E.A. Carlini
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View article: Clinical study of Pfaffia glomerata (Spreng.) Pedersen on healthy middle-aged and elderly men: assessment of the effects on cognition
Clinical study of Pfaffia glomerata (Spreng.) Pedersen on healthy middle-aged and elderly men: assessment of the effects on cognition Open
Pfaffia glomerata (Spreng.) Pedersen (PG) has potential effects on cognitive function, yet it has not been studied in humans. This randomized, double-blinded, placebo-controlled study investigated the effect of PG roots standardized extrac…
View article: 10.01 Prostanoid-insensitive chimeric antigen receptor modified T cells mediate therapeutic efficacy in solid cancer models
10.01 Prostanoid-insensitive chimeric antigen receptor modified T cells mediate therapeutic efficacy in solid cancer models Open
Background Chimeric antigen receptor (CAR) T cell therapy has transformed the landscape of hematologic malignancy treatment. However, its successful translation to solid cancer treatment remains challenging, primarily due to the immunosupp…
View article: Toxicology evaluation of Pfaffia glomerata (Spreng.) Pedersen root extract in rats
Toxicology evaluation of Pfaffia glomerata (Spreng.) Pedersen root extract in rats Open
Pfaffia glomerata (Spreng.) Pedersen (PG) is one of the species referred to as 'Brazilian ginseng', widely commercialized in Brazil. Acute and repeated dose toxicological evaluations of PG lyophilized root extract was conducted in young ma…
View article: 193P Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibit anti-cancer immunity via CCL2
193P Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibit anti-cancer immunity via CCL2 Open
Overexpression of sialic acids on glycans, called hypersialylation is a common alteration found in cancer. Hypersialylation can, for example, enhance immune evasion via interaction with sialic acid-binding immunoglobulin-like lectin (Sigle…
View article: Anticholinesterase and Pro-dopaminergic Effects of Instant Coffee
Anticholinesterase and Pro-dopaminergic Effects of Instant Coffee Open
Epidemiologic studies suggest an inverse correlation between coffee consumption and the occurrence of neurodegenerative diseases, but the role of caffeine and roasting degree are still matter of debate. The objective of this work was to ev…
View article: Green coffee extract attenuates Parkinson’s-related behaviors in animal models
Green coffee extract attenuates Parkinson’s-related behaviors in animal models Open
Epidemiological studies have shown an inverse association between coffee consumption and the development of Parkinson’s disease (PD). The present investigation aimed to evaluate the effects of caffeine and green (non-roasted) coffee extrac…
View article: From an Alternative Medicine to a New Treatment for Refractory Epilepsies: Can Cannabidiol Follow the Same Path to Treat Neuropsychiatric Disorders?
From an Alternative Medicine to a New Treatment for Refractory Epilepsies: Can Cannabidiol Follow the Same Path to Treat Neuropsychiatric Disorders? Open
Although cannabis has been known for ages as an “alternative medicine” to provide relief from seizures, pain, anxiety, and inflammation, there had always been a limited scientific review to prove and establish its use in clinics. Early stu…
View article: Green Coffee Extract Blockades Haloperidol-Induced Catalepsy and Contralateral Rotations Induced by Apomorphine After Unilateral 6-OHDA Lesion on Striatum
Green Coffee Extract Blockades Haloperidol-Induced Catalepsy and Contralateral Rotations Induced by Apomorphine After Unilateral 6-OHDA Lesion on Striatum Open
Epidemiological studies have shown an inverse association between coffee consumption and the development of Parkinson’s disease (PD). The present investigation aimed to evaluate the effects of caffeine and green (non-roasted) coffee extrac…
View article: Impact of the Training of Professionals from São Paulo Public Health System in Phytotherapy Practice
Impact of the Training of Professionals from São Paulo Public Health System in Phytotherapy Practice Open
Introduction: Following the introduction in 2006 of the National Policy on Integrative and Complementary Practices, and The National Policy on Medicinal Plants and Herbal Medicines, the Municipal Secretariat for the Environment of the City…
View article: Impact of the Training of Professionals from São Paulo Public Health System in Phytotherapy Practice
Impact of the Training of Professionals from São Paulo Public Health System in Phytotherapy Practice Open
Introduction: Following the introduction in 2006 of the National Policy on Integrative and Complementary Practices, and The National Policy on Medicinal Plants and Herbal Medicines, the Municipal Secretariat for the Environment of the City…
View article: Impacto da Capacitação de Profissionais da Rede Pública de Saúde de São Paulo na Prática da Fitoterapia
Impacto da Capacitação de Profissionais da Rede Pública de Saúde de São Paulo na Prática da Fitoterapia Open
Introduction: Following the introduction in 2006 of the National Policy on Integrative and Complementary Practices, and The National Policy on Medicinal Plants and Herbal Medicines, the Municipal Secretariat for the Environment of the City…
View article: Enkephalin related peptides are released from jejunum wall by orally ingested bromelain
Enkephalin related peptides are released from jejunum wall by orally ingested bromelain Open
Stem bromelain [EC 3.4.22.32] is a thiol-endopeptidase and orally recommended in traditional medicine due to its analgesic activity, but the mechanisms are not known. Proenkephalin is expressed in the nervous system, but also in the gastro…
View article: Issue Information
Issue Information Open
No abstract is available for this article.
View article: Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol
Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol Open
Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure act…
View article: Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol
Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol Open
Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure act…
View article: Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010
Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010 Open
OBJECTIVE To analyze temporal trends of the prevalence of alcohol and tobacco use among Brazilian students. METHODS We analyzed data published between 1989 and 2010 from five epidemiological surveys on students from the 6th to the 12th gra…
View article: The association of psychiatric symptomatology with patterns of alcohol, tobacco, and marijuana use among Brazilian high school students
The association of psychiatric symptomatology with patterns of alcohol, tobacco, and marijuana use among Brazilian high school students Open
Background and Objectives: Studies have highlighted psychosocial factors associated with drug use among adolescents. Association of specific psychiatric comorbidity with substance use has not been properly established in Brazil. This study…
View article: Phytochemical analysis of hydroethanolic extract of Turnera diffusa Willd and evaluation of its effects on astrocyte cell death
Phytochemical analysis of hydroethanolic extract of Turnera diffusa Willd and evaluation of its effects on astrocyte cell death Open
Objective To evaluate the phytochemical composition of hydroethanolic extracts from powdered aerial parts of Turnera diffusa Willd (Turneraceae; T. diffusa), as well as its toxicity in astrocytes. Methods Chemical analyses of hydroethanoli…
View article: PHYTOCHEMICAL ANALYSIS OF HYDROETHANOLIC EXTRACTS FROM POWDERED ROOTS OF<i>Panax ginseng</i>C. A. Meyer AND<i>Heteropterys tomentosa</i>A. Juss AND EVALUATION OF THEIR EFFECTS ON ASTROCYTE CELL DEATH
PHYTOCHEMICAL ANALYSIS OF HYDROETHANOLIC EXTRACTS FROM POWDERED ROOTS OF<i>Panax ginseng</i>C. A. Meyer AND<i>Heteropterys tomentosa</i>A. Juss AND EVALUATION OF THEIR EFFECTS ON ASTROCYTE CELL DEATH Open
The medicinal plants Panax ginseng C. A. Meyer (Araliaceae) and Heteropterys tomentosa A. Juss (Malpighiaceae) are widely and separately used by the Brazilian population as phytotherapeutics for the same medicinal purposes as tonics and to…