Edmar Zanotelli YOU? Author Swipe

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Muscle Biopsy Findings in Valosin-Containing Protein Multisystem Proteinopathy Open

Marianela Schiava, Yolande Parkhurst, Matthew Henderson, Tuomo Polvikoski, Manouela V. Valtcheva , et al. · 2025

VCP-MSP muscle biopsies consistently show myopathic or mixed patterns with rimmed vacuoles and p62/VCP-positive inclusions, regardless of clinical phenotype, age, or progression. Some lack vacuoles, challenging diagnosis. Discrepancies bet…