Explanipedia

A-414 Assessment of the DCA Vantage and Atellica DCA HbA1c Dx Assays Compared to the European Reference Laboratory Method Open

Chad Yost, Hildebert Wagner, Nicole Ellis, Aaron Kauffmann, J. A. Wilson , et al. · 2025

Background Measurement of HbA1c point-of-care testing (POCT) provides rapid test results during patient/doctor office visits. This added convenience also has potential for broader reach to low-access populations. The European Reference Lab…

Pregnancy Outcomes in Women with Low and Ultra-Low Ejection Fraction: A Retrospective Study in a Tertiary Care Center Open

Bashayer Saeed, Amani Albalawi, Marwah Bintalib, Amjad Alturki, Edward Devol , et al. · 2025

The data about pregnancy while having a low ejection fraction are scarce, since pregnancy is not recommended for women with an ejection fraction of less than 30%. There is an increased risk of obstetrical complications and adverse maternal…

Challenges and barriers toward conducting research at a tertiary hospital in Saudi Arabia Open

Amani Almeharish, Gamal Mohamed, Edward Devol, Elaf Almuaythir, Rawan Abdulaziz Alshammari , et al. · 2024

Background: In healthcare, research is essential for improving disease diagnosis and treatment, patient outcomes, and resource management, while fostering evidence-based practice. However, conducting research in this sector can be challeng…

Ranking of Modifiable Lifestyle Risk Factors for Breast Cancer in Saudi Women: Population Attributable Risk and Nomogram Open

Rawabi M. Alsayer, Edward Devol, Amani Almeharish, Areej Alfattani, Alaa Alghamdi , et al. · 2024

Physical inactivity has the most significant modifiable health impact and is a major risk factor for breast cancer. Removing this risk factor would reduce the prevalence of breast cancer in the Saudi population by 23%. There is an immense …

Derivation and validation of Transform equations to convert historical Enhanced liver fibrosis (ELF) scores to modern equivalents Open

M. Gee, Agostino Palladino, H. Roma Levy, Edward Devol, David Kiaei · 2023

All transforms enabled accurate comparison of ELF scores generated by all historical algorithms to the current ADVIA Centaur / Atellica IM Analyzer ELF score. The transforms presented in this report should be used in systematic reviews and…

Development of a Cardiovascular Disease Risk Prediction Model: A Preliminary Retrospective Cohort Study of a Patient Sample in Saudi Arabia Open

Khaled Alabduljabbar, Mohammed Alkhalifah, Abdulaziz Aldheshe, Abdulelah Bin Shihah, Ahmed Abu‐Zaid , et al. · 2023

Saudi Arabia has an alarmingly high incidence of cardiovascular disease (CVD) and its associated risk factors. To effectively assess CVD risk, it is essential to develop tailored models for diverse regions and ethnicities using local popul…

Lifetime prevalence and treatment of mental disorders in Saudi youth and adolescents Open

Yasmin Altwaijri, Alan E. Kazdin, Abdullah Al‐Subaie, Abdulhameed Abdullah Alhabeeb, Sanaa Hyder , et al. · 2023

Previous global and regional studies indicate that adolescents and young adults (i.e., youth) are affected by various mental disorders with lifelong consequences. However, there are no national estimates of mental disorders prevalent among…

Lung transplantation outcomes in underweight recipients: A single center experience Open

Rayid Abdulqawi, Rana Saleh, Edward Devol, Haifa Aldakhil, Waleed Saleh , et al. · 2023

Our findings suggest that patients with BMIs of 13-17 kg/m² may be candidates for lung transplantation. Large multi-center cohort studies are needed to confirm the lower BMI limit for safely transplanting patients.

