are causative agents for various human infections and diseases including Legionnaires' disease. Consequently, regular microbiological monitoring of tank water is undertaken as part o…
View article: Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Whole genome analysis of a schistosomiasis-transmitting freshwater snail Open
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni . With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on…
View article: Barriers to effective<i>Legionella</i>control in a changing world: a practitioner’s view
Barriers to effective<i>Legionella</i>control in a changing world: a practitioner’s view Open
Inhalation of aerosols containing Legionella pneumophila, a water-borne bacteria commonly found in natural and manmade water systems, is the main causative agent of Legionnaires' disease (LD). Approximately 10–15% of all reported cases of …
View article: Steroid Androgen Exposure during Development Has No Effect on Reproductive Physiology of Biomphalaria glabrata
Steroid Androgen Exposure during Development Has No Effect on Reproductive Physiology of Biomphalaria glabrata Open
Gastropod mollusks have been proposed as alternative models for male reproductive toxicity testing, due to similarities in their reproductive anatomy compared to mammals, together with evidence that endocrine disrupting chemicals can cause…
View article: Inactivation of <i>E. coli</i> , <i>Legionella</i> , and <i>Pseudomonas</i> in Tap Water Using Electrochemical Disinfection
Inactivation of <i>E. coli</i> , <i>Legionella</i> , and <i>Pseudomonas</i> in Tap Water Using Electrochemical Disinfection Open
Disinfection of hot water systems is critical in reducing the incidence of disease outbreaks caused by pathogenic bacteria. Electrochemical disinfection (ED) has been identified as an economical, low-maintenance and chemical-free alternati…
View article: The Nuclear Receptors of Biomphalaria glabrata and Lottia gigantea: Implications for Developing New Model Organisms
The Nuclear Receptors of Biomphalaria glabrata and Lottia gigantea: Implications for Developing New Model Organisms Open
Nuclear receptors (NRs) are transcription regulators involved in an array of diverse physiological functions including key roles in endocrine and metabolic function. The aim of this study was to identify nuclear receptors in the fully sequ…