Edward Millgate
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View article: Acceptability of a Conversational Agent–Led Digital Program for Anxiety: Mixed Methods Study of User Perspectives
Acceptability of a Conversational Agent–Led Digital Program for Anxiety: Mixed Methods Study of User Perspectives Open
Background The prevalence of anxiety and depression is increasing globally, outpacing the capacity of traditional mental health services. Digital mental health interventions (DMHIs) provide a cost-effective alternative, but user engagement…
View article: Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care
Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care Open
Background Escalating mental health demand exceeds existing clinical capacity, necessitating scalable digital solutions. However, engagement remains challenging. Conversational agents can enhance engagement by making digital programs more …
View article: Acceptability of a Conversational Agent-led Digital Program for Anxiety: A Mixed-Methods Study of Patient Perspectives
Acceptability of a Conversational Agent-led Digital Program for Anxiety: A Mixed-Methods Study of Patient Perspectives Open
Background. Prevalence rates for anxiety and depression are increasing globally, outpacing the capacity of traditional mental health services. Digital Mental Health Interventions (DMHIs) offer a cost-effective solution, but user engagement…
View article: Domain-specific cognitive function in euthymic bipolar disorder: a systematic review and meta-analysis
Domain-specific cognitive function in euthymic bipolar disorder: a systematic review and meta-analysis Open
Background Euthymic bipolar disorder (BD) is associated with general and domain-specific cognitive impairment, which predicts poor occupational and social functioning. Methods We searched Embase, Medline, and PsycInfo for articles publishe…
View article: Corrigendum to “Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study” [Schizophr. Res. volume 225 (May 2023) 173–181]
Corrigendum to “Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study” [Schizophr. Res. volume 225 (May 2023) 173–181] Open
View article: PsyCog: A computerised mini battery for assessing cognition in psychosis
PsyCog: A computerised mini battery for assessing cognition in psychosis Open
View article: Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study Open
View article: Anterior Cingulate Glutamate Metabolites as a Predictor of Antipsychotic Response in First Episode Psychosis: data from the STRATA collaboration.
Anterior Cingulate Glutamate Metabolites as a Predictor of Antipsychotic Response in First Episode Psychosis: data from the STRATA collaboration. Open
Elevated brain glutamate has been implicated in non-response to antipsychotic medication in schizophrenia. Biomarkers that can accurately predict antipsychotic non-response from the first episode of psychosis (FEP) could allow stratificati…
View article: Neuropsychological differences between treatment-resistant and treatment-responsive schizophrenia: a meta-analysis
Neuropsychological differences between treatment-resistant and treatment-responsive schizophrenia: a meta-analysis Open
Antipsychotic treatment resistance affects up to a third of individuals with schizophrenia. Of those affected, 70–84% are reported to be treatment resistant from the outset. This raises the possibility that the neurobiological mechanisms o…
View article: Cross-sectional study comparing cognitive function in treatment responsive versus treatment non-responsive schizophrenia: evidence from the STRATA study
Cross-sectional study comparing cognitive function in treatment responsive versus treatment non-responsive schizophrenia: evidence from the STRATA study Open
Background 70%–84% of individuals with antipsychotic treatment resistance show non-response from the first episode. Emerging cross-sectional evidence comparing cognitive profiles in treatment resistant schizophrenia to treatment-responsive…
View article: The relationship between alexithymia and theory of mind: A systematic review
The relationship between alexithymia and theory of mind: A systematic review Open
Theory of Mind (ToM), the ability to represent the mental states of oneself and others, is an essential social skill disrupted across many psychiatric conditions. The transdiagnostic nature of ToM impairment means it is plausible that ToM …
View article: Demographic and clinical variables associated with response to clozapine in schizophrenia: a systematic review and meta-analysis
Demographic and clinical variables associated with response to clozapine in schizophrenia: a systematic review and meta-analysis Open
Clozapine is the only licensed pharmacotherapy for treatment-resistant schizophrenia. However, response to clozapine is variable. Understanding the demographic and clinical features associated with response to clozapine may be useful for p…
View article: A Taxonomy of Theory of Mind Tests and their relationship with Alexithymia
A Taxonomy of Theory of Mind Tests and their relationship with Alexithymia Open
View article: S62. COGNITIVE DEFICITS IN TREATMENT RESISTANT SCHIZOPHRENIA
S62. COGNITIVE DEFICITS IN TREATMENT RESISTANT SCHIZOPHRENIA Open
Background Schizophrenia (Sz) and other psychoses are complex mental disorders, characterised by sensory, cognitive and emotional symptoms, but mainly distinguished by positive and negative symptoms. Cognitive impairment is a core feature …
View article: QJE-STD-18-365.R2-Supplementary_Material – Supplemental material for No effect of age on emotion recognition after accounting for cognitive factors and depression
QJE-STD-18-365.R2-Supplementary_Material – Supplemental material for No effect of age on emotion recognition after accounting for cognitive factors and depression Open
Supplemental material, QJE-STD-18-365.R2-Supplementary_Material for No effect of age on emotion recognition after accounting for cognitive factors and depression by Jennifer Murphy, Edward Millgate, Hayley Geary, Caroline Catmur and Geoffr…
View article: Processing speed and fluid intelligence contribute towards decline in facial emotion recognition ability across the adult lifespan
Processing speed and fluid intelligence contribute towards decline in facial emotion recognition ability across the adult lifespan Open
A body of research suggests that advancing age is associated with decline in emotion recognition, though the factors that contribute towards this decline remain unclear. While previous research suggested that declining emotion recognition …
View article: Direct and indirect effects of age on interoceptive accuracy and awareness across the adult lifespan
Direct and indirect effects of age on interoceptive accuracy and awareness across the adult lifespan Open