Ehab M. M. Ali
YOU?
Author Swipe
View article: Salen‐Type Copper(II) Complexes: Synthesis, Characterization, Computational Studies, Molecular Docking, Anticancer Potential, and Pharmacokinetic Prediction
Salen‐Type Copper(II) Complexes: Synthesis, Characterization, Computational Studies, Molecular Docking, Anticancer Potential, and Pharmacokinetic Prediction Open
Transition metal complexes are considered a significant treatment for cancer diseases because of their efficacy toward cancer cells. However, most of these compounds have limited potential toward cancer cells due to their organic backbone …
View article: Synthesis, crystal structural description, DNA binding, molecular docking, and anticancer evaluation of the novel platinum(IV) supramolecular complex
Synthesis, crystal structural description, DNA binding, molecular docking, and anticancer evaluation of the novel platinum(IV) supramolecular complex Open
View article: RETRACTED: El-Gowily et al. Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. Pharmaceuticals 2021, 14, 254
RETRACTED: El-Gowily et al. Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. Pharmaceuticals 2021, 14, 254 Open
The journal retracts the article titled “Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in …
View article: "Smartwatch Detection of Cardiac Arrhythmias: A Systematic Review of Accuracy, Clinical Utility, and Limitations"
"Smartwatch Detection of Cardiac Arrhythmias: A Systematic Review of Accuracy, Clinical Utility, and Limitations" Open
View article: Synergetic effect of doxorubicin and avenanthramide C on VDAC2/MTCH1 mitochondrial axis in breast cancer cells.
Synergetic effect of doxorubicin and avenanthramide C on VDAC2/MTCH1 mitochondrial axis in breast cancer cells. Open
The DOX-AVC combination demonstrated a potent synergistic effect, enhancing apoptosis in BC cells by modulating mitochondrial pathways. This approach may provide a promising strategy for reducing chemotherapy side effects in BC treatment. …
View article: Impact of camel milk lactoferrin peptides against breast cancer cells: in silico and in vitro study
Impact of camel milk lactoferrin peptides against breast cancer cells: in silico and in vitro study Open
Background and Aims Breast cancer remains a significant global health concern, necessitating the exploration of novel therapeutic strategies. Despite advancements in cancer therapeutics, effective treatments with minimal side effects