Eyal Shahar
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View article: Migraine Age of Onset and Association With Ischemic Stroke in Late Life: 20 Years Follow-Up in ARIC
Migraine Age of Onset and Association With Ischemic Stroke in Late Life: 20 Years Follow-Up in ARIC Open
Background and Purpose: To evaluate the association between cumulative exposure to migraine and incidence of ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) study. Methods: In this ongoing, prospective longitudinal commun…
View article: Stroke mortality, clinical presentation and day of arrival: The atherosclerosis risk in communities (ARIC) study
Stroke mortality, clinical presentation and day of arrival: The atherosclerosis risk in communities (ARIC) study Open
Background. Recent studies report that acute stroke patients who present to the hospital on weekends have higher rates of 28-day mortality than similar patients who arrive during the week. However, how this association is related to clinic…
View article: Temporal trends in validated ischaemic stroke hospitalizations in the USA
Temporal trends in validated ischaemic stroke hospitalizations in the USA Open
Background: Accurate assessment of the burden of stroke, a major cause of disability and death, is crucial. We aimed to estimate rates of validated ischaemic stroke hospitalizations in the USA during 1998-2011. Methods: We used the Atheros…
View article: Trends in hospitalizations and survival of acute decompensated heart failure in four US communities (2005–2014) ARIC study community surveillance
Trends in hospitalizations and survival of acute decompensated heart failure in four US communities (2005–2014) ARIC study community surveillance Open
BACKGROUND: Community trends of acute decompensated heart failure (ADHF) in diverse populations may differ by race and sex. METHODS: The ARIC study (Atherosclerosis Risk in Communities) sampled heart failure-related hospitalizations (≥55 y…
View article: QINGDAI (QD) FOR PATIENTS WITH ACTIVE ULCERATIVE COLITIS: A RETROSPECTIVE ISRAELI NATIONAL EXPERIENCE
QINGDAI (QD) FOR PATIENTS WITH ACTIVE ULCERATIVE COLITIS: A RETROSPECTIVE ISRAELI NATIONAL EXPERIENCE Open
BACKGROUND QingDai (QD, Indigo) was shown to be effective for ulcerative colitis (UC) in randomized controlled trials and retrospective reports from Japan. However, experience with QD for UC in the West is extremely limited. We aimed to de…
View article: Validity of hospital discharge diagnosis codes for stroke: The atherosclerosis risk in communities study
Validity of hospital discharge diagnosis codes for stroke: The atherosclerosis risk in communities study Open
BACKGROUND AND PURPOSE: Characterizing International Classification of Disease 9th Revision, Clinical Modification (ICD-9-CM) code validity is essential given widespread use of hospital discharge databases in research. Using the Atheroscle…
View article: Genomewide Association Studies of Stroke
Genomewide Association Studies of Stroke Open
The genes underlying the risk of stroke in the general population remain undetermined.
View article: Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study
Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study Open
Alcohol consumption is common in the US and may confer beneficial cardiovascular effects at light-to-moderate doses. The alcohol-stroke relationship remains debated. We estimated the relationship between mid-life, self-reported alcohol con…
View article: Relation of Ventricular Premature Complexes to Heart Failure (from the Atherosclerosis Risk In Communities [ARIC] Study)
Relation of Ventricular Premature Complexes to Heart Failure (from the Atherosclerosis Risk In Communities [ARIC] Study) Open
Analogous to rapid ventricular pacing, frequent ventricular premature complexes (VPCs) may predispose over time to cardiomyopathy and subsequent heart failure (HF). We examined the association of frequent VPCs with HF incidence in a popula…
View article: Incidence and Survival of Hospitalized Acute Decompensated Heart Failure in Four US Communities (from the Atherosclerosis Risk in Communities Study)
Incidence and Survival of Hospitalized Acute Decompensated Heart Failure in Four US Communities (from the Atherosclerosis Risk in Communities Study) Open
Most population-based estimates of incident hospitalized heart failure (HF) have not differentiated acute decompensated heart failure (ADHF) from chronic stable HF nor included racially diverse populations. The Atherosclerosis Risk in Comm…
View article: Separate prediction of intracerebral hemorrhage and ischemic stroke
Separate prediction of intracerebral hemorrhage and ischemic stroke Open
OBJECTIVES: To develop and validate 10-year cumulative incidence functions of intracerebral hemorrhage (ICH) and ischemic stroke (IS). METHODS: We used data on 27,493 participants from 3 population-based cohort studies: the Atherosclerosis…
View article: Association between physical activity and risk of stroke subtypes: The Atherosclerosis Risk in Communities (ARIC) Study
Association between physical activity and risk of stroke subtypes: The Atherosclerosis Risk in Communities (ARIC) Study Open
The relationship between stroke subtypes and physical activity is unclear.
