Eeva Broberg
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View article: Epidemiological and Clinical Insights into Enterovirus Circulation in Europe, 2018–2023: A Multicenter Retrospective Surveillance Study
Epidemiological and Clinical Insights into Enterovirus Circulation in Europe, 2018–2023: A Multicenter Retrospective Surveillance Study Open
Background Enteroviruses (EV) cause yearly outbreaks with severe infections, particularly in young children. This study investigates EV circulation, age, and clinical presentations in Europe from 2018 to 2023. Methods Aggregated data were …
View article: External quality assessment of molecular detection and variant typing of SARS-CoV-2 in European expert laboratories in 2023
External quality assessment of molecular detection and variant typing of SARS-CoV-2 in European expert laboratories in 2023 Open
The COVID-19 pandemic highlighted the importance of laboratory preparedness. Regular monitoring of diagnostic tools via external quality assessments (EQAs) is key to maintaining robust public health response service. We hereby conducted a …
View article: Impact of SARS-CoV-2 variant mutations on susceptibility to monoclonal antibodies and antiviral drugs: a non-systematic review, April 2022 to October 2024
Impact of SARS-CoV-2 variant mutations on susceptibility to monoclonal antibodies and antiviral drugs: a non-systematic review, April 2022 to October 2024 Open
Background Monoclonal antibodies (mAbs) and antiviral drugs have emerged as additional tools for treatment of COVID-19. Aim We aimed to review data on susceptibility of 14 SARS-CoV-2 variants to mAbs and antiviral drugs authorised in the E…
View article: Antigenic changes in influenza A(H3N2) driven by genetic evolution: Insights from virological surveillance, EU/EEA, week 40/2023 to week 9/2024
Antigenic changes in influenza A(H3N2) driven by genetic evolution: Insights from virological surveillance, EU/EEA, week 40/2023 to week 9/2024 Open
Background During the 2023/24 influenza season in the European Union/European Economic Area (EU/EEA), influenza viruses A(H1N1)pdm09, A(H3N2) and B/Victoria viruses were co-circulating. Aim We aimed to describe the circulating influenza vi…
View article: Co-circulation of seasonal influenza A(H1N1)pdm09, A(H3N2) and B/Victoria lineage viruses with further genetic diversification, EU/EEA, 2022/23 influenza season
Co-circulation of seasonal influenza A(H1N1)pdm09, A(H3N2) and B/Victoria lineage viruses with further genetic diversification, EU/EEA, 2022/23 influenza season Open
Background Influenza viruses can cause large seasonal epidemics with high healthcare impact and severity as they continually change their virological properties such as genetic makeup over time. Aim We aimed to monitor the characteristics …
View article: Parechovirus A Circulation and Testing Capacities in Europe, 2015–2021
Parechovirus A Circulation and Testing Capacities in Europe, 2015–2021 Open
Parechovirus infections usually affect neonates and young children; manifestations vary from asymptomatic to life-threatening. We describe laboratory capacity in Europe for assessing parechovirus circulation, seasonality, and epidemiology.…
View article: Respiratory syncytial virus infections – recent developments providing promising new tools for disease prevention
Respiratory syncytial virus infections – recent developments providing promising new tools for disease prevention Open
Preview this article: Respiratory syncytial virus infections – recent developments providing promising new tools for disease prevention, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/28/49/eurosurv-…
View article: Systematic review of seroprevalence of SARS-CoV-2 antibodies and appraisal of evidence, prior to the widespread introduction of vaccine programmes in the WHO European Region, January–December 2020
Systematic review of seroprevalence of SARS-CoV-2 antibodies and appraisal of evidence, prior to the widespread introduction of vaccine programmes in the WHO European Region, January–December 2020 Open
Objectives Systematic review of SARS-CoV-2 seroprevalence studies undertaken in the WHO European Region to measure pre-existing and cumulative seropositivity prior to the roll out of vaccination programmes. Design A systematic review of th…
View article: Comparative study between virus neutralisation testing and other serological methods detecting anti-SARS-CoV-2 antibodies in Europe, 2021
Comparative study between virus neutralisation testing and other serological methods detecting anti-SARS-CoV-2 antibodies in Europe, 2021 Open
One consequence of the ongoing coronavirus disease pandemic was the rapid development of both in-house and commercial serological assays detecting anti-SARS-CoV-2 antibodies, in an effort to reliably detect acute and past SARS-CoV-2 infect…
View article: New perspectives on respiratory syncytial virus surveillance at the national level: lessons from the COVID-19 pandemic
New perspectives on respiratory syncytial virus surveillance at the national level: lessons from the COVID-19 pandemic Open
Learning from the COVID-19 pandemic and considering the effects of this pandemic, we provide recommendations that can guide towards sustainable RSV surveillance with the potential to be integrated into the broader perspective of respirator…
View article: Seasonality of respiratory syncytial virus and its association with meteorological factors in 13 European countries, week 40 2010 to week 39 2019
Seasonality of respiratory syncytial virus and its association with meteorological factors in 13 European countries, week 40 2010 to week 39 2019 Open
Background Respiratory syncytial virus (RSV) is the predominant cause of clinical pneumonia among infants and young children, often peaking during the winter months in temperate regions. Aim To describe RSV seasonality in 13 European count…
View article: Seroprevalence of SARS-CoV-2 antibodies prior to the widespread introduction of vaccine programmes in the WHO European Region, January - December 2020: a systematic review
Seroprevalence of SARS-CoV-2 antibodies prior to the widespread introduction of vaccine programmes in the WHO European Region, January - December 2020: a systematic review Open
Background Seroprevalence surveys are essential to assess the age-specific prevalence of pre-existing cross-reactive antibodies in the population with the emergence of a novel pathogen; to measure population cumulative seroincidence of inf…
