Pedro F. Costa
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View article: FORMAÇÃO DE PROFESSORES: O PILAR FUNDAMENTAL PARA UMA EDUCAÇÃO DE QUALIDADE
FORMAÇÃO DE PROFESSORES: O PILAR FUNDAMENTAL PARA UMA EDUCAÇÃO DE QUALIDADE Open
A pesquisa examinou como a formação docente sustenta a qualidade do ensino, partindo da necessidade de compreender por que determinados ambientes educativos alcançam resultados mais consistentes que outros. O estudo teve como objetivo anal…
View article: População carcerária feminina e os desafios da ressocialização no Brasil
População carcerária feminina e os desafios da ressocialização no Brasil Open
The female prison population in Brazil has increased in recent decades, highlighting the weaknesses of the penitentiary system and the challenges of rehabilitation. Marked by overcrowding, poor infrastructure, and the lack of effective rei…
View article: INTELIGÊNCIA ARTIFICIAL E EDUCAÇÃO: TECNOLOGIA COMO ALIADA, PROFESSOR COMO AUTOR PROTAGONISTA
INTELIGÊNCIA ARTIFICIAL E EDUCAÇÃO: TECNOLOGIA COMO ALIADA, PROFESSOR COMO AUTOR PROTAGONISTA Open
Este estudo analisa a integração da Inteligência Artificial (IA) na educação, considerando como problema central a tendência da produção acadêmica em privilegiar aspectos técnicos das ferramentas digitais em detrimento da ênfase no protago…
View article: Electrospun Poly(L-lactide-co-ε-caprolactone) Nanofibers with Hydroxyapatite Nanoparticles Mimic Cellular Interplay in Bone Regeneration
Electrospun Poly(L-lactide-co-ε-caprolactone) Nanofibers with Hydroxyapatite Nanoparticles Mimic Cellular Interplay in Bone Regeneration Open
This study investigates the impact of hydroxyapatite (HA) nanoparticles (NPs) on the cellular responses of poly(L-lactide-co-ε-caprolactone) (PLCL) scaffolds in bone tissue engineering applications. Three types of PLCL scaffolds were fabri…
View article: ABDOME AGUDO EM GESTAÇÃO HETEROTÓPICA: DESAFIOS DIAGNÓSTICOS E OPÇÕES TERAPÊUTICAS
ABDOME AGUDO EM GESTAÇÃO HETEROTÓPICA: DESAFIOS DIAGNÓSTICOS E OPÇÕES TERAPÊUTICAS Open
A gestação heterotópica, definida pela coexistência de uma gestação intrauterina viável e uma ectópica, é uma condição rara e de alta gravidade, cuja incidência tem aumentado com o uso das técnicas de reprodução assistida (TRA). Este estud…
View article: Advancing organ-on-chip systems: the role of microfluidics in neuro-cardiac research
Advancing organ-on-chip systems: the role of microfluidics in neuro-cardiac research Open
View article: Caldyn: An Advanced High-Throughput Automated Algorithm for Monitoring Intracellular Ca2+ Dynamics and Electrophysiological Signals in Patient-Derived Cells
Caldyn: An Advanced High-Throughput Automated Algorithm for Monitoring Intracellular Ca2+ Dynamics and Electrophysiological Signals in Patient-Derived Cells Open
View article: AVANÇOS NA GESTÃO DE RADICULOPATIAS: O PAPEL DAS TÉCNICAS MINIMAMENTE INVASIVAS
AVANÇOS NA GESTÃO DE RADICULOPATIAS: O PAPEL DAS TÉCNICAS MINIMAMENTE INVASIVAS Open
As radiculopatias, caracterizadas por compressão ou irritação das raízes nervosas espinhais, representam uma causa significativa de dor e incapacidade funcional em populações de diferentes faixas etárias. Tradicionalmente, o manejo dessas …
View article: Créditos de Descarbonização (CBIOs)
Créditos de Descarbonização (CBIOs) Open
O artigo trata da análise normativa dos Créditos de Descarbonização (CBIOs) no Brasil, discorrendo sobre sua natureza jurídica, analisando a tipologia de sua negociação no mercado e descrevendo o regime tributário de tais operações. A anál…
View article: The Current State of Realistic Heart Models for Disease Modelling and Cardiotoxicity
The Current State of Realistic Heart Models for Disease Modelling and Cardiotoxicity Open
One of the many unresolved obstacles in the field of cardiovascular research is an uncompromising in vitro cardiac model. While primary cell sources from animal models offer both advantages and disadvantages, efforts over the past half-cen…
View article: Increasing hydrogel complexity from 2D towards 3D towards intestinal tissue engineering
Increasing hydrogel complexity from 2D towards 3D towards intestinal tissue engineering Open
There is a high demand for in vitro intestinal models towards studying intestinal disfunctions, such as gastrointestinal diseases (Crohn's disease, irritable bowel syndrome, colorectal cancer, etc.) which are commonly diagnosed in modern s…
View article: Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes
Multifactorial approaches to enhance maturation of human iPSC-derived cardiomyocytes Open
View article: Light‐Based 3D Printing of Gelatin‐Based Biomaterial Inks to Create a Physiologically Relevant In Vitro Fish Intestinal Model
Light‐Based 3D Printing of Gelatin‐Based Biomaterial Inks to Create a Physiologically Relevant In Vitro Fish Intestinal Model Open
To provide prominent accessibility of fishmeal to the European population, the currently available, time‐ and cost‐extensive feeding trials, which evaluate fish feed, should be replaced. The current paper reports on the development of a no…
View article: Electrosprayed Particles Loaded with Kartogenin as a Potential Osteochondral Repair Implant
Electrosprayed Particles Loaded with Kartogenin as a Potential Osteochondral Repair Implant Open
The restoration of cartilage damage is a slow and not always successful process. Kartogenin (KGN) has significant potential in this space—it is able to induce the chondrogenic differentiation of stem cells and protect articular chondrocyte…
View article: Potential of Electrospun Fibrous Scaffolds for Intestinal, Skin, and Lung Epithelial Tissue Modeling
Potential of Electrospun Fibrous Scaffolds for Intestinal, Skin, and Lung Epithelial Tissue Modeling Open
