Eun Sun Kim
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View article: Impact of Cranioplasty Timing and Status on Long-Term Survival and Functional Outcomes After Decompressive Craniectomy for Severe Traumatic Brain Injury
Impact of Cranioplasty Timing and Status on Long-Term Survival and Functional Outcomes After Decompressive Craniectomy for Severe Traumatic Brain Injury Open
Background: Decompressive craniectomy (DC) is a life-saving procedure for severe traumatic brain injury (TBI); however, its long-term outcomes remain controversial. Cranioplasty traditionally performed to restore cranial integrity, has bee…
View article: The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models
The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models Open
Hepatocellular carcinoma (HCC) requires novel therapeutic targets, and oncofetal genes offer a promising avenue. Although the adaptor protein AP2M1 is a known prognostic factor in HCC, its functional role in promoting cancer stemness remai…
View article: Clinical Efficacy of Real-Time Artificial Intelligence-Assisted Colonoscopy in Colorectal Polyp Detection: A Prospective Multicenter Randomized Controlled Trial
Clinical Efficacy of Real-Time Artificial Intelligence-Assisted Colonoscopy in Colorectal Polyp Detection: A Prospective Multicenter Randomized Controlled Trial Open
Real-time CADe-assisted colonoscopy significantly increased PDR and ADR and proved to be a strong independent predictor of adenoma detection (cris.nih.go.kr, KCT0009664).
View article: AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients
AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients Open
Acute myeloid leukemia (AML) is a complex hematological malignancy characterized by chemotherapy resistance, leading to poor patient outcomes. This study investigates the role of adaptor protein complex 2 subunit mu 1 (AP2M1) in hematopoie…
View article: Clinical and Radiological Predictors for Early Hematoma Expansion After Spontaneous Intracerebral Hemorrhage: A Retrospective Study
Clinical and Radiological Predictors for Early Hematoma Expansion After Spontaneous Intracerebral Hemorrhage: A Retrospective Study Open
Background: Early hematoma expansion is a major determinant of poor outcomes after spontaneous intracerebral hemorrhage (ICH). Identifying reliable predictors of hematoma expansion may facilitate risk stratification and timely intervention…
View article: Evanescent-Field-Guiding 2D Ultrathin Waveguides for Seamlessly Integrated Devices
Evanescent-Field-Guiding 2D Ultrathin Waveguides for Seamlessly Integrated Devices Open
Seamless integration of active devices into photonic integrated circuits remains a challenge due to the limited accessibility of the optical field in conventional waveguides, which tightly confine light within their cores. In this study, w…
View article: Genetic Artificial Intelligence in Gastrointestinal Disease: A Systematic Review
Genetic Artificial Intelligence in Gastrointestinal Disease: A Systematic Review Open
Background/Objectives: The application of predictive and explainable artificial intelligence to bioinformatics data such as single nucleotide polymorphism (SNP) information is attracting rising attention in the diagnosis of various disease…
View article: Factors Affecting Low Health‐Related Quality of Life and Health Issues in Gastric Cancer Survivors: A Propensity Score‐Matched, Nationwide Study
Factors Affecting Low Health‐Related Quality of Life and Health Issues in Gastric Cancer Survivors: A Propensity Score‐Matched, Nationwide Study Open
Background and Aim This study evaluated the health‐related quality of life (HRQoL) of Korean gastric cancer survivors (GCSs) aged ≥ 19 years using preference‐based measurements with a converted health utility index. Methods Data from the f…
View article: Gene expression network analysis identified CDK1 and KIF11 as possible key molecules in the development of colorectal cancer from normal tissues
Gene expression network analysis identified CDK1 and KIF11 as possible key molecules in the development of colorectal cancer from normal tissues Open
Background Colorectal cancer (CRC) is one of the most common malignancies and the second most common cause of cancer-related mortality worldwide. Despite extensive research, the mechanism underlying CRC development remains unclear. This st…
View article: A Case of IgG4-Related Disease of Gastrointestinal Origin Suspected to be Lymphoma and Actinomyces Infection
A Case of IgG4-Related Disease of Gastrointestinal Origin Suspected to be Lymphoma and Actinomyces Infection Open
Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by the tendency to form tumefactive lesions. However, the disease has highly variable clinical manifestations, as IgG4-RD can affect any organ. The …
View article: Solute carrier family 2 member 2 (glucose transporter 2): a common factor of hepatocyte and hepatocellular carcinoma differentiation
Solute carrier family 2 member 2 (glucose transporter 2): a common factor of hepatocyte and hepatocellular carcinoma differentiation Open
GLUT2 (SLC2A2), a vital glucose transporter in liver, pancreas, and kidney tissues, regulates blood glucose levels and energy metabolism. Beyond its metabolic role, SLC2A2 contributes to cell differentiation and metabolic adaptation during…
View article: Receptor-ligand interactions for optimized endocytosis in targeted therapies
Receptor-ligand interactions for optimized endocytosis in targeted therapies Open
Receptor-mediated endocytosis plays a crucial role in the success of numerous therapies and remains central to advancing drug development. This process begins with ligand binding to specific receptors, triggering the internalization and in…
View article: Asparaginase-Associated Pancreatitis and Pancreatic Pseudocyst Managed with Endoscopic Cystogastrostomy in Adult Acute Lymphoblastic Leukemia
Asparaginase-Associated Pancreatitis and Pancreatic Pseudocyst Managed with Endoscopic Cystogastrostomy in Adult Acute Lymphoblastic Leukemia Open
Anticancer treatment for acute lymphocytic leukemia is based on drugs such as methotrexate, 6-mercaptopurine, vincristine, and asparaginase. Asparaginase-related pancreatitis is known to have an incidence of up to 18%, and is a major cause…
View article: Survey of the Actual Practices Used for Endoscopic Removal of Colon Polyps in Korea: A Comparison with the Current Guidelines
Survey of the Actual Practices Used for Endoscopic Removal of Colon Polyps in Korea: A Comparison with the Current Guidelines Open
Adherence to the guidelines for endoscopic resection techniques varied depending on the characteristics of colorectal polyps. Thus, an individualized approach is required to increase adherence to the guidelines.
