Eric C. Chen
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View article: Examining Online Caregiving Discussions Across Racial Groups of Informal Alzheimer’s Disease Caregivers
Examining Online Caregiving Discussions Across Racial Groups of Informal Alzheimer’s Disease Caregivers Open
Alzheimer’s Disease and Related Dementias (ADRD) create significant burdens for informal caregivers, with previous studies indicating higher strain among Black caregivers due to socioeconomic disparities. This study analyzed ten years of o…
View article: LLM-Generated Personalized Analogies to Foster AI Literacy in Adult Novices
LLM-Generated Personalized Analogies to Foster AI Literacy in Adult Novices Open
Broad Al literacy is essential in today's rapidly advancing technological landscape, extending beyond Al specialists to encompass the general public. However, the complexity of Al concepts poses significant barriers to learning for individ…
View article: Vibe-Eval: A hard evaluation suite for measuring progress of multimodal language models
Vibe-Eval: A hard evaluation suite for measuring progress of multimodal language models Open
We introduce Vibe-Eval: a new open benchmark and framework for evaluating multimodal chat models. Vibe-Eval consists of 269 visual understanding prompts, including 100 of hard difficulty, complete with gold-standard responses authored by e…
View article: Reka Core, Flash, and Edge: A Series of Powerful Multimodal Language Models
Reka Core, Flash, and Edge: A Series of Powerful Multimodal Language Models Open
We introduce Reka Core, Flash, and Edge, a series of powerful multimodal language models trained from scratch by Reka. Reka models are able to process and reason with text, images, video, and audio inputs. This technical report discusses d…
View article: Asian American University Students’ Experiences during the COVID-19 Pandemic: A Qualitative Study
Asian American University Students’ Experiences during the COVID-19 Pandemic: A Qualitative Study Open
In addition to the unprecedented challenges and stressors that university students faced during the COVID-19 pandemic, Asian American students experienced specific hardships due to COVID-19-associated xenophobic attitudes, harassment, and …
View article: Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions
Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions Open
This repository contains the annotations, analyses and scripts used to create the figures for the dikaryotic strains of R. irregularis chromosome assemblies.
View article: Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions
Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions Open
This repository contains the annotations, analyses and scripts used to create the figures for the dikaryotic strains of R. irregularis chromosome assemblies.
View article: Faculty experiences and motivations in design thinking teaching and learning
Faculty experiences and motivations in design thinking teaching and learning Open
Introduction: Design thinking (DT) is a creative, iterative approach to generating solutions that are desirable, feasible, and viable. Given its role in fostering creativity and innovation, a growing number of higher education instructors …
View article: Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions
Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions Open
Arbuscular mycorrhizal fungi (AMF) are prominent root symbionts with a multinucleate cytoplasm that can carry thousands of nuclei deriving from two parental strains and varying in relative abundance in a large syncytium. Here, we set out t…
View article: Long reads and Hi-C sequencing illuminate the two compartment genome of the model arbuscular mycorrhizal symbiont <i>Rhizophagus irregularis</i>
Long reads and Hi-C sequencing illuminate the two compartment genome of the model arbuscular mycorrhizal symbiont <i>Rhizophagus irregularis</i> Open
Chromosome folding links genome structure with gene function by generating distinct nuclear compartments and topologically associating domains (TADs). In mammals, these undergo preferential interactions and regulate gene expression. Howeve…
View article: Long reads and Hi-C sequencing illuminate the two-compartment genome of the model arbuscular mycorrhizal symbiont Rhizophagus irregularis
Long reads and Hi-C sequencing illuminate the two-compartment genome of the model arbuscular mycorrhizal symbiont Rhizophagus irregularis Open
This repository contains annotations for the strains of R. irregularis chromosome assemblies.
View article: Long reads and Hi-C sequencing illuminate the two-compartment genome of the model arbuscular mycorrhizal symbiont Rhizophagus irregularis
Long reads and Hi-C sequencing illuminate the two-compartment genome of the model arbuscular mycorrhizal symbiont Rhizophagus irregularis Open
This repository contains annotations for the strains of R. irregularis chromosome assemblies.
View article: GapPredict: A Language Model for Resolving Gaps in Draft Genome Assemblies
GapPredict: A Language Model for Resolving Gaps in Draft Genome Assemblies Open
Short-read DNA sequencing instruments can yield over 1e+12 bases per run, typically composed of reads 150 bases long. Despite this high throughput, de novo assembly algorithms have difficulty reconstructing contiguous genome sequences usin…
View article: More Filtering on SNP Calling Does Not Remove Evidence of Inter-Nucleus Recombination in Dikaryotic Arbuscular Mycorrhizal Fungi
More Filtering on SNP Calling Does Not Remove Evidence of Inter-Nucleus Recombination in Dikaryotic Arbuscular Mycorrhizal Fungi Open
Evidence for the existence of dikaryote-like strains, low nuclear sequence diversity and inter-nuclear recombination in arbuscular mycorrhizal fungi has been recently reported based on single nucleus sequencing data. Here, we aimed to supp…
View article: More filtering on SNP calling does not remove evidence of inter-nucleus recombination in dikaryotic arbuscular mycorrhizal fungi
More filtering on SNP calling does not remove evidence of inter-nucleus recombination in dikaryotic arbuscular mycorrhizal fungi Open
We respond to a recent reanalysis of single nucleus sequence data from Chen et al. 2018 eLife , which indicated that evidence of inter-nuclear recombination in dikaryotic arbuscular mycorrhizal fungi decreases when heterozygous, duplicated…
View article: Abstract 74: Inactivation of Cntnap4 in Cranial Neural Crest Cells Results in Craniofacial Bone Deformities and Hydrocephalus
Abstract 74: Inactivation of Cntnap4 in Cranial Neural Crest Cells Results in Craniofacial Bone Deformities and Hydrocephalus Open
PURPOSE: Contactin-associated protein-like 4 (Cntnap4) is a member of the neurexin superfamily of transmembrane molecules that have critical functions in neuronal cell communication. For example, global Cntnap4 knockout mice exhibit autism…
View article: Comparative genomics of <i>Rhizophagus irregularis</i>,<i> R. cerebriforme</i>,<i> R. diaphanus</i> and <i>Gigaspora rosea</i> highlights specific genetic features in Glomeromycotina
Comparative genomics of <i>Rhizophagus irregularis</i>,<i> R. cerebriforme</i>,<i> R. diaphanus</i> and <i>Gigaspora rosea</i> highlights specific genetic features in Glomeromycotina Open
Summary Glomeromycotina is a lineage of early diverging fungi that establish arbuscular mycorrhizal ( AM ) symbiosis with land plants. Despite their major ecological role, the genetic basis of their obligate mutualism remains largely unkno…
View article: Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi
Single nucleus sequencing reveals evidence of inter-nucleus recombination in arbuscular mycorrhizal fungi Open
Eukaryotes thought to have evolved clonally for millions of years are referred to as ancient asexuals. The oldest group among these are the arbuscular mycorrhizal fungi (AMF), which are plant symbionts harboring hundreds of nuclei within o…
View article: Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis
Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis Open
Contactin-associated protein-like 4 (Cntnap4) is a member of the neurexin superfamily of transmembrane molecules that have critical functions in neuronal cell communication. Cntnap4 knockout mice display decreased presynaptic gamma-aminobu…