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View article: Ethical considerations for research involving pregnant women with HIV and their children
Ethical considerations for research involving pregnant women with HIV and their children Open
Pregnant and postpartum women with HIV (PPWH) and their children have historically been excluded from certain research in the name of protection. This may, however, inadvertently exacerbate health disparities. While calls for their inclusi…
View article: Machine learning of blood haemoglobin and haematocrit levels via smartphone conjunctiva photography in Kenyan pregnant women: a clinical study protocol
Machine learning of blood haemoglobin and haematocrit levels via smartphone conjunctiva photography in Kenyan pregnant women: a clinical study protocol Open
Introduction Anaemia during pregnancy is a widespread health burden globally, especially in low- and middle-income countries, posing a serious risk to both maternal and neonatal health. The primary challenge is that anaemia is frequently u…
View article: Associations between nighttime or weekend deliveries and adverse maternal, birth, and neonatal outcomes: secondary analysis of the MANGO study in western Kenya
Associations between nighttime or weekend deliveries and adverse maternal, birth, and neonatal outcomes: secondary analysis of the MANGO study in western Kenya Open
Nighttime/weekend deliveries were associated with better maternal and birth outcomes, perhaps due to decreased emergency Caesarean deliveries for high-risk pregnancies or other factors. Greater attention to individual-level factors, such a…
View article: Care as repair, but whose responsibility? Front-line health workers’ resourcefulness in implementing a PMTCT tracing policy in Kenya
Care as repair, but whose responsibility? Front-line health workers’ resourcefulness in implementing a PMTCT tracing policy in Kenya Open
Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study expl…
View article: Cohort profile: measuring adverse pregnancy and newborn congenital outcomes (MANGO) study in Kenya
Cohort profile: measuring adverse pregnancy and newborn congenital outcomes (MANGO) study in Kenya Open
Purpose Pharmacovigilance (PV) systems to assess the safety of antiretroviral treatment used periconception and during pregnancy are lacking in low-resource settings with high HIV burdens, and strategies to guide their implementation are l…
View article: Human-centered design of an adapted differentiated service delivery model for pregnant and postpartum women living with HIV in Kenya
Human-centered design of an adapted differentiated service delivery model for pregnant and postpartum women living with HIV in Kenya Open
Differentiated service delivery (DSD) models for pregnant and postpartum women living with HIV (WLH) are lacking despite guidelines recommending DSD for this population. We used human-centered design (HCD) to develop a DSD model for pregna…
View article: Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qualitative findings from the KuwaFree! LiveFree! Study
Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qualitative findings from the KuwaFree! LiveFree! Study Open
Introduction Adolescents and young people living with HIV (AYPLHIV) face significant hurdles in adhering to daily oral antiretroviral therapy (ART). Long-acting (LA) ART, such as injectable cabotegravir and rilpivirine, may help overcome t…
View article: Implementing WHO Differentiated Service Delivery Model for Pregnant and Breastfeeding Women and Infants Living with HIV: Insights from Kenyan Healthcare Providers
Implementing WHO Differentiated Service Delivery Model for Pregnant and Breastfeeding Women and Infants Living with HIV: Insights from Kenyan Healthcare Providers Open
Background and Objective: Differentiated service delivery (DSD) is a strategy endorsed by the World Health Organization that simplifies and adapts human immunodeficiency (HIV) services to meet the needs of people living with HIV (PLHIV) wh…
View article: Stakeholder Perspectives on the Role of Peer Mentors in the Implementation of Long-Acting Antiretroviral Therapy for Use by Adolescents and Young People in Western Kenya: Findings from a Formative Study, KuwaFree! LiveFree!
Stakeholder Perspectives on the Role of Peer Mentors in the Implementation of Long-Acting Antiretroviral Therapy for Use by Adolescents and Young People in Western Kenya: Findings from a Formative Study, KuwaFree! LiveFree! Open
Long-acting antiretroviral treatment (LA ART) is a forthcoming option for adolescents and young people living with HIV (AYPLHIV), but perspectives on using peer mentors to implement LA ART for AYPLHIV are unknown. We conducted seven focus …
View article: Pharmacovigilance in Pregnancy Studies, Exposures and Outcomes Ascertainment, and Findings from Low- and Middle-Income Countries: A Scoping Review
Pharmacovigilance in Pregnancy Studies, Exposures and Outcomes Ascertainment, and Findings from Low- and Middle-Income Countries: A Scoping Review Open
The published pregnancy PV projects were largely centered in Africa and concerned with infectious diseases. This may reflect the disease burden in LMICs but also funding priorities from high-income countries. As the prevalence of non-commu…
View article: Cost‐effectiveness analysis of alternative screening strategies for the detection of cervical cancer among women in rural areas of Western Kenya
Cost‐effectiveness analysis of alternative screening strategies for the detection of cervical cancer among women in rural areas of Western Kenya Open
While the incidence of cervical cancer has dropped in high‐income countries due to organized cytology‐based screening programs, it remains the leading cause of cancer death among women in Eastern Africa. Therefore, the World Health Organiz…
View article: Factors Associated With Intrapartum Detectable Viral Load Among Hiv Positive Parturients at Riley Mother and Baby Hospital, Eldoret-Kenya.
