Mariana Tinoco
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View article: Transcatheter edge-to-edge mitral valve repair <i>versus</i> medical therapy for secondary mitral regurgitation: a meta-analysis of randomized controlled trials
Transcatheter edge-to-edge mitral valve repair <i>versus</i> medical therapy for secondary mitral regurgitation: a meta-analysis of randomized controlled trials Open
Secondary mitral regurgitation (SMR) is associated with increased hospitalizations and mortality. Clinical trials comparing mitral valve transcatheter edge-to-edge repair (M-TEER) with guideline-directed medical therapy (GDMT) show conflic…
View article: Ghostly intrusion on a frightful Halloween night: a case report of dual valve endocarditis
Ghostly intrusion on a frightful Halloween night: a case report of dual valve endocarditis Open
Multivalvular endocarditis (MVE) is an uncommon presentation and mostly involves mitral and aortic valves. Here, we present a case of an MVE with an unusual and bizarre presentation on a Halloween night with a massive degree of valve destr…
View article: Differential diagnosis of hypertrophic cardiomyopathy, fabry cardiomyopathy and transthyretin cardiac amyloidosis: insights from right ventricular strain imaging echocardiography
Differential diagnosis of hypertrophic cardiomyopathy, fabry cardiomyopathy and transthyretin cardiac amyloidosis: insights from right ventricular strain imaging echocardiography Open
Introduction Timely differential diagnosis between hypertrophic cardiomyopathy (HCM), Fabry cardiomyopathy (FC) and wild-type transthyretin cardiac amyloidosis (ATTR-CA) is crucial for appropriate treatment and family screening. Right vent…
View article: Short- and long-term outcomes of percutaneous left atrial appendage occlusion in cancer patients
Short- and long-term outcomes of percutaneous left atrial appendage occlusion in cancer patients Open
LAAO procedure was safe and effective in both populations. Cancer patients experienced higher rates of all-cause mortality, with no differences in stroke and bleeding outcomes between groups.
View article: “Hot phase” clinical presentation of biventricular arrhythmogenic cardiomyopathy: when the perfect electrical storm spontaneously stops
“Hot phase” clinical presentation of biventricular arrhythmogenic cardiomyopathy: when the perfect electrical storm spontaneously stops Open
An 18-year-old male presented with syncope during a training break. Post-syncope, he developed effort dyspnea, which he associated with the Pfizer-BioNTech COVID-19 vaccine received a week earlier. Electrocardiogram showed T inversion in V…
View article: Environmental impact analysis of ajmaline challenge protocols: a comparative assessment of carbon footprint reduction in Brugada Syndrome diagnosis
Environmental impact analysis of ajmaline challenge protocols: a comparative assessment of carbon footprint reduction in Brugada Syndrome diagnosis Open
Background Climate change is an urgent public health crisis that significantly impacts disease development and health outcomes. The 2022 Lancet Countdown Report revealed that healthcare contributes with 5.2% of global emissions, prompting …
View article: Remote monitoring of cardiac implantable electronic devices to predict acute clinical decompensation events
Remote monitoring of cardiac implantable electronic devices to predict acute clinical decompensation events Open
Background Heart failure (HF) patients are at constant risk of decompensation, and urgent hospital admissions can be life‐threatening events. Monitoring biological variables has been proved to be an important mechanism to anticipate decomp…
View article: Assessing cardiac resynchronization therapy response in heart failure patients: a comparative analysis of efficacy and outcomes between transvenous and epicardial leads
Assessing cardiac resynchronization therapy response in heart failure patients: a comparative analysis of efficacy and outcomes between transvenous and epicardial leads Open
Cardiac resynchronization therapy (CRT) is an effective treatment for selected heart failure (HF) patients. Although transvenous implantation is the standard method, it is not feasible in some patients, so the epicardial lead emerges as an…
View article: Fulminant Necrotizing Eosinophilic Myocarditis Successfully Treated With Veno-Arterial Extracorporeal Membrane Oxygenation and High-Dose Steroids
Fulminant Necrotizing Eosinophilic Myocarditis Successfully Treated With Veno-Arterial Extracorporeal Membrane Oxygenation and High-Dose Steroids Open
Fulminant necrotizing eosinophilic myocarditis (FNEM) is a rare form of EM characterized by biventricular heart failure with hemodynamic deterioration, often requiring inotropes or mechanical circulatory support. Here, we report a case of …
View article: The unmasking of a massive pericardial effusion: a rare and unlucky outcome
The unmasking of a massive pericardial effusion: a rare and unlucky outcome Open
The unmasking of a massive pericardial effusion: a rare and unlucky outcome
View article: Prognostic value of exercise stress echocardiography in patients with known coronary artery disease
Prognostic value of exercise stress echocardiography in patients with known coronary artery disease Open
Funding Acknowledgements Type of funding sources: None. Background Exercise stress echocardiography (EE) is useful for diagnosis and risk stratification in patients (pts) with suspected coronary artery disease (CAD). Pts with known CAD car…
View article: Left ventricular diastolic function in patients with breast cancer under chemotherapy
Left ventricular diastolic function in patients with breast cancer under chemotherapy Open
Funding Acknowledgements Type of funding sources: None. Background Chemotherapy, in particular anthracyclines (A) and trastuzumab (T), have improved disease-free survival and overall prognosis in patients with breast cancer (BC). The use o…
View article: Predictors of major adverse cardiovascular events in patients with heart failure with reduced ejection fraction
Predictors of major adverse cardiovascular events in patients with heart failure with reduced ejection fraction Open
Funding Acknowledgements Type of funding sources: None. Background Heart failure (HF) is a growing epidemic, currently affecting more than 26 million people around the globe. Outcomes of patients with HF with reduced ejection fraction (HFr…
View article: Impact of recurrent acute heart failure hospitalizations on prognosis of heart failure patients
Impact of recurrent acute heart failure hospitalizations on prognosis of heart failure patients Open
Funding Acknowledgements Type of funding sources: None. Introduction Hospitalizations for acute heart failure (AHF) are significant events for heart failure (HF) patients (pts) with each hospitalization portending a poor prognosis. Our aim…
View article: Comparison of major adverse cardiovascular events between sacubitril-valsartan versus ACEI/ARB therapy in patients with heart failure with reduced ejection fraction
Comparison of major adverse cardiovascular events between sacubitril-valsartan versus ACEI/ARB therapy in patients with heart failure with reduced ejection fraction Open
Funding Acknowledgements Type of funding sources: None. Background Sacubitril-valsartan (S-V) reduced risks of Major Adverse Cardiovascular Events (MACE) for heart failure (HF) versus enalapril in ambulatory patients with HF and reduced ej…
View article: Cancer therapeutics-related cardiac dysfunction: what is the role of cardioprotective medication?