View article: Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020
Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020 Open
Background Reliable testing for SARS-CoV-2 is key for the management of the COVID-19 pandemic. Aim We estimate diagnostic accuracy for nucleic acid and antibody tests 5 months into the COVID-19 pandemic, and compare with manufacturer-repor…
View article: Point of Care Testing for Infectious Disease in Europe: A Scoping Review and Survey Study
Point of Care Testing for Infectious Disease in Europe: A Scoping Review and Survey Study Open
Background: Point of care testing (POCT) for infectious diseases is testing conducted near the patient. It allows clinicians to offer the most appropriate treatment more quickly. As POCT devices have increased in accuracy and become more c…
View article: Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe Open
In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016-2018. Most E30 cases affected…
View article: Recommendations for respiratory syncytial virus surveillance at the national level
Recommendations for respiratory syncytial virus surveillance at the national level Open
Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infections and hospitalisations among young children and is globally responsible for many deaths in young children, especially in infants aged <6 months. …
View article: COVID-19 research priorities for non-pharmaceutical public health and social measures
COVID-19 research priorities for non-pharmaceutical public health and social measures Open
Europe is in the midst of a COVID-19 epidemic and a number of non-pharmaceutical public health and social measures have been implemented, in order to contain the transmission of severe acute respiratory syndrome coronavirus 2. These measur…
View article: Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe Open
In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most E30 cases affected…
View article: Variable Sensitivity of SARS-CoV-2 Molecular Detection in European Expert Laboratories: External Quality Assessment, June and July 2020
Variable Sensitivity of SARS-CoV-2 Molecular Detection in European Expert Laboratories: External Quality Assessment, June and July 2020 Open
During the ongoing coronavirus disease 2019 (COVID-19) outbreak, robust detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a key element for clinical management and to interrupt transmission chains. We organized a…
View article: First Cases of Coronavirus Disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
First Cases of Coronavirus Disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020 Open
In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020. We detail the first European cases. As at 21 February, nine European countries reported 47 cases. Among 38 cases studied, 21 were linked to two clusters in …
View article: Automated digital reporting of clinical laboratory information to national public health surveillance systems, results of a EU/EEA survey, 2018
Automated digital reporting of clinical laboratory information to national public health surveillance systems, results of a EU/EEA survey, 2018 Open
Background Timely reporting of microbiology test results is essential for infection management. Automated, machine-to-machine (M2M) reporting of diagnostic and antimicrobial resistance (AMR) data from laboratory information management syst…
View article: Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020
Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020 Open
We reviewed the clinical performance of SARS-CoV-2 nucleic acid, viral antigen and antibody tests based on 94739 test results from 157 published studies and 20205 new test results from 12 EU/EEA Member States. Pooling the results and consi…
View article: Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020
Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020 Open
We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to…
View article: First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020 Open
In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020. We detail the first European cases. As at 21 February, nine European countries reported 47 cases. Among 38 cases studied, 21 were linked to two clusters in …
View article: Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020
Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries, January 2020 Open
Timely detection of novel coronavirus (2019-nCoV) infection cases is crucial to interrupt the spread of this virus. We assessed the required expertise and capacity for molecular detection of 2019-nCoV in specialised laboratories in 30 Euro…
View article: Alternating patterns of seasonal influenza activity in the WHO European Region following the 2009 pandemic, 2010‐2018
Alternating patterns of seasonal influenza activity in the WHO European Region following the 2009 pandemic, 2010‐2018 Open
Background Influenza virus infections are common and lead to substantial morbidity and mortality worldwide. We characterized the first eight influenza epidemics since the 2009 influenza pandemic by describing the distribution of viruses an…
View article: Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017 Open
Background Respiratory syncytial virus (RSV) is a major contributor to lower respiratory tract infections worldwide and several vaccine candidates are currently in development. Following vaccine introduction, reliable RSV surveillance shou…
View article: Piloting a surveillance system for HIV drug resistance in the European Union
Piloting a surveillance system for HIV drug resistance in the European Union Open
Background A steady increase in HIV drug resistance (HIVDR) has been demonstrated globally in individuals initiating first-line antiretroviral therapy (ART). To support effective use of ART and prevent spread of HIVDR, monitoring is essent…
View article: Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018
Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018 Open
An upsurge in Echovirus 30 (E30) infections, associated with meningitis/meningoencephalitis, has been observed in Denmark, Germany, the Netherlands, Norway and Sweden in the period April to September 2018, compared with 2015–2017. In total…
View article: Recommendations for enterovirus diagnostics and characterisation within and beyond Europe
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe Open