Edurne Gorraitz
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View article: Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1
Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1 Open
Significance Site-directed fluorometry was used to understand conformational changes of the Na + /glucose symporter. SGLT1 functions by a mechanism where the substrate-binding site alternates between the two faces of the membrane, but litt…
View article: Structural and functional significance of water permeation through cotransporters
Structural and functional significance of water permeation through cotransporters Open
Significance Transport of water and polar solutes across membranes play an important physiological role, and it is widely appreciated that many membrane transport proteins are permeable to water. Molecular dynamics studies of sodium-couple…