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View article: Can polycythaemia vera disease be predicted from haematologic parameters? A machine learning-based study
Can polycythaemia vera disease be predicted from haematologic parameters? A machine learning-based study Open
Aims The aim of this research is to diagnose polycythaemia vera (PV) disease using different machine learning (ML) algorithms with complete blood count (CBC) parameters before further investigations such as Janus kinase 2 ( JAK2 ), erythro…
View article: Challenging Clinical Therapeutic Approach to Urticarial Vasculitis: A Case Series
Challenging Clinical Therapeutic Approach to Urticarial Vasculitis: A Case Series Open
Background: Urticarial vasculitis (UV) is a rare form of small-vessel vasculitis characterized by persistent urticarial lesions and systemic manifestations. It differs from chronic spontaneous urticaria (CSU) both clinically and pathogenet…
View article: Etiologic evaluation of male patients diagnosed with anemia in the first consultation of the hematology department
Etiologic evaluation of male patients diagnosed with anemia in the first consultation of the hematology department Open
Aims: Anemia is a decrease in hemoglobin (Hb) levels below the normal values determined by gender. Since anemia is a laboratory finding, its etiology must be investigated. The present study aimed to investigate the etiologic spectrum of ma…
View article: Effects of extracorporeal photopheresis on survival in chronic graft versus host disease
Effects of extracorporeal photopheresis on survival in chronic graft versus host disease Open
Objective: Chronic graft versus host disease (cGVHD) develops after allogeneic hematopoietic cell transplantation, when immune cells from a non-identical donor initiate an immune reaction against the transplant recipient. Extracorporeal ph…
View article: Management of Primary Immune Thrombocytopenia – Turkish Modified Delphi-Based Consensus Statement for Special Considerations
Management of Primary Immune Thrombocytopenia – Turkish Modified Delphi-Based Consensus Statement for Special Considerations Open
As the National ITP Study Group, we have observed the need to increase the practice guidance regarding patients with primary ITP requiring additional treatments including invasive interventions and co-treatments for coagulation. Decisions …
View article: The role of therapeutic plasma exchange in the treatment of patients with septic shock- single center experience
The role of therapeutic plasma exchange in the treatment of patients with septic shock- single center experience Open
Aims: Sepsis is a life-threatening organ dysfunction resulting from an excessive inflammatory response in the host due to infection. Due to the activation of the coagulation system in sepsis, the search for treatment has shifted in this di…
View article: Prophylactic intravenous immunoglobulin use in allogeneic stem cell transplantation; does intravenous immunoglobulin affect survival, sepsis, and engraftment time?
Prophylactic intravenous immunoglobulin use in allogeneic stem cell transplantation; does intravenous immunoglobulin affect survival, sepsis, and engraftment time? Open
BACKGROUND: Stem cell transplant recipients have an increase in various infections depending on the immunosuppression. The purpose is to explore the effect of the use of proflactıc intravenous immunoglobulin (IVIG) on transplant recıpıents…
View article: Retrospective evaluation of indications for therapeutic plasmapheresis procedures applied in our center
Retrospective evaluation of indications for therapeutic plasmapheresis procedures applied in our center Open
Aims: Therapeutic plasma exchange (TPE) is a process in which pathological substances (autoantibodies, alloantibodies, immune complexes, lipoproteins, cryoglobulins, etc.) in the patient's plasma are removed from the body along with the pa…
View article: Management of Adult Primary Immune Thrombocytopenia: Delphi- Based Consensus Recommendations
Management of Adult Primary Immune Thrombocytopenia: Delphi- Based Consensus Recommendations Open
The optimization of the dose and duration of TPO-RAs in addition to corticosteroids is necessary to improve the management of patients with pITP.
