Gabrielle Potocki-Véronèse
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View article: Biochemical characterization of a SusD-like protein involved in β-1,3-glucan utilization by an uncultured cow rumen <i>Bacteroides</i>
Biochemical characterization of a SusD-like protein involved in β-1,3-glucan utilization by an uncultured cow rumen <i>Bacteroides</i> Open
In ruminants, the rumen is a specialized stomach that is adapted to the breakdown of plant-derived complex polysaccharides through the coordinated activities of a diverse microbial community. Bacteroidota is a major phylum in this bovine r…
View article: Unravelling the structure-function of a tandem pair of glycoside transporters in the marine flavobacterium Zobellia galactanivorans Dsij T
Unravelling the structure-function of a tandem pair of glycoside transporters in the marine flavobacterium Zobellia galactanivorans Dsij T Open
International audience
View article: Functional exploration of in vivo and in vitro lignocellulose-fed rumen bacterial microbiomes reveals novel enzymes involved in polysaccharide breakdown
Functional exploration of in vivo and in vitro lignocellulose-fed rumen bacterial microbiomes reveals novel enzymes involved in polysaccharide breakdown Open
Background: Plant cell walls are the main carbon sources for ruminal bacteria, which have evolved to produce sophisticated multi-functional enzyme cocktails in response to the structural diversity of lignocelulloses. Since a large proporti…
View article: <i>O</i>-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases
<i>O</i>-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases Open
Inflammatory bowel diseases (IBD) are modern diseases, with incidence rising around the world. They are associated with perturbation of the intestinal microbiota, and with alteration and crossing of the mucus barrier by the commensal bacte…
View article: Supplementary Data for "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase"
Supplementary Data for "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase" Open
This dataset contains atomic coordinates of the molecular dynamics simulations described in "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase" by M. Alfonso-Prieto, I. Cuxart, G. Poto…
View article: Supplementary Data for "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase"
Supplementary Data for "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase" Open
This dataset contains atomic coordinates of the molecular dynamics simulations described in "Substrate-Assisted Mechanism for the Degradation of N-glycans by a Gut Bacterial Mannoside Phosphorylase" by M. Alfonso-Prieto, I. Cuxart, G. Poto…
View article: Helical Inclusion Complexes of Amylose with Aromatic Compounds: Crystallographic Evidence for New V-Type Allomorphs
Helical Inclusion Complexes of Amylose with Aromatic Compounds: Crystallographic Evidence for New V-Type Allomorphs Open
International audience
View article: Structural and Biochemical Characterization of a Nonbinding SusD-Like Protein Involved in Xylooligosaccharide Utilization by an Uncultured Human Gut <i>Bacteroides</i> Strain
Structural and Biochemical Characterization of a Nonbinding SusD-Like Protein Involved in Xylooligosaccharide Utilization by an Uncultured Human Gut <i>Bacteroides</i> Strain Open
The metabolization of dietary fiber is a crucial function for many gut bacteria, especially Bacteroidetes , which are particularly well adapted for recognizing, binding, transporting, and degrading glycosides. In this study, we report the …
View article: Identification of Glycoside Transporters From the Human Gut Microbiome
Identification of Glycoside Transporters From the Human Gut Microbiome Open
Transport is a crucial step in the metabolism of glycosides by bacteria, which is itself key for microbiota function and equilibrium. However, most transport proteins are function-unknown or only predicted, limiting our understanding of ho…
View article: Discovery and Biotechnological Exploitation of Glycoside-Phosphorylases
Discovery and Biotechnological Exploitation of Glycoside-Phosphorylases Open
Among carbohydrate active enzymes, glycoside phosphorylases (GPs) are valuable catalysts for white biotechnologies, due to their exquisite capacity to efficiently re-modulate oligo- and poly-saccharides, without the need for costly activat…
View article: Peer Review #3 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.2)"
Peer Review #3 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.2)" Open
The earth harbors a trillion bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition.Most of the genes responsible for these functions are found among nonculturable bacteria and are still to b…
View article: Peer Review #1 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.2)"
Peer Review #1 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.2)" Open
The earth harbors a trillion bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition.Most of the genes responsible for these functions are found among nonculturable bacteria and are still to b…
View article: Peer Review #2 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)"
Peer Review #2 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)" Open
The earth harbors a trillion bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition.Most of the genes responsible for these functions are found among nonculturable bacteria and are still to b…