Implementation of new indicators of pediatric malnutrition and comparison to previous indicators Open

Mai Adnan Ezzat, Ebtsam Mohmmed Albassam, Eman Abdullah Aldajani, Raneem Abdulaziz Alaskar, Edward Devol · 2022

Background: Early identification of childhood malnutrition is imperative to improve overall health outcomes, and more importantly, to start early intervention to decrease the risk of future complications. This study aimed to evaluate new m…

Comparison of the safety and immunogenicity of the BNT-162b2 vaccine and the ChAdOx1 vaccine for solid organ transplant recipients: a prospective study Open

Aziza Ajlan, Tariq Ali, Hassan Aleid, Khalid Almeshari, Edward Devol , et al. · 2022

Descriptive analysis of clinical and laboratory findings in relation to changes in SARS-CoV-2 viral dynamics and cyclic threshold: a retrospective, single center observational study in patients treated with Hydroxychloroquine/Azithromycin combination therapy Open

Maha Al‐Amri, Edward Devol, Anwar B. Al-Otaibi, Faisal Albaiz, Mayyadah Alabdely , et al. · 2022

Background: Cases of undiagnosed pneumonia have emerged, and sequencing of respiratory samples indicated the presence of SARS-CoV-2 causing COVID-19. Patients with higher viral load and lower Ct values tend to have progressive disease and …

Comparison of the Safety and Immunogenicity of the BNT-162b2 Vaccine and the ChAdOx1 Vaccine for Solid Organ Transplant Recipients: A Prospective Study Open

Aziza Ajlan, Tariq Ali, Hassan Aleid, Khalid Almeshari, Edward Devol , et al. · 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its resulting disease, coronavirus disease 2019 (COVID-19), has spread to millions of people worldwide. Preliminary data from organ transplant recipients have shown…

Psychological distress reported by healthcare workers in Saudi Arabia during the COVID-19 pandemic: A cross-sectional study Open

Yasmin Altwaijri, Lisa Bilal, Amani Almeharish, Abdulrahman Binmuammar, Edward Devol , et al. · 2022

Introduction Few studies have considered the impact of COVID-19 on the mental health of healthcare workers (HCWs) in the Kingdom of Saudi Arabia (KSA). We estimated the prevalence and severity of psychological distress and characterized pr…

Tacrolimus-Induced Neurotoxicity in Early Post-Liver Transplant Saudi Patients: Incidence and Risk Factors Open

Dema A. Alissa, Delal Alkortas, Mohammed Al‐Sebayel, Rawan A. Almasuood, Wejdan Aburas , et al. · 2022

BACKGROUND Tacrolimus is a calcineurin inhibitor (CNI) commonly used as an immunosuppressant to prevent the rejection of organ transplants. After liver transplantation, it can cause early neurological complications, known as early calcineu…

Population-based survival for cancer patients in Saudi Arabia for the years 2005–2009 Open

Mohamed Aseafan, Edward Devol, Mahmoud Al-Ahwal, Riad Souissi, Reham Sindi , et al. · 2022

Epidemiology and Clinical Characteristics in Individuals with Confirmed SARS-CoV-2 Infection During the Early COVID-19 Pandemic in Saudi Arabia Open

Fatimah S. Alhamlan, Reem S. Almaghrabi, Edward Devol, Anwar Alotaibi, Saleh Alageel , et al. · 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the catastrophic coronavirus disease 2019 (COVID-19) global pandemic. This study aimed to provide epidemiologic and clinical characteristics of patients…

Prevalence and Epidemiological Trends in Mortality Due to COVID-19 in Saudi Arabia Open

Dema A. Alissa, Wejdan Aburas, Hajer Almudaiheem, Zohair Al Aseri, Fahad Alrabiah , et al. · 2021

Background: Coronavirus disease of 2019 (COVID-19) created a major public health emergency and an international concern. It is an infectious respiratory illness caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The internati…

Standard induction with basiliximab versus no induction in low immunological risk kidney transplant recipients: study protocol for a randomized controlled trial Open

Aziza Ajlan, Hassan Aleid, Tariq Ali, Hala Joharji, Khalid Almeshari , et al. · 2021

Cancer Survival in Saudi Arabia 2005-2009: Analysis of the Population-based Saudi Cancer Registry Open

Mohamed Aseafan, Edward Devol, Mahmoud Al-Ahwal, Riad Souissi, Reham Sindi , et al. · 2021