Herein, intestinal, skin, and pulmonary in vitro tissue models based on electrospun membranes of poly(ε‐caprolactone) (PCL) and cellulose acetate (CA), cellulose acetate phthalate (CAP), ethylcellulose (EC), or methylcellulose (MC) are pre…
View article: A comprehensive overview of advanced dynamic <i>in vitro</i> intestinal and hepatic cell culture models
A comprehensive overview of advanced dynamic <i>in vitro</i> intestinal and hepatic cell culture models Open
Orally administered drugs pass through the gastrointestinal tract before being absorbed in the small intestine and metabolised in the liver. To test the efficacy and toxicity of drugs, animal models are often employed; however, they are no…
View article: Optimal microstructure and mechanical properties of open-cell porous titanium structures produced by selective laser melting
Optimal microstructure and mechanical properties of open-cell porous titanium structures produced by selective laser melting Open
Three-dimensional printing technology enables the production of open cell porous structures. This has advantages but not only in terms of weight reduction. In implant structures, the process of osseointegration is improved, mechanical inte…
View article: Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells (Adv. Biology 2/2022)
Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells (Adv. Biology 2/2022) Open
Artificial Lung Models In article 2101139, Costa and co-workers use of biomanufacturing (electrospinning/3D-printing) and lung-on-chip technology for the development of artificial lung models. As such, microfluidic channels and 3D-printed …
View article: Optimal Microstructure and Mechanical Properties of Open-Cell Porous Titanium Structures Produced by Selective Laser Melting
Optimal Microstructure and Mechanical Properties of Open-Cell Porous Titanium Structures Produced by Selective Laser Melting Open
View article: Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells
Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells Open
The substantial socioeconomic burden of lung diseases, recently highlighted by the disastrous impact of the coronavirus disease 2019 (COVID‐19) pandemic, accentuates the need for interventive treatments capable of decelerating disease prog…
View article: Organ-on-Chip Approaches for Intestinal 3D In Vitro Modeling
Organ-on-Chip Approaches for Intestinal 3D In Vitro Modeling Open
The intestinal epithelium has one of the highest turnover rates in the human body, which is supported by intestinal stem cells. Culture models of intestinal physiology have been evolving to incorporate different tissue and microenvironment…
View article: Osteochondral Tissue Engineering: The Potential of Electrospinning and Additive Manufacturing
Osteochondral Tissue Engineering: The Potential of Electrospinning and Additive Manufacturing Open
The socioeconomic impact of osteochondral (OC) damage has been increasing steadily over time in the global population, and the promise of tissue engineering in generating biomimetic tissues replicating the physiological OC environment and …
View article: An investigation of alkaline phosphatase enzymatic activity after electrospinning and electrospraying
An investigation of alkaline phosphatase enzymatic activity after electrospinning and electrospraying Open
View article: Digitally Assisted Versus Conventional Home-Based Rehabilitation After Arthroscopic Rotator Cuff Repair
Digitally Assisted Versus Conventional Home-Based Rehabilitation After Arthroscopic Rotator Cuff Repair Open
Objective The aim of this study was to evaluate the clinical impact of a 12-wk home-based digitally assisted rehabilitation program after arthroscopic rotator cuff repair against conventional home-based rehabilitation. Design The digital t…
View article: Iron triggers the early stages of cartilage degeneration in vitro: The role of articular chondrocytes
Iron triggers the early stages of cartilage degeneration in vitro: The role of articular chondrocytes Open
View article: In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review
In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review Open
Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. Over the years, these cardiovascular complications have been extensively studied by applying in vivo , in …
View article: Protein encapsulation by electrospinning and electrospraying
Protein encapsulation by electrospinning and electrospraying Open
View article: Integration and Vascular Ingrowth of a Collagen Meniscal Implant: A Case Report
Integration and Vascular Ingrowth of a Collagen Meniscal Implant: A Case Report Open
Meniscectomy is the most common surgery in orthopaedics. The absence of meniscal tissue might be related to irreversible damage to the articular cartilage. Meniscal replacement is a tissue-engineering technique for post-meniscectomy syndro…
View article: Experimental and Simulation Results of "Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation"
Experimental and Simulation Results of "Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation" Open
This repository contains the experimental and simulation results of the submitted article "Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation" by Carvalho, V., Rodrigues, N., R…
View article: Data related to Mechanical characterization of gel-based vessel-like structures contained within fluidic devices
Data related to Mechanical characterization of gel-based vessel-like structures contained within fluidic devices Open
This repository contains the experimental results related to mechanical characterization of gel-based vessel-like structures contained within fluidic devices.