Explanipedia

Dynamic proton arc treatment planning study for oesophageal cancer Open

Macarena Chocan Vera, Anne-Catherine Wéra, Hamdiye Ozan, Erik Engwall, Viktor Wase , et al. · 2025

Particle Arc Therapy (PAT) is considered a promising technique to improve conformity and reduce toxicities. Robustly optimized PAT plans were evaluated versus Intensity Modulated Proton Therapy (IMPT) for oesophageal cancer in 17 patients.…

Towards faster plan adaptation for proton arc therapy using initial treatment plan information Open

Benjamin Roberfroid, Margerie Huet Dastarac, Elena Borderías Villarroel, Rodin Koffeing, John A. Lee , et al. · 2025

Smart-adapted plans achieve similar plan quality to the reference method, while significantly reducing plan generation time for new patient anatomy.

Robustness Evaluation in proton therapy: An ESTRO Delphi consensus Open

Francesco Fracchiolla, Artūrs Meijers, Ester Orlandi, Erik W. Korevaar, Gillian Whitfield , et al. · 2025

Potential of automated online adaptive proton therapy to reduce margins for oesophageal cancer Open

Pascal Herbst, Camille Draguet, Ana María Barragán Montero, Elena Borderias‐Villarroel, Macarena Chocan Vera , et al. · 2025

Treatment Planning Study for Oesophageal Cancer: Dynamic Proton Arc vs Conventional Intensity Modulated Proton Therapy Open

Macarena S. Chocan, Anne-Catherine Wéra, Hamdiye Ozan, S. Wuyckens, Erik Engwall , et al. · 2025

A dosimetric and robustness analysis of proton arc therapy with early energy layer and spot assignment for lung cancer versus conventional intensity modulated proton therapy Open

Macarena S. Chocan, S. Wuyckens, Damien Dasnoy, Dario Di Perri, Elena Borderias‐Villarroel , et al. · 2024

Background and purpose: Intensity Modulated Proton Therapy (IMPT) faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proton Arc Therapy (PAT) is…

A comparative study on automatic treatment planning for online adaptive proton therapy of esophageal cancer: which combination of deformable registration and deep learning planning tools performs the best? Open

Camille Draguet, Pieter Populaire, Macarena Chocan Vera, Albin Fredriksson, Karin Haustermans , et al. · 2024

Objective. To demonstrate the feasibility of integrating fully-automated online adaptive proton therapy strategies (OAPT) within a commercially available treatment planning system and underscore what limits their clinical implementation. T…

A dosimetric and robustness analysis of Proton Arc Therapy (PAT) with Early Energy Layer and Spot Assignment (ELSA) for lung cancer versus conventional Intensity modulated therapy (IMPT) Open

Macarena S. Chocan, S. Wuyckens, Damien Dasnoy, Dario Di Perri, Elena Borderias Villarruel , et al. · 2024

Background and purpose: IMPT faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proton Arc Therapy (PAT) is an alternative to maintain target co…

Phase-change ultrasound contrast agents for proton range verification: towards an in vivo application Open

Bram Carlier, Sophie V. Heymans, Gonzalo Collado‐Lara, Luigi Musetta, Marcus Ingram , et al. · 2024

Objective. In proton therapy, range uncertainties prevent optimal benefit from the superior depth-dose characteristics of proton beams over conventional photon-based radiotherapy. To reduce these uncertainties we recently proposed the use …

Autodelineation methods in a simulated fully automated proton therapy workflow for esophageal cancer Open

Pieter Populaire, Beatrice Marini, Kenneth Poels, Stina Svensson, Edmond Sterpin , et al. · 2024

Monte Carlo simulation of initial and volume ion recombination correction factor in plane parallel ionization chambers exposed to ion beams Open

Marina Orts, Séverine Rossomme, Kevin Souris, Edmond Sterpin · 2024

Objective. Accurate reference dosimetry with ionization chambers (ICs) relies on correcting for various influencing factors, including ion recombination. Theoretical frameworks, such as the Boag and Jaffe theories, are conventionally used …

Time is NTCP: Should we maximize patient throughput or perform online adaptation on proton therapy systems? Open

Elena Borderias‐Villarroel, Ana María Barragán Montero, Edmond Sterpin · 2024

PROTON FLASH IRRADIATION SPARES ZEBRAFISH EMBRYOS FROM RADIATION-INDUCED DNA DAMAGE AND RESULTS IN REDUCED LEVELS OF APOPTOSIS AND INFLAMMATION Open

Eva Bogaerts, Ellina Macaeva, Gaëlle Saade, Sophie Chiavassa, Charbel Koumeir , et al. · 2024

TOWARDS FAST PLAN ADAPTATION FOR PROTON ARC THERAPY Open

Benjamin Roberfroid, Ana María Barragán Montero, John A. Lee, Edmond Sterpin · 2024