View article: Evaluation of busulfan, cyclophosphamide, and etoposide as a preparation regimen for autologous stem cell transplantation in Hodgkin’s lymphoma patients
Evaluation of busulfan, cyclophosphamide, and etoposide as a preparation regimen for autologous stem cell transplantation in Hodgkin’s lymphoma patients Open
BACKGROUND: Hodgkin’s lymphoma (HL) exhibits a cure rate of 90% in patients diagnosed at an early stage and a cure rate ranging from 70% to 90% in patients diagnosed at an advanced stage. In the case of patients with relapsed/refractory HL…
View article: The Experience of Ibrutinib in Chronic Graft-Versus-Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: Single Center Experience
The Experience of Ibrutinib in Chronic Graft-Versus-Host Disease in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: Single Center Experience Open
Introduction:Chronic graft-versus host disease (GVHD) is a serious complication that develops in 35-50% of patients in the late period after allogeneic hematopoetic stem cell transplantation. About half of the patients are resistant to cor…
View article: Unmet clinical needs and challenges in the management of acute leukemia in Turkey: a modified Delphi study
Unmet clinical needs and challenges in the management of acute leukemia in Turkey: a modified Delphi study Open
Aim: To determine the unmet needs and challenges in management, diagnosis, treatment, follow-up and patient-physician communication in acute leukemia (AL). Materials & methods: The study was based on a modified Delphi approach. A questionn…
View article: A case of malignant melanoma presented with lombar vertebra fracture
A case of malignant melanoma presented with lombar vertebra fracture Open
Aims: Malignant melanoma is a type of skin cancer with a very poor prognosis. It is the most common skin cancer. Metastases are frequently observed in malignant melanoma, which can have a very aggressive course, even without skin findings.…
View article: Effect of tyrosine kinase inhibitor and conventional chemotherapy on COVID 19 antibody level in hematological patients
Effect of tyrosine kinase inhibitor and conventional chemotherapy on COVID 19 antibody level in hematological patients Open
Aims: In this study, we aim to discover if there is a difference between COVID 19 antibody level in hematological patients taking conventional chemotherapy and tyrosin kinase inhibitors. Methods: COVİD 19 IgG levels were measured using the…
View article: The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma
The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma Open
Objective: The aim of this study is to investigate the effect of the preemptive use of plerixafor in patients with lymphoma and multiple myeloma which was administered as a preemptive single dose to the patients who were determined to have…
View article: How are the Results of Allogeneic Stem Cell Transplantation in Elderly Patients? A Single-center Experience
How are the Results of Allogeneic Stem Cell Transplantation in Elderly Patients? A Single-center Experience Open
Aim: In this study, we aimed to present allogeneic hematopoietic stem cell transplantation (allo-HSCT) experience in elderly patients with hematological malignancy.Materials and methods: Thirty-five patients aged 60 years and older who und…
View article: Identification of lymphocyte subgroups with flow cytometry in COVID-19 patients
Identification of lymphocyte subgroups with flow cytometry in COVID-19 patients Open
Objective: We aimed to determine lymphocyte subgroups and activation status of flow cytometry in COVID-19 patients and examine their relationship with disease stage and length of hospital stay.Material and Method: Forty patients were analy…
View article: Identification of lymphocyte subgroups with flow cytometry in COVID-19 patients
Identification of lymphocyte subgroups with flow cytometry in COVID-19 patients Open
Objective: We aimed to determine lymphocyte subgroups and activation status of flow cytometry in COVID-19 patients and examine their relationship with disease stage and length of hospital stay. Material and Method: Forty patients were anal…
View article: The effect of cryopreserved and noncryopreserved stem cells on the outcome of autologous stem-cell transplantation in multiple myeloma patients
The effect of cryopreserved and noncryopreserved stem cells on the outcome of autologous stem-cell transplantation in multiple myeloma patients Open
Background The CD34+ stem cells are either noncryopreserved (non-CP) or cryopreserved (CP) in autologous stem-cell transplantation (ASCT). Some retrospective studies have shown that engraftment failure and engraftment rate are similar in C…
View article: Turkey Real-Life Data: Demographic Features, Treatment Results and Effects of Comorbidities in Chronic Myeloid Leukemia
Turkey Real-Life Data: Demographic Features, Treatment Results and Effects of Comorbidities in Chronic Myeloid Leukemia Open
The response rates of CP-CML patients to the tyrosine kinase inhibitors were satisfactory. In addition to tolerability and side effect profiles of drugs, comorbidity status of patients should also be considered in treatment choice in CML p…
View article: The frequency of HLA A, B, C, DP, DQ, DR allele in patients of Turkish and Syrian nationals with allogeneic stem cell transplantation
The frequency of HLA A, B, C, DP, DQ, DR allele in patients of Turkish and Syrian nationals with allogeneic stem cell transplantation Open
BACKGROUND: In allogeneic stem cell transplantation, donor and recipient HLA tissue compatibility is essential for the success of stem cell transplantation. HLA tissue compatibility percentage is the most important parameter that increases…
View article: Convalescent plasma therapy in COVID-19
Convalescent plasma therapy in COVID-19 Open
The coronavirus disease 2019 (COVID‐19) affected many people in a short time and 5-10% of them were severely affected by the disease. A variety of treatment methods have been developed for this rapidly spreading disease and vaccine studies…
View article: Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia
Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia Open
The aim is this study was to make the etiological classification of patients diagnosed with TMA in our region and to statistically evaluate the effect of therapeutic plasma exchange, which we use in treatment, on laboratory recovery and mo…