Ebtesam Al‐Olayan
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View article: Retraction Note: Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles
Retraction Note: Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles Open
View article: Evaluation of acute nephrotoxicity induced by CuO nanosheet as a nanopesticide through TNF-α and NF-kB up-regulation
Evaluation of acute nephrotoxicity induced by CuO nanosheet as a nanopesticide through TNF-α and NF-kB up-regulation Open
Nanoparticles have gained prominence in the formulation of nanopesticides, leveraging their unique nanocharacteristics. This study delves into the nephrotoxic implications of CuONanoSheet (CuONS), as nanopesticide tailored for agricultural…
View article: In-depth characterization of virulence traits, pathogenicity, antibiogram, and antibiotic resistance genes of MDR Vibrio parahaemolyticus retrieved from shrimp
In-depth characterization of virulence traits, pathogenicity, antibiogram, and antibiotic resistance genes of MDR Vibrio parahaemolyticus retrieved from shrimp Open
V. parahaemolyticus poses a remarkable public health threat, accounting for approximately 25% of global seafood-related infections in human consumers and resulting in severe infections and substantial economic losses in the aquaculture. To…
View article: Physicochemical, Microbiological and Sensory Evaluation of Plant-Based Meat Analogs Supplemented with Phenolic Extracts from Olive Mill By-Products
Physicochemical, Microbiological and Sensory Evaluation of Plant-Based Meat Analogs Supplemented with Phenolic Extracts from Olive Mill By-Products Open
The bioactive properties of a phenolic extract (PE) obtained from olive mill vegetation water (OVW) in powder formulation were utilized to enrich a meat analog composed of lentils and champignon mushrooms. The primary phenolic compounds in…
View article: Effects of Tick Infestation on Milk Yield, Blood Biochemistry, Hematology, and the Overall Health of Dairy Cows
Effects of Tick Infestation on Milk Yield, Blood Biochemistry, Hematology, and the Overall Health of Dairy Cows Open
Tick infestation represents a significant constraint on livestock productivity in Saudi Arabia; however, there remains a substantial gap in research addressing tick species diversity, distribution, and their direct effects on milk producti…
View article: Impact of diverse irrigation water sources on olive oil quality and its physicochemical, fatty acids, antioxidant, and antibacterial properties
Impact of diverse irrigation water sources on olive oil quality and its physicochemical, fatty acids, antioxidant, and antibacterial properties Open
This study investigates the impact of irrigation water sources on the quality of olive oil from the Chemlal olive variety in the Hadjadj region, northeast of Mostaganem, Algeria, a coastal area known for its semi-arid climate and intensive…
View article: Assessment of the Nutritional Composition, Antimicrobial Potential, Anticoccidial, and Antioxidant Activities of Arthospira platensis in Broilers
Assessment of the Nutritional Composition, Antimicrobial Potential, Anticoccidial, and Antioxidant Activities of Arthospira platensis in Broilers Open
This study evaluates the chemical composition, fatty acid profiles, and bioactive properties of ethanolic (SPE), methanolic (SPM), and acetonic (SPA) extracts of Arthrospira platensis. The chemical analysis revealed a high protein content …
View article: Exploration of the anticancer efficacy of a novel 1,3-thiazole analog in an ehrlich ascites carcinoma model: <i>in vivo</i> and <i>in silico</i> insights into hepatorenal protective potentials <i>via</i> the modulation of apoptosis, oxidative stress and inflammation
Exploration of the anticancer efficacy of a novel 1,3-thiazole analog in an ehrlich ascites carcinoma model: <i>in vivo</i> and <i>in silico</i> insights into hepatorenal protective potentials <i>via</i> the modulation of apoptosis, oxidative stress and inflammation Open
Delving into the multifaceted therapeutical potential of BTHP as a novel 1,3-thiazole-based anticancer agent.