The Saudi Cancer Registry reported in 2007 the 5-year observed survival for the most common cancer sites for the years 1994-2004. In this report we looked at the cancer survival in the period 2005-2009 and evaluated the trend over the 15 y…

Epidemiology of Pancreatic Cancer in Saudi Arabia: A Retrospective Analysis of Pancreatic Cancer Diagnosed in Saudi Arabia Between 2004 and 2015 Open

Ibrahim Alghamdi, Majid A. Almadi, Fahad Alsohaibani, Mahmoud Mosli, Edward Devol , et al. · 2021

This study revealed a slight increase of the CIR and ASIR of pancreatic cancer among males and females of the Saudi population. Eastern region, Riyadh, and Tabuk had the highest overall ASIRs of pancreatic cancer among males, Riyadh, North…

Prevalence and Epidemiological Trends in Mortality Due to COVID-19 in Saudi Arabia Open

Dema A. Alissa, Wejdan Aburas, Hajer Almudaiheem, Zohair Al Aseri, Fahad Alrabiah , et al. · 2021

Cancer Survival in Saudi Arabia 2005-2009: Analysis of the Population-Based Saudi Cancer Registry Open

Mohamed Aseafan, Edward Devol, Mahmoud Al-Ahwal, Riad Souissi, Reham Sindi , et al. · 2021

Coping with the COVID-19 Pandemic’s Unique Challenges Associated with Medical Research: A Saudi Institution Approach Open

Amani Almeharish, Abdullah M. Assiri, Areej Alfattani, Edward Devol · 2020

The spread of COVID-19 has become a significant threat to economic activity throughout the world, and it has made life particularly difficult for research institutions. According to a report published by Spain's largest public research bod…

Elicitation of Health Utilities in Oncology in the Kingdom of Saudi Arabia Open

Michaël Iskedjian, Edward Devol, Mahmoud A. Elshenawy, Shouki Bazarbashi · 2020

PURPOSE Health utilities (HUs) are quantitative measures of quality of life that are used to derive outcomes such as quality-adjusted life years in cost-effectiveness analyses. In the Kingdom of Saudi Arabia, there are no HUs for cancer. T…

VP22.17: Chorioangioma: single tertiary care centre experience in Riyadh Open

Bashayer Saeed, Wesam Kurdi, Asma Tulbah, Edward Devol, Sultan Almugbel , et al. · 2020

Chorioangioma represent a challenge due to the rarity of the condition, paucity of sufficient management guidelines and controversies regarding the best invasive fetal therapy option. Most of the scientific evidence for clinical treatment …

Spontaneous Coronary Artery Dissection: Does Being Unemployed Matter? Insights from the GSCAD Registry Open

Amin Daoulah, Salem M. Al-Faifi, William T. Hurley, Abdulaziz Alasmari, Mohammed Rashid Ocheltree , et al. · 2020

Background: Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome (ACS) and sudden cardiac death. Physical or emotional stressors are the most commonly reported triggers for SCAD. Unempl…

MON-155 Retrospective Cross-Sectional Study to Assess the Utility of 30 vs 60 Minutes Serum Cortisol Value Attained During a Short Synacthen Test (SST) Open

Muhammad Imran Butt, Lama Amer, Hadeel Aljamei, Muhammad Riazuddin, N. A. M. Al-Zuhairy , et al. · 2020

Background SST is done to assess adrenal gland function by measuring basal serum cortisol followed by injecting 250 μg of Synacthen (ACTH) & measuring cortisol at 30 & 60 minutes. Design All patients over 14 years (adulthood age in the reg…

The Risk Of Seizure-Related Hospitalization Among Older Adults On Levetiracetam Monotherapy: A Retrospective Comparative Cohort Study Open

Huda Alzahrani, Haya Mohammad Almalag, Yazed AlRuthia, Fawaz Al‐Hussain, Bander Balkhi , et al. · 2019

This study suggests that older adults on old generation AEDs such as phenytoin, carbamazepine, and valproic acid appear to have a lower risk of seizure-related hospitalization compared to their counterparts on levetiracetam.

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