Cancer therapeutics-related cardiac dysfunction: what is the role of cardioprotective medication? Open
Funding Acknowledgements Type of funding sources: None. Introduction Cancer therapy-related cardiac dysfunction (CTRCD) is one of the major complications being reported in patients with breast cancer (BC) under chemotherapy, in particular …
View article: A left systolic dysfunction study in a group of breast cancer patients and its clinical impact
A left systolic dysfunction study in a group of breast cancer patients and its clinical impact Open
Funding Acknowledgements Type of funding sources: None. Background Cancer therapy-related cardiac dysfunction (CTRCD) is one of the major complications being reported in patients with breast cancer (BC) under chemotherapy, in particular wi…
View article: Impact of an inconclusive exercise stress echocardiogram on cardiovascular outcomes
Impact of an inconclusive exercise stress echocardiogram on cardiovascular outcomes Open
Funding Acknowledgements Type of funding sources: None. Background Exercise stress echocardiography (ESE) is used for the assessment of suspected or known coronary artery disease (CAD); however, a certain percentage of ESE studies are inco…
View article: Characterization of temporal trends of systolic and diastolic indexes over time in breast cancer patients treated with trastuzumab
Characterization of temporal trends of systolic and diastolic indexes over time in breast cancer patients treated with trastuzumab Open
Funding Acknowledgements Type of funding sources: None. Background Trastuzumab therapy increases survival in patients (pts) with HER2 positive breast cancer, however, it is associated with a risk of cardiotoxicity (CT). Our aim was to: 1) …
View article: Association between cardiovascular risk factors and cancer therapy-related cardiac dysfunction in patients with breast cancer
Association between cardiovascular risk factors and cancer therapy-related cardiac dysfunction in patients with breast cancer Open
Funding Acknowledgements Type of funding sources: None. Background Cancer therapy-related cardiac dysfunction (CTRCD) is one of the major complications being reported in breast cancer (BC) patients. The clinical relevance of CTRCD and its …
View article: Prevalence and clinical impact of latent obstruction in hypertrophic cardiomyopathy
Prevalence and clinical impact of latent obstruction in hypertrophic cardiomyopathy Open
Funding Acknowledgements Type of funding sources: None. BACKGROUND Hypertrophic cardiomyopathy (HCM) is characterized by varying degrees of left ventricular outflow tract obstruction (LVOTobs). We aim to define the prevalence, clinical pro…
View article: Electrophysiologic study for risk stratification in Brugada Syndrome: does it still matters?
Electrophysiologic study for risk stratification in Brugada Syndrome: does it still matters? Open
Background The value of eletrophisiologic study (EPS) with programmed ventricular stimulation for risk stratification in patients with Brugada Syndrome (BS) remains controversial. Purpose The aim of this study is to determine the clinical …
View article: Right ventricular dysfunction is a predictor of non-response to cardiac resynchronization therapy
Right ventricular dysfunction is a predictor of non-response to cardiac resynchronization therapy Open
Introduction Cardiac resynchronization therapy (CRT) has been of great benefit to many heart failure (HF) patients with reduced ejection fraction (EF) and intraventricular conduction delay. However, approximately 30% of patients fail to re…
View article: Massive myocardial calcification: a heart of stone!
Massive myocardial calcification: a heart of stone! Open
A 71-year-old female was admitted in the emergency room after effort-related syncope. She had past medical history of obesity and hypertension treated with lercanidipine. No relevant family history. Physical examination revealed systolic m…
View article: Perimyocarditis Following COVID-19 Vaccination
Perimyocarditis Following COVID-19 Vaccination Open
A 39-year-old male was admitted in the emergency room with chest pain. He had been given the second dose of Pfizer–BioNTech COVID-19 vaccine 3 days before. The patient denied taking any other medication beyond the usual. He didn’t feel sic…