View article: Evaluation of Probiotic Potential and Functional Properties of Lactobacillus Strains Isolated from Dhan, Traditional Algerian Goat Milk Butter
Evaluation of Probiotic Potential and Functional Properties of Lactobacillus Strains Isolated from Dhan, Traditional Algerian Goat Milk Butter Open
Goat milk butter, locally known as “Dhan”, from the Sfisfa region of Algeria, holds significant cultural and economic value. This study investigates the probiotic properties of lactic acid bacteria (LAB) present in Dhan, focusing particula…
View article: Antimicrobial Activity of Arthrospira platensis-Mediated Gold Nanoparticles against Streptococcus pneumoniae: A Metabolomic and Docking Study
Antimicrobial Activity of Arthrospira platensis-Mediated Gold Nanoparticles against Streptococcus pneumoniae: A Metabolomic and Docking Study Open
The emergence of antibiotic-resistant Streptococcus pneumoniae necessitates the discovery of novel therapeutic agents. This study investigated the antimicrobial potential of green-synthesized gold nanoparticles (AuNPs) fabricated using Art…
View article: Comparative LC–MS-based metabolite profiling, antioxidant, and antibacterial properties of Bunium bulbocastanum tubers from two regions in Algeria
Comparative LC–MS-based metabolite profiling, antioxidant, and antibacterial properties of Bunium bulbocastanum tubers from two regions in Algeria Open
View article: Novel Insights into the Antimicrobial and Antibiofilm Activity of Pyrroloquinoline Quinone (PQQ); In Vitro, In Silico, and Shotgun Proteomic Studies
Novel Insights into the Antimicrobial and Antibiofilm Activity of Pyrroloquinoline Quinone (PQQ); In Vitro, In Silico, and Shotgun Proteomic Studies Open
Microbial infections pose a significant global health threat, affecting millions of individuals and leading to substantial mortality rates. The increasing resistance of microorganisms to conventional treatments requires the development of …
View article: Supplementation of Saussurea costus root alleviates sodium nitrite-induced hepatorenal toxicity by modulating metabolic profile, inflammation, and apoptosis
Supplementation of Saussurea costus root alleviates sodium nitrite-induced hepatorenal toxicity by modulating metabolic profile, inflammation, and apoptosis Open
Sodium nitrite (NaNO 2 ) is a widely used food ingredient, although excessive concentrations can pose potential health risks. In the present study, we evaluated the deterioration effects of NaNO 2 additives on hematology, metabolic profile…
View article: Impact of Nanoencapsulated Rosemary Essential Oil as a Novel Feed Additive on Growth Performance, Nutrient Utilization, Carcass Traits, Meat Quality and Gene Expression of Broiler Chicken
Impact of Nanoencapsulated Rosemary Essential Oil as a Novel Feed Additive on Growth Performance, Nutrient Utilization, Carcass Traits, Meat Quality and Gene Expression of Broiler Chicken Open
This study evaluated the effect of free and nanoencapsulated rosemary essential oil (REO) as an antibiotic alternative in broiler diets on growth performance, nutrient digestibility, carcass traits, meat quality and gene expression. Four h…
View article: Synthesis and antiproliferative evaluation of novel 3,5,8-trisubstituted coumarins against breast cancer
Synthesis and antiproliferative evaluation of novel 3,5,8-trisubstituted coumarins against breast cancer Open
Aim: This study focused on designing and synthesizing novel derivatives of 3,5,8-trisubstituted coumarin. Results: The synthesized compounds, particularly compound 5, exhibited significant cytotoxic effects on MCF-7 ce…
View article: Correlation between Aerosol Particulates, Carcass Dirtiness, and Hygiene Indicators of Bovine Carcasses in the Abattoir Environment: Results of a Study in Italy
Correlation between Aerosol Particulates, Carcass Dirtiness, and Hygiene Indicators of Bovine Carcasses in the Abattoir Environment: Results of a Study in Italy Open
The objective of this study was to demonstrate the possible correlation of visible carcass contamination and abattoir aerosol quality with microbial hygiene criteria. A total of 279 bovine carcasses were analyzed on 23 different working da…
View article: Serum 25-Hydroxyvitamin D Is Inversely Associated with Nasopharyngeal Carcinoma: A Hospital-Based Matched Case–Control Study in Malaysia
Serum 25-Hydroxyvitamin D Is Inversely Associated with Nasopharyngeal Carcinoma: A Hospital-Based Matched Case–Control Study in Malaysia Open
Serum 25(OH)D deficiency consistently demonstrated molecular mechanisms through which chronic inflammation is associated with the risk of nasopharyngeal carcinoma (NPC). This study aimed to determine the association between serum 25(OH)D a…
View article: An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine
An insight review on the neuropharmacological effects, mechanisms of action, pharmacokinetics and toxicity of mitragynine Open
Mitragynine is one of the main psychoactive alkaloids in Mitragyna speciosa Korth. (kratom). It has opium-like effects by acting on μ-, δ-, and κ-opioid receptors in the brain. The compound also interacts with other receptors, such as adre…
View article: Molecular identification of Fasciola species based on ribosomal and mitochondrial DNA sequences in Riyadh, Saudi Arabia
Molecular identification of Fasciola species based on ribosomal and mitochondrial DNA sequences in Riyadh, Saudi Arabia Open
