Eduardo Henrique de Lima Umeoka
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View article: Stress: Influences and Determinants of Psychopathology
Stress: Influences and Determinants of Psychopathology Open
The stress response is a natural physiological reaction of the organism, elicited to maintain the internal environment and evoke adaptive behaviors, ultimately leading to survival. However, at the turn of the century, stress-related disord…
View article: Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation
Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation Open
View article: Evaluation of the HPA Axis’ Response to Pharmacological Challenges in Experimental and Clinical Early-Life Stress-Associated Depression
Evaluation of the HPA Axis’ Response to Pharmacological Challenges in Experimental and Clinical Early-Life Stress-Associated Depression Open
Early-life stress (ELS) is associated with a higher risk of psychopathologies in adulthood, such as depression, which may be related to persistent changes in the hypothalamic-pituitary-adrenal (HPA) axis. This study aimed to evaluate the e…
View article: Evaluation of Maternal Reproductive Outcomes and Biochemical Analysis from Wistar Audiogenic Rats (WAR) and Repercussions in Their Offspring
Evaluation of Maternal Reproductive Outcomes and Biochemical Analysis from Wistar Audiogenic Rats (WAR) and Repercussions in Their Offspring Open
View article: The Role of Stress in Bipolar Disorder
The Role of Stress in Bipolar Disorder Open
View article: Hyperthermia‐induced seizures followed by repetitive stress are associated with age‐dependent changes in specific aspects of the mouse stress system
Hyperthermia‐induced seizures followed by repetitive stress are associated with age‐dependent changes in specific aspects of the mouse stress system Open
Stress is among the most frequently self‐reported factors provoking epileptic seizures in children and adults. It is still unclear, however, why some people display stress‐sensitive seizures and others do not. Recently, we showed that youn…
View article: A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications
A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications Open
Stress is recognized as an important issue in basic and clinical neuroscience research, based upon the founding historical studies by Walter Canon and Hans Selye in the past century, when the concept of stress emerged in a biological and a…
View article: Maternal reproductive performance and fetal development of the Wistar Audiogenic Rat (WAR) strain
Maternal reproductive performance and fetal development of the Wistar Audiogenic Rat (WAR) strain Open
Wistar Audiogenic Rat (WAR) strain is an animal model for epilepsy studies, the chronic multifactorial disease that affects millions of people worldwide. The animals of this strain are genetically predisposed to sound-induced seizures, cal…
View article: Multimodal early-life stress induces biological changes associated to psychopathologies
Multimodal early-life stress induces biological changes associated to psychopathologies Open
View article: Stress and Corticosteroids Aggravate Morphological Changes in the Dentate Gyrus after Early-Life Experimental Febrile Seizures in Mice
Stress and Corticosteroids Aggravate Morphological Changes in the Dentate Gyrus after Early-Life Experimental Febrile Seizures in Mice Open
Stress is the most frequently self-reported seizure precipitant in patients with epilepsy. Moreover, a relation between ear stress and epilepsy has been suggested. Although ear stress and stress hormones are known to influence seizure thre…
View article: Intense olfactory stimulation blocks seizures in an experimental model of epilepsy
Intense olfactory stimulation blocks seizures in an experimental model of epilepsy Open
View article: Oxidative stress and Na,K-ATPase activity differential regulation in brainstem and forebrain of Wistar Audiogenic rats may lead to increased seizure susceptibility
Oxidative stress and Na,K-ATPase activity differential regulation in brainstem and forebrain of Wistar Audiogenic rats may lead to increased seizure susceptibility Open
View article: The Wistar Audiogenic Rat (WAR) strain and its contributions to epileptology and related comorbidities: History and perspectives
The Wistar Audiogenic Rat (WAR) strain and its contributions to epileptology and related comorbidities: History and perspectives Open