PARROT: A USER-FRIENDLY WEB PLATFORM FOR AI-DRIVEN RADIATION THERAPY PLANNING Open

Margerie Huet Dastarac, Wei Zhao, Ana María Barragán Montero, Sylvain Deffet, E. Longton , et al. · 2024

Robustness evaluation of pencil beam scanning proton therapy treatment planning: A systematic review Open

Edmond Sterpin, L. Widesott, Kenneth Poels, Mischa S. Hoogeman, Erik W. Korevaar , et al. · 2024

ADAPTIVE RADIOTHERAPY FOR ESOPHAGEAL CANCER PATIENTS: ADAPTATION RATES AND BENEFITS Open

Camille Draguet, Pieter Populaire, Macarena Chocan Vera, Karin Haustermans, John A. Lee , et al. · 2024

NEW CORRECTION FACTOR FOR IONIZATION CHAMBERS EXPOSED TO ULTRA-HIGH DOSE RATE PER PULSE PROTON BEAMS Open

Marina Orts Sanz, Séverine Rossomme, Kevin Souris, Jarrick Nys, Edmond Sterpin · 2024

ENERGY LAYER PRE-SELECTION FOR PROTON ARC THERAPY: BALANCING DELIVERY TIME AND GEOMETRICAL COVERAGE Open

S. Wuyckens, Guillaume Janssens, Macarena Chocan Vera, Dario Di Perri, Edmond Sterpin , et al. · 2024

A Preliminary Investigation of Radiation-Sensitive Ultrasound Contrast Agents for Photon Dosimetry Open

Bram Carlier, Sophie V. Heymans, Sjoerd Nooijens, Gonzalo Collado‐Lara, Yosra Toumia , et al. · 2024

Radiotherapy treatment plans have become highly conformal, posing additional constraints on the accuracy of treatment delivery. Here, we explore the use of radiation-sensitive ultrasound contrast agents (superheated phase-change nanodrople…

Efficient proton arc optimization and delivery through energy layer pre‐selection and post‐filtering Open

S. Wuyckens, Viktor Wase, Otte Marthin, Johan Sundström, Guillaume Janssens , et al. · 2024

Background Proton arc therapy (PAT) has emerged as a promising approach for improving dose distribution, but also enabling simpler and faster treatment delivery in comparison to conventional proton treatments. However, the delivery speed a…

Evaluation of safety margins for cone beam CT-based adaptive prostate radiotherapy Open

Florian Dupont, David Dechambre, Edmond Sterpin · 2024

Balancing robustness and adaptation rate for proton therapy of lung cancer patients Open

Vlad Badiu, Vicki Trier Taasti, Gilles Defraene, Wouter van Elmpt, Edmond Sterpin · 2024

Markerless liver online adaptive stereotactic radiotherapy: feasibility analysis Open

Julien Pierrard, S. Deheneffe, David Dechambre, Edmond Sterpin, Xavier Geets , et al. · 2024

Objective . Radio-opaque markers are recommended for image-guided radiotherapy in liver stereotactic ablative radiotherapy (SABR), but their implantation is invasive. We evaluate in this in-silico study the feasibility of cone-beam compute…

DIVE-ART: A tool to guide clinicians towards dosimetrically informed volume editions of automatically segmented volumes in adaptive radiation therapy Open

Benjamin Roberfroid, John A. Lee, Xavier Geets, Edmond Sterpin, Ana María Barragán Montero · 2024

Fast Plan Adaptation for Proton Arc Therapy Using Initial Treatment Plan Information Open

Benjamin Roberfroid, Margerie Huet Dastarac, Elena Borderias‐Villarroel, Rodin Koffeing, John A. Lee , et al. · 2024

Comparison of Ethos template-based planning and AI-based dose prediction: General performance, patient optimality, and limitations Open

Benjamin Roberfroid, Ana María Barragán Montero, David Dechambre, Edmond Sterpin, John A. Lee , et al. · 2023

Technical note: Beamlet‐free optimization for Monte‐Carlo‐based treatment planning in proton therapy Open

Danah Pross, S. Wuyckens, Sylvain Deffet, Edmond Sterpin, John A. Lee , et al. · 2023

Background Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder the implementation of efficient workflows in clinics and pre…

Efficient proton arc optimization and delivery through energy layer pre-selection and post-filtering Open

S. Wuyckens, V. Wase, O. Marthin, Johan Sundström, Guillaume Janssens , et al. · 2023

Proton arc therapy (PAT) has emerged as a promising approach for improving dose distribution, but also enabling simpler and faster treatment delivery in comparison to conventional proton treatments. However, the delivery speed achievable i…

A spot‐specific range uncertainty framework for robust optimization of proton therapy treatments Open

Marie Cohilis, Kevin Souris, Gregory Buti, Chih‐Wei Chang, Liyong Lin , et al. · 2023

Purpose An accurate estimation of range uncertainties is essential to exploit the potential of proton therapy. According to Paganetti's study, a value of 2.4% (1.5 standard deviation) is currently recommended for planning robust treatments…

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