View article: MINTIA: a metagenomic INserT integrated assembly and annotation tool
MINTIA: a metagenomic INserT integrated assembly and annotation tool Open
The earth harbors trillions of bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition. Most of the genes responsible for these functions belong to uncultured bacteria and are still to be disc…
View article: Peer Review #1 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)"
Peer Review #1 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)" Open
The earth harbors a trillion bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition.Most of the genes responsible for these functions are found among nonculturable bacteria and are still to b…
View article: Peer Review #3 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)"
Peer Review #3 of "MINTIA: a metagenomic INserT integrated assembly and annotation tool (v0.1)" Open
The earth harbors a trillion bacterial species adapted to very diverse ecosystems thanks to specific metabolic function acquisition.Most of the genes responsible for these functions are found among nonculturable bacteria and are still to b…
View article: α-Galactosidase and Sucrose-Kinase Relationships in a Bi-functional AgaSK Enzyme Produced by the Human Gut Symbiont Ruminococcus gnavus E1
α-Galactosidase and Sucrose-Kinase Relationships in a Bi-functional AgaSK Enzyme Produced by the Human Gut Symbiont Ruminococcus gnavus E1 Open
Plant α-galactosides belonging to the raffinose family oligosaccharides (RFOs) and considered as prebiotics, are commonly degraded by α-galactosidases produced by the human gut microbiome. In this environment, the Ruminococcus gnavus E1 sy…
View article: Analysis of the diversity of the glycoside hydrolase family 130 in mammal gut microbiomes reveals a novel mannoside-phosphorylase function
Analysis of the diversity of the glycoside hydrolase family 130 in mammal gut microbiomes reveals a novel mannoside-phosphorylase function Open
Mannoside phosphorylases are involved in the intracellular metabolization of mannooligosaccharides, and are also useful enzymes for the in vitro synthesis of oligosaccharides. They are found in glycoside hydrolase family GH130. Here we rep…
View article: A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment
A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment Open
Background The rumen microbiota provides essential services to its host and, through its role in ruminant production, contributes to human nutrition and food security. A thorough knowledge of the genetic potential of rumen microbes will pr…
View article: Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria
Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria Open
Prebiotics are increasingly used as food supplements, especially in infant formulas, to modify the functioning and composition of the microbiota. However, little is currently known about the mechanisms of prebiotic recognition and transpor…
View article: Additional file 2 of Investigating host-microbiome interactions by droplet based microfluidics
Additional file 2 of Investigating host-microbiome interactions by droplet based microfluidics Open
Additional file 2. Table S3. Functional and taxonomical annotation of the metagenomic sequences.
View article: Investigating Host Microbiota Relationships Through Functional Metagenomics
Investigating Host Microbiota Relationships Through Functional Metagenomics Open
The human Intestinal mucus is formed by glycoproteins, the O- and N-linked glycans which constitute a crucial source of carbon for commensal gut bacteria, especially when deprived of dietary glycans of plant origin. In recent years, a doze…
View article: Sucrose 6F-phosphate phosphorylase: a novel insight in the human gut microbiome
Sucrose 6F-phosphate phosphorylase: a novel insight in the human gut microbiome Open
The human gut microbiome plays an essential role in maintaining human health including in degradation of dietary fibres and carbohydrates further used as nutrients by both the host and the gut bacteria. Previously, we identified a polysacc…
View article: <i>In Vitro</i> Synthesis and Crystallization of β-1,4-Mannan
<i>In Vitro</i> Synthesis and Crystallization of β-1,4-Mannan Open
In vitro polymerization of β-mannans is a challenging reaction due to the steric hindrance confered by the configuration of mannosyl residues and the thermodynamic instability of the β-anomer. Whatever the approach used to date-whether che…
View article: Highly Promiscuous Oxidases Discovered in the Bovine Rumen Microbiome
Highly Promiscuous Oxidases Discovered in the Bovine Rumen Microbiome Open
The bovine rumen hosts a diverse microbiota, which is highly specialized in the degradation of lignocellulose. Ruminal bacteria, in particular, are well equipped to deconstruct plant cell wall polysaccharides. Nevertheless, their potential…
View article: Two new gene clusters involved in the degradation of plant cell wall from the fecal microbiota of Tunisian dromedary
Two new gene clusters involved in the degradation of plant cell wall from the fecal microbiota of Tunisian dromedary Open
Dromedaries are capable of digesting plant cell wall with high content of lignocellulose of poor digestibility. Consequently, their intestinal microbiota can be a source of novel carbohydrate-active enzymes (CAZymes). To the best of our kn…