View article: Airflow obstruction, lung function, and risk of incident heart failure: the Atherosclerosis Risk in Communities (ARIC) study
Airflow obstruction, lung function, and risk of incident heart failure: the Atherosclerosis Risk in Communities (ARIC) study Open
We examined the relationship between forced expiratory volume in 1 s (FEV1), airflow obstruction, and incident heart failure (HF) in black and white, middle-aged men and women in four US communities.
View article: A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study
A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study Open
Previous studies have speculated that the higher stroke incidence rate in blacks compared with whites may be due, in part, to stroke risk factors exerting a more adverse effect among blacks than whites. To determine whether such racial dif…
View article: Classification of Heart Failure in the Atherosclerosis Risk in Communities (ARIC) Study: A Comparison of Diagnostic Criteria
Classification of Heart Failure in the Atherosclerosis Risk in Communities (ARIC) Study: A Comparison of Diagnostic Criteria Open
Population-based research on heart failure (HF) is hindered by lack of consensus on diagnostic criteria. Framingham (FRM), National Health and Nutrition Examination Survey (NHANES), Modified Boston (MBS), Gothenburg (GTH), and Internationa…
View article: Prediction of Incident Heart Failure in General Practice: The Atherosclerosis Risk in Communities (ARIC) Study
Prediction of Incident Heart Failure in General Practice: The Atherosclerosis Risk in Communities (ARIC) Study Open
A simple and effective heart failure (HF) risk score would facilitate the primary prevention and early diagnosis of HF in general practice. We examined the external validity of existing HF risk scores, optimized a 10-year HF risk function,…
View article: Classification of Acute Decompensated Heart Failure: An Automated Algorithm Compared With a Physician Reviewer Panel: The Atherosclerosis Risk in Communities Study
Classification of Acute Decompensated Heart Failure: An Automated Algorithm Compared With a Physician Reviewer Panel: The Atherosclerosis Risk in Communities Study Open
An algorithm to classify heart failure (HF) endpoints inclusive of contemporary measures of biomarkers and echocardiography was recently proposed by an international expert panel. Our objective was to assess agreement of HF classification …
View article: HDL-Cholesterol and Incidence of Breast Cancer in the ARIC Cohort Study
HDL-Cholesterol and Incidence of Breast Cancer in the ARIC Cohort Study Open
An association of low plasma HDL-cholesterol with risk of breast cancer has been suggested by multiple studies; the evidence, however, is not conclusive. We examined the possible association of low HDL-cholesterol with incidence of breast …
View article: Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study
Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study Open
Prospective data evaluating abnormal sleep quality and quantity with cognitive decline are limited because most studies used subjective data and/or had short follow-up. We hypothesized that, over 15 y of follow-up, participants with object…
View article: Redistribution of heart failure as the cause of death: the Atherosclerosis Risk in Communities Study
Redistribution of heart failure as the cause of death: the Atherosclerosis Risk in Communities Study Open
Background Heart failure is sometimes incorrectly listed as the underlying cause of death (UCD) on death certificates, thus compromising the accuracy and comparability of mortality statistics. Statistical redistribution of the UCD has been…
View article: Temporal trends in validated ischaemic stroke hospitalizations in the USA
Temporal trends in validated ischaemic stroke hospitalizations in the USA Open
Background Accurate assessment of the burden of stroke, a major cause of disability and death, is crucial. We aimed to estimate rates of validated ischaemic stroke hospitalizations in the USA during 1998–2011. Methods We used the Atheroscl…
View article: Project Reliability Engineering
Project Reliability Engineering Open
Drawing loosely from disciplines found in large software companies, this book distills the practices of DevOps and Site Reliability Engineering (SRE) and addresses issues that matter to makers: keeping projects up and running, and providin…
View article: Trends in Hospitalizations and Survival of Acute Decompensated Heart Failure in Four US Communities (2005–2014)
Trends in Hospitalizations and Survival of Acute Decompensated Heart Failure in Four US Communities (2005–2014) Open
Background: Community trends of acute decompensated heart failure (ADHF) in diverse populations may differ by race and sex. Methods: The ARIC study (Atherosclerosis Risk in Communities) sampled heart failure-related hospitalizations (≥55 y…
View article: Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study
Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study Open
Introduction This study tested the hypotheses that late‐midlife obstructive sleep apnea (OSA) and short and long sleep duration are associated with dementia over 15 years of follow‐up. Methods A total of 1667 Atherosclerosis Risk in Commun…
View article: A Theorem at the Core of Colliding Bias
A Theorem at the Core of Colliding Bias Open
Conditioning on a shared outcome of two variables can alter the association between these variables, possibly adding a bias component when estimating effects. In particular, if two causes are marginally independent, they might be dependent…