F. T. Perkins
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View article: The response to oral poliovaccine in persons aged 16–18 years
The response to oral poliovaccine in persons aged 16–18 years Open
SUMMARY Serum neutralizing antibodies to polioviruses were titrated in serum samples from 182 police cadets aged 16–18 years before and, in 168 of the cadets, 6 weeks after vaccination with a single dose of oral polio vaccine (OPV). Faecal…
View article: Towards a Taxonomic System
Towards a Taxonomic System Open
This book is the first report of the activities of the International Committee on Nomen- clature of Viruses (I.C.N.V
View article: The British reference preparation for influenza virus haemagglutinin
The British reference preparation for influenza virus haemagglutinin Open
SUMMARY The two methods for measuring the haemagglutinin content of an influenza virus suspension are the haemagglutinating (HA) and chick cell agglutinating (CCA) techniques and both measure the same biological activity. With the establis…
View article: International collaborative studies on the pertussis vaccine potency assay. Part played by the challenge in the mouse-protection test.
International collaborative studies on the pertussis vaccine potency assay. Part played by the challenge in the mouse-protection test. Open
Because of wide variations in the methods used to assay the potency of pertussis vaccine, the effect of the type of challenge used in the mouse-protection test was studied. Eight laboratories took part in a collaborative investigation and …
View article: Vaccination against whooping-cough.
Vaccination against whooping-cough. Open
on which any further analysis is made.Further reports from the P.H.L.
View article: Variation of killing power of human sera against Bordetella pertussis.
Variation of killing power of human sera against Bordetella pertussis. Open
A direct serological test has been developed, the effects of which have been shown, by electron microscopy, to be produced by immune lysis. The antibodies measured by the test show some measure of strain specificity, though this does not s…
View article: Antibody response and reactions to aqueous influenza vaccine, simple emulsion vaccine and multiple emulsion vaccine. A report to the Medical Research Council Committee on influenza and other respiratory virus vaccines
Antibody response and reactions to aqueous influenza vaccine, simple emulsion vaccine and multiple emulsion vaccine. A report to the Medical Research Council Committee on influenza and other respiratory virus vaccines Open
Influenza vaccines prepared with a mineral oil adjuvant induce a substantial and durable antibody response. However, vaccines containing mineral oil in simple emulsion (water-in-oil emulsion) sometimes produce persistent local reactions (M…
View article: Precautions Against B Virus Infection
Precautions Against B Virus Infection Open
ResultsOf the 303 patients 38 (6 male, 32 female) had no apparent, cause for an abnormal E.S.R., and a further 33 (4 male, 29 female) no apparent cause apart from an occult infection of the urinary tract (in only 4 of these latter 33 patie…
View article: FIFTH INTERNATIONAL STANDARD FOR GAS-GANGRENE ANTITOXIN (PERFRINGENS) (CLOSTRIDIUM WELCHII TYPE A ANTITOXIN).
FIFTH INTERNATIONAL STANDARD FOR GAS-GANGRENE ANTITOXIN (PERFRINGENS) (CLOSTRIDIUM WELCHII TYPE A ANTITOXIN). Open
The Fifth International Standard Gas-Gangrene Antitoxin (Perfringens) (Clostridium welchii Type A Antitoxin) was prepared from serum from immunized horses. It was freeze-dried in ampoules each containing 1 ml. Seven laboratories collaborat…
View article: Effect of a Single Dose of Oral Poliovirus Vaccine in Persons Previously Immunized with Inactivated Vaccine
Effect of a Single Dose of Oral Poliovirus Vaccine in Persons Previously Immunized with Inactivated Vaccine Open
ORAL POLIOMYELITIS VACCINESMEDIALTHNAL 145 a fourth dose of Salk vaccine.Unfortunately this was impracticable.However, the antibody response obtained seemed to be of much the same order as that to a fourth dose of Salk vaccine recorded by …
View article: An international collaborative study of the assay of the potency of poliomyelitis sera.
An international collaborative study of the assay of the potency of poliomyelitis sera. Open
As a first step towards the standardization of poliomyelitis vaccine, the neutralizing antibody titres of ten test antipoliomyelitis sera were measured in nine laboratories in different countries in comparison with a reference preparation.…
View article: Responses of 6- and 9-months-old Infants to Two and Three Doses of Poliomyelitis Vaccine
Responses of 6- and 9-months-old Infants to Two and Three Doses of Poliomyelitis Vaccine Open
MEDICALJOURNALdeoxycortone acetate used in this work during the past four years, and Boots Pure Drug Co. for donations of cortisone and heparin.We are much indebted to the members of our Unit-Messrs.J. Coghlan, B.Sc., J. Blair-West, B. Dyz…