Fasciola species are the causative agents of liver fluke disease (fasciolosis) which is primarily found in domestic and wild ruminants but also are causal agents of fascioliasis in humans. Few reports for the genotyping of Fasciola species…
View article: Prevelance of Bovine Cysticercosis in Egypt and the Cysticidal Effect of Two Extracts Obtained from &lt;i&gt;Balanites aegyptiaca&lt;/i&gt; and &lt;i&gt;Moringa oleifera&lt;/i&gt; on Mice Model Affected with &lt;i&gt;T. saginata&lt;/i&gt; Cysticerci
Prevelance of Bovine Cysticercosis in Egypt and the Cysticidal Effect of Two Extracts Obtained from <i>Balanites aegyptiaca</i> and <i>Moringa oleifera</i> on Mice Model Affected with <i>T. saginata</i> Cysticerci Open
The aim of the present study was to determine the prevalence of bovine cysticercosis in both cattle and buffloas, in Egypt and to assess the cysticidal efficacy of Balanites aegyptiaca fruits (B. aegyptiaca) and Moringa oleifera seeds (M. …
View article: Biochemical Liver Functions and Molecular Identification of &lt;i&gt;Fasciola&lt;/i&gt; &lt;i&gt;hepatica&lt;/i&gt; from Experimentally Infected Rat Model
Biochemical Liver Functions and Molecular Identification of <i>Fasciola</i> <i>hepatica</i> from Experimentally Infected Rat Model Open
The current study was performed to evaluate the liver function status as well as molecular characterization of the recovered worms in rats experimentally infected with F. hepatica. Sixteen male Wister rats aged 30 days were randomly alloca…
View article: Therapeutic effectiveness of Ferula asafetida against Hymenolepis nana
Therapeutic effectiveness of Ferula asafetida against Hymenolepis nana Open
Hymenolepis nana is a common intestinal tapeworm that affects humans. Drugs, including praziquantel (PZQ), are essential for managing this infection. Natural products are now considered as an alternative agent to control hymenolepiasis. Th…
View article: Novel 8-Methoxycoumarin-3-Carboxamides with potent anticancer activity against liver cancer via targeting caspase-3/7 and β-tubulin polymerization
Novel 8-Methoxycoumarin-3-Carboxamides with potent anticancer activity against liver cancer via targeting caspase-3/7 and β-tubulin polymerization Open
View article: Serum 25-hydroxyvitamin D and nasopharyngeal carcinoma risk and survival: a hospital-based matched prospective case-control study in Malaysia
Serum 25-hydroxyvitamin D and nasopharyngeal carcinoma risk and survival: a hospital-based matched prospective case-control study in Malaysia Open
Serum 25(OH) D deficiency may be one of the underlying molecular mechanisms through which chronic inflammation is associated with risk and survival of nasopharyngeal carcinoma (NPC). This study was conducted to determine the association be…
View article: New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study
New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study Open
A new series of thiazolyl-pyrazoline derivatives (4a–d, 5a–d 6a, b, 7a–d, 8a, b, and 10a, b) have been designed and synthesized through the combination of thiazole and pyrazoline moieties, starting from the key building blocks pyrazoline c…
View article: Boosting Mouse Defense against Lethal Toxoplasma gondii Infection with Full-Length and Soluble SAG1 Recombinant Protein
Boosting Mouse Defense against Lethal Toxoplasma gondii Infection with Full-Length and Soluble SAG1 Recombinant Protein Open
Toxoplasmosis is a major worldwide protozoan zoonosis. The surface antigen 1 (SAG1) of Toxoplasma gondii (T. gondii) has always been recognized as an ideal vaccine candidate antigen. However, the intact and soluble SAG1 protein is usually …
View article: ADAMTS-13 and HMGB1-induced oxidative stress in Taenia multiceps-infected animals
ADAMTS-13 and HMGB1-induced oxidative stress in Taenia multiceps-infected animals Open
This study investigated the cytotoxic effects of oxidative stress (OS), high mobility group box 1 (HMGB1), ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs), and neuropathology associated with coenurus cerebralis ( Ta…
View article: Potential role of biosynthesized silver nanoparticles from Aaronsohnia factorovskyi on Hymenolepis nana in BALB/c mice
Potential role of biosynthesized silver nanoparticles from Aaronsohnia factorovskyi on Hymenolepis nana in BALB/c mice Open
Hymenolepiasis is the most common intestinal tapeworm infection in humans caused by an intestinal cestode, Hymenolepis nana. Praziquantel (PZQ) is the most effective drug among other compounds, however, many cases of drug resistance have b…
View article: Exploring consumer perception of entomophagy by applying the Rasch model: data from an online survey
Exploring consumer perception of entomophagy by applying the Rasch model: data from an online survey Open
An online consumer survey, consisting of 23 closed questions divided into 9 sections, was conducted to investigate consumer perception of including edible insects in their diet. The data analysis was carried out using a variation of the cl…
View article: In vivo Evaluation of the Antiviral Effects of Arabian Coffee (Coffea arabica) and Green Tea (Camellia sinensis) Extracts on Influenza A Virus
In vivo Evaluation of the Antiviral Effects of Arabian Coffee (Coffea arabica) and Green Tea (Camellia sinensis) Extracts on Influenza A Virus Open
This in vivo study was conducted to evaluate the antiviral activity of Arabian coffee (Coffea arabica) and green tea (Camellia sinensis) extracts against the influenza virus. High-performance liquid chromatography (HPLC) was used to determ…