Factors Associated With Intrapartum Detectable Viral Load Among Hiv Positive Parturients at Riley Mother and Baby Hospital, Eldoret-Kenya. Open
Background Vertical transmission of Human Immuno-deficiency Virus (HIV) can occur during pregnancy, labour, and delivery, or in breastfeeding. Detectable viral load among pregnant women is the strongest predictor. Knowledge of factors asso…
View article: Understanding Women’s Preferences for Prevention of Mother-to-Child HIV Transmission Services in Kenya
Understanding Women’s Preferences for Prevention of Mother-to-Child HIV Transmission Services in Kenya Open
Background and Objective Understanding the preferences of women living with HIV (WLH) for the prevention of mother-to-child HIV transmission (PMTCT) services is important to ensure such services are person-centered. Methods From April to D…
View article: Labour pain relief practice by maternal health care providers at a tertiary facility in Kenya: An institution-based descriptive survey
Labour pain relief practice by maternal health care providers at a tertiary facility in Kenya: An institution-based descriptive survey Open
Background Although pain relief is a crucial component of modern obstetric care, it remains a poorly established service in sub-Saharan countries such as Kenya. Maternal health care providers have an extensive role to play in meeting the a…
View article: Prevalence and Factors Associated with Contraceptive Use Among Females Living with HIV at Moi Teaching and Referral Hospital, Eldoret, Kenya
Prevalence and Factors Associated with Contraceptive Use Among Females Living with HIV at Moi Teaching and Referral Hospital, Eldoret, Kenya Open
Objective: To assess the prevalence of, and the factors associated with, contraceptive use among females living with HIV at Moi Teaching and Referral Hospital, Eldoret, Kenya. Methods: A cross-sectional study with a sample including a tota…
View article: VALIDATION OF A MODIFIED OBSTETRIC EARLY WARNING SYSTEM FOR PREDICTING SEVERE MATERNAL OUTCOME AT A TERTIARY REFERRAL FACILITY IN WESTERN KENYA
VALIDATION OF A MODIFIED OBSTETRIC EARLY WARNING SYSTEM FOR PREDICTING SEVERE MATERNAL OUTCOME AT A TERTIARY REFERRAL FACILITY IN WESTERN KENYA Open
Background: Maternal ‘near-miss’ and deaths, together termed severe maternal outcome(SMO) follow a pattern of deterioration that can be predicted and prevented. To prevent SMO, a Modified Early Obstetric Warning System (MOEWS) for tracking…
View article: The use, adherence, and evaluation of interactive text-messaging among women admitted to prevention of mother-to-child transmission of HIV care in Kenya (WelTel PMTCT)
The use, adherence, and evaluation of interactive text-messaging among women admitted to prevention of mother-to-child transmission of HIV care in Kenya (WelTel PMTCT) Open
Background To improve future mobile health (mHealth) interventions in resource-limited settings, knowledge of participants’ adherence to interactive interventions is needed, but previous studies are limited. We aimed to investigate how wom…
View article: Comparing adverse maternal and perinatal outcomes in primary caesarean delivery during first versus second-stage of labour in Kenya: An institution-based cohort study
Comparing adverse maternal and perinatal outcomes in primary caesarean delivery during first versus second-stage of labour in Kenya: An institution-based cohort study Open
Background As caesarean delivery rates continue to increase globally, so are the number of second-stage caesarean deliveries. Second-stage caesareans may carry additional risk of complications for both the mother and fetus owing to fetal h…
View article: Preferences of Pregnant and Postpartum Women for Differentiated Service Delivery in Kenya
Preferences of Pregnant and Postpartum Women for Differentiated Service Delivery in Kenya Open
Background: Differentiated service delivery models are implemented by HIV care programs globally, but models for pregnant and postpartum women living with HIV (PPWH) are lacking. We conducted a discrete choice experiment to determine women…
View article: Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis
Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis Open
Medicines for Malaria Venture, WHO, and the Worldwide Antimalarial Resistance Network funded by the Bill & Melinda Gates Foundation.
View article: Occurrence of Research Misconduct and Institutional Capacity to Prevent and Manage Research Misconduct-Perspectives from Kenyan Research Regulators
Occurrence of Research Misconduct and Institutional Capacity to Prevent and Manage Research Misconduct-Perspectives from Kenyan Research Regulators Open
Background Research misconduct is often defined as fabrication, falsification and plagiarism. Its occurrence is associated with individual, institutional, national and global factors. Researcher perceptions of weak or non-existent institut…
View article: Provision of labour analgesia and its related barriers among maternal health care providers in Kenya: An institution-based descriptive survey.
Provision of labour analgesia and its related barriers among maternal health care providers in Kenya: An institution-based descriptive survey. Open
Background: Although pain relief is a key component of modern obstetric care, it remains a poorly established service in sub-Saharan countries, such as Kenya. Maternal health care providers have an extensive role to play in meeting the ana…
View article: Provision of labour analgesia and its related barriers among maternal healthcare providers in Kenya: an institutional-based descriptive survey.
Provision of labour analgesia and its related barriers among maternal healthcare providers in Kenya: an institutional-based descriptive survey. Open
Background: Although pain relief is a key component of modern obstetric care, it remains a poorly established service in sub-Saharan countries such as Kenya. Maternal health care providers have an extensive role to play in meeting the anal…
View article: Predicting neurodevelopmental risk in children born to mothers living with HIV in Kenya: protocol for a prospective cohort study (Tabiri Study)
Predicting neurodevelopmental risk in children born to mothers living with HIV in Kenya: protocol for a prospective cohort study (Tabiri Study) Open
Introduction For the growing number of children with in utero and postpartum exposure to HIV and/or antiretrovirals, it is unclear which exposures or risk factors play a significant role in predicting worse neurodevelopmental outcomes. Thi…
View article: Health related quality of life among pregnant women living with HIV in Kenya, results from comparing a patient generated index and the Euroqol 5 dimension 3 level
Health related quality of life among pregnant women living with HIV in Kenya, results from comparing a patient generated index and the Euroqol 5 dimension 3 level Open
Background Standardized tools are used to measure health-related quality of life (HRQoL) and they focus on selected physical, emotional, and social functioning. This approach may miss out on the heterogeneity of HRQoL among various sub-pop…