Einar Wilder‐Smith
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View article: Immune triggers preceding neuralgic amyotrophy
Immune triggers preceding neuralgic amyotrophy Open
Background and purpose Infections and vaccinations have been identified as potential immunological triggers of neuralgic amyotrophy (NA), but the exact type and frequency of the preceding agents is unknown. Methods This was a multicentre, …
View article: Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy
Relapsing-Remitting Immunotherapy Responsive Small-Fiber Neuropathy Open
This is a single observational study without controls. This provides Class IV evidence.
View article: Neuropathies related to hepatitis E virus infection: A prospective, matched case–control study
Neuropathies related to hepatitis E virus infection: A prospective, matched case–control study Open
Background Acute hepatitis E virus (HEV) infection has recently emerged as a potential trigger for acute dysimmune neuropathies, but prospective controlled studies are lacking. Aims To compare the frequency of concomitant acute HEV infecti…
View article: Neuromuscular ultrasound standardized scanning techniques and protocols: Expert panel recommendations
Neuromuscular ultrasound standardized scanning techniques and protocols: Expert panel recommendations Open
Neuromuscular ultrasound has become an integral part of the diagnostic workup of neuromuscular disorders at many centers. Despite its growing utility, uniform standard scanning techniques do not currently exist. Scanning approaches for sim…
View article: Lower Motoneuron Dysfunction Impacts Spontaneous Motor Recovery in Acute Cervical Spinal Cord Injury
Lower Motoneuron Dysfunction Impacts Spontaneous Motor Recovery in Acute Cervical Spinal Cord Injury Open
Paresis after spinal cord injury (SCI) is caused by damage to upper and lower motoneurons (LMNs) and may differentially impact neurological recovery. This prospective monocentric longitudinal observational study investigated the extent and…
View article: Novel Autoantibodies in Idiopathic Small Fiber Neuropathy
Novel Autoantibodies in Idiopathic Small Fiber Neuropathy Open
Objective Small fiber neuropathy (SFN) is clinically and etiologically heterogeneous. Although autoimmunity has been postulated to be pathophysiologically important in SFN, few autoantibodies have been described. We aimed to identify autoa…
View article: Small fiber neuropathy: Swiss cohort characterization
Small fiber neuropathy: Swiss cohort characterization Open
Introduction/Aim There is currently insufficient clinical and epidemiological data concerning small fiber neuropathy (SFN). This research analyzes data from medical records to determine epidemiology, demographics, clinical characteristics …
View article: Safety and tolerability of cryocompression as a method of enhanced limb hypothermia to reduce taxane-induced peripheral neuropathy
Safety and tolerability of cryocompression as a method of enhanced limb hypothermia to reduce taxane-induced peripheral neuropathy Open
Purpose Severe peripheral neuropathy is a common dose-limiting toxicity of taxane chemotherapy, with no effective treatment. Frozen gloves have shown to reduce the severity of neuropathy in several studies but comes with the incidence of u…
View article: Teaching Video NeuroImages: Hourglass-like fascicular constriction in Parsonage-Turner syndrome
Teaching Video NeuroImages: Hourglass-like fascicular constriction in Parsonage-Turner syndrome Open
A 43-year-old woman presented with intense pain in the left upper arm, a plegic flexor pollicis longus, and flexor digitorum profundus of the 2nd digit without sensory symptoms occurring 8 days after a hysterectomy. Needle myography showed…
View article: Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study
Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study Open
This study suggests that continuous limb hypothermia accompanying paclitaxel infusion may reduce paclitaxel-induced PN and have therapeutic potential in select patients and warrants further investigation. The method is safe and well tolera…
View article: Clinical Reasoning: Temporal profile of inflammatory neuropathies
Clinical Reasoning: Temporal profile of inflammatory neuropathies Open
A 52-year-old man presented with acute onset of weakness and paresthesias involving all 4 extremities in 2008 preceded by an episode of viral catarrh 3 weeks prior. Examination revealed symmetrical upper and lower extremity weakness (Medic…
View article: Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy
Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy Open
Low NDRG1 expression in nerve tissue present within samples of surgical resection may identify subjects at risk for severe paclitaxel-induced neuropathy. Since nerve biopsies are not routinely feasible for patients undergoing chemotherapy …
View article: Neurological Manifestations of Leprosy
Neurological Manifestations of Leprosy Open
Neurological Manifestations of Leprosy
View article: Radial nerve torsion
Radial nerve torsion Open
Peripheral nerve torsion is increasingly recognized due to the widespread availability of nerve ultrasound imaging.1,2 A 31-year-old man presented with acute onset complete left wrist drop after prolonged sleeping on his outwardly rotated …
View article: Localising Median Neuropathies: The Role of Different Investigations
Localising Median Neuropathies: The Role of Different Investigations Open
Answer: BA 50-year-old male with diabetic nephropathy and renal failure on maintenance haemodialysis through a left arterio-venous fi stula was referred to the Neuroscience Clinic with pain, numbness and tingling over the lateral 3 fi nger…
View article: Hypothermia for preventing chemotherapy-induced neuropathy – a pilot study on safety and tolerability in healthy controls
Hypothermia for preventing chemotherapy-induced neuropathy – a pilot study on safety and tolerability in healthy controls Open
Our results confirm the safety and tolerability of continuous flow limb hypothermia in healthy subjects. Further studies will use 22 °C thermoregulator temperature to investigate hypothermia in preventing CIPN in breast cancer patients rec…
View article: Clinical Reasoning: Burning hands and feet
Clinical Reasoning: Burning hands and feet Open
A 25-year-old banker, a nonsmoker and nondrinker, presented with pain in the hands and feet for 4 weeks that progressed to involve shoulders and hips. Pain was associated with constipation, followed by diarrhea. He had no prior trauma, vac…
View article: Nonadherence to treatment causing acute hospitalizations in people with epilepsy
Nonadherence to treatment causing acute hospitalizations in people with epilepsy Open
To the Editors: With interest we have read the article “Nonadherence to treatment causing acute hospitalizations in people with epilepsy: An observational, prospective study.”2014 In this study, nonadherence was present when the C/D (conce…