Eyal Shemesh
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View article: Cardiovascular Precision Medicine and Remote Intervention Trial Rationale and Design
Cardiovascular Precision Medicine and Remote Intervention Trial Rationale and Design Open
Background: It has recently been shown that excessive fluctuation in blood pressure readings for an individual over time is closely associated with poor outcomes, including increased risk of cardiovascular mortality, coronary heart disease…
View article: Prevalence of contraindicated combinations amid behavioral and mental health medications filled in a pediatric population
Prevalence of contraindicated combinations amid behavioral and mental health medications filled in a pediatric population Open
Background Behavioral or mental health disorders are common in children, adolescents, and young adults. Medication use is increasingly common, with few data describing drug-drug combinations in ambulatory settings. The objectives of this s…
View article: The improving Medication Adherence in Adolescents and young adults following Liver Transplantation (iMALT) multisite trial: Design and trial implementation considerations
The improving Medication Adherence in Adolescents and young adults following Liver Transplantation (iMALT) multisite trial: Design and trial implementation considerations Open
Background/aims Medication non-adherence is a leading cause of transplant rejection, organ loss, and death; yet no rigorous controlled study to date has shown compelling clinical benefits from an adherence-improving intervention. Non-adher…
View article: Acceleration of mobile health for monitoring post‐transplant in the COVID‐19 era: Applications for pediatric settings
Acceleration of mobile health for monitoring post‐transplant in the COVID‐19 era: Applications for pediatric settings Open
Background Since the start of the COVID‐19 pandemic and consequent lockdowns, the use of telehealth interventions has rapidly increased both in the general population and among transplant recipients. Among pediatric transplant recipients, …
View article: The Utility of a Pre-Transplant Psychosocial Evaluation in Predicting Post-Liver Transplant Outcomes
The Utility of a Pre-Transplant Psychosocial Evaluation in Predicting Post-Liver Transplant Outcomes Open
Background: There is insufficient evidence about the ability of pretransplant psychosocial evaluations to predict posttransplant outcomes. While standardized assessments were developed to increase predictive validity, it is unclear whether…
View article: Approaches to Research Determination of Late Acute Cellular Rejection in Pediatric Liver Transplant Recipients
Approaches to Research Determination of Late Acute Cellular Rejection in Pediatric Liver Transplant Recipients Open
A central pathology or site reading of biopsy slides is used in liver transplant clinical trials to determine rejection. We evaluated interrater reliability of readings of “rejection or not” using digitized slides from the Medication Adher…
View article: Association Between Neighborhood-level Socioeconomic Deprivation and the Medication Level Variability Index for Children Following Liver Transplantation
Association Between Neighborhood-level Socioeconomic Deprivation and the Medication Level Variability Index for Children Following Liver Transplantation Open
Background. Neighborhood socioeconomic deprivation is associated with adverse health outcomes. We sought to determine if neighborhood socioeconomic deprivation was associated with adherence to immunosuppressive medications after liver tran…
View article: Weekend versus weekday adherence: Do we, or do we not, thank God it’s Friday?
Weekend versus weekday adherence: Do we, or do we not, thank God it’s Friday? Open
Adherence monitoring and intervention studies do not show improvements in clinical outcomes: why, and what can be done about it? Boucquemont et al's article is on page 274. Adherence monitoring and intervention studies do not show improvem…
View article: A learning health network for pediatric liver transplantation: Inaugural meeting report from the Starzl Network for Excellence in Pediatric Transplantation
A learning health network for pediatric liver transplantation: Inaugural meeting report from the Starzl Network for Excellence in Pediatric Transplantation Open
Learning Health Networks (LHN) improve the well‐being of populations by aligning clinical care specialists, technology experts, patients and patient advocates, and other thought leaders for continuous improvement and seamless care delivery…
View article: Perceived barriers to medication adherence remain stable following solid organ transplantation
Perceived barriers to medication adherence remain stable following solid organ transplantation Open
Perceived barriers to adherence have previously been investigated in SOT to identify plausible intervention targets to improve adherence and transplant outcomes. Fifteen centers in CTOTC enrolled patients longitudinally. Patients >8 years …
View article: A systematic review of immunosuppressant adherence interventions in transplant recipients: Decoding the streetlight effect
A systematic review of immunosuppressant adherence interventions in transplant recipients: Decoding the streetlight effect Open
Non‐adherence to immunosuppressant medications is an important risk factor for graft dysfunction. To evaluate the effectiveness of adherence‐enhancing interventions, we reviewed adherence intervention studies in solid organ transplant reci…
View article: Recruiting a representative sample in adherence research—The <scp>MALT</scp> multisite prospective cohort study experience
Recruiting a representative sample in adherence research—The <span>MALT</span> multisite prospective cohort study experience Open
Medication adherence is an important determinant of transplant outcomes. Attempts to investigate adherence are frequently undermined by selection bias: It is very hard to recruit and retain non‐adherent patients in research efforts. This m…
View article: Trajectory of adherence behavior in pediatric and adolescent liver transplant recipients: The medication adherence in children who had a liver transplant cohort
Trajectory of adherence behavior in pediatric and adolescent liver transplant recipients: The medication adherence in children who had a liver transplant cohort Open
Knowledge of the longterm trajectory of nonadherence to immunosuppressants can inform decisions regarding organ allocation, adherence monitoring, and intervention efforts. The Medication Adherence in Children Who Had a Liver Transplant (MA…
View article: Medication adherence and rejection rates in older vs younger adult liver transplant recipients
Medication adherence and rejection rates in older vs younger adult liver transplant recipients Open
A growing number of older adults are undergoing liver transplantation ( LT ) in the United States. In some settings, it is thought that adherence declines with age. This retrospective study examined adherence and clinical outcomes in older…
View article: Methodological Comments on “The Stanford Integrated Psychosocial Assessment for Transplantation: A Prospective Study of Medical and Psychosocial Outcomes”
Methodological Comments on “The Stanford Integrated Psychosocial Assessment for Transplantation: A Prospective Study of Medical and Psychosocial Outcomes” Open
Division of Behavioral and Developmental Health, The Department of Pediatrics and Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York, NY Received for publication January 15, 2016; revision received January 23, 20…
View article: Suicidal Ideation During the Postpartum Period
Suicidal Ideation During the Postpartum Period Open
Findings suggest that SI among a relatively healthy group of new mothers occurs with some frequency. Mothers with a history of depression and antepartum complications may be at increased risk.