View article: P0296 Comparison of clinical characteristics of Montreal classification group A3 patients with Crohn’s disease in Korea: Results from the Prospective and Retrospective CONNECT Study
P0296 Comparison of clinical characteristics of Montreal classification group A3 patients with Crohn’s disease in Korea: Results from the Prospective and Retrospective CONNECT Study Open
Background The CONNECT study, a nationwide multicenter cohort study of Crohn’s disease (CD) in Korea, was designed to investigate the clinical characteristics and long-term prognosis of CD patients. Starting in 2009, the study enrolled pat…
View article: P0845 Safety and Adverse Events of the Adjuvanted Herpes Zoster Vaccine (Shingrix) in Inflammatory Bowel Disease Patients: A Comparison of Age Groups Under and Over 50 Years
P0845 Safety and Adverse Events of the Adjuvanted Herpes Zoster Vaccine (Shingrix) in Inflammatory Bowel Disease Patients: A Comparison of Age Groups Under and Over 50 Years Open
Background This study investigates the safety profile of the adjuvanted herpes zoster (HZ) vaccine (Shingrix) in patients with inflammatory bowel disease (IBD), particularly comparing adverse events (AEs) in those under 50 years old versus…
View article: Generative Artificial Intelligence in the Early Diagnosis of Gastrointestinal Disease
Generative Artificial Intelligence in the Early Diagnosis of Gastrointestinal Disease Open
This study reviews the recent progress of generative artificial intelligence for gastrointestinal disease (GID) from detection to diagnosis. The source of data was 16 original studies in PubMed. The search terms were ((gastro* [title]) or …
View article: Ionizing radiation inhibits zebrafish embryo hatching through induction of tissue inhibitors of metalloproteinases ( <scp>TIMP</scp> s) expression
Ionizing radiation inhibits zebrafish embryo hatching through induction of tissue inhibitors of metalloproteinases ( <span>TIMP</span> s) expression Open
Ionizing radiation (IR) has garnered growing attention because of its biological effects on aquatic organisms and humans. Here, we identify the most impacted organs and uncover the molecular mechanisms causing the changes in the context of…
View article: Investigating the Impact of Stagger Angle on Double Suction Pump Performance through Computational Fluid Dynamics
Investigating the Impact of Stagger Angle on Double Suction Pump Performance through Computational Fluid Dynamics Open
The double suction pump (DSP) is a centrifugal pump variant widely utilized in applications requiring higher head ( H ) and volumetric flow rates of fluid, owing to its ability to deliver robust performance under such conditions. In this s…
View article: A Novel Retractable Robotic Device for Colorectal Endoscopic Submucosal Dissection
A Novel Retractable Robotic Device for Colorectal Endoscopic Submucosal Dissection Open
: The dissection speed and safety profile improved significantly with the retractable RESD. Thus, our robotic device has the potential to provide simple, effective, and safe multidirectional traction during colonic ESD.
View article: Artificial intelligence in colonoscopy: from detection to diagnosis
Artificial intelligence in colonoscopy: from detection to diagnosis Open
This study reviews the recent progress of artificial intelligence for colonoscopy from detection to diagnosis. The source of data was 27 original studies in PubMed. The search terms were “colonoscopy” (title) and “deep learning” (abstract)…
View article: Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment
Colon cancer: the 2023 Korean clinical practice guidelines for diagnosis and treatment Open
Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic m…
View article: A survey of current practices in post-polypectomy surveillance in Korea
A survey of current practices in post-polypectomy surveillance in Korea Open
Background/Aims: We investigated the clinical practice patterns of post-polypectomy colonoscopic surveillance among Korean endoscopists.Methods: In a web-based survey conducted between September and November 2021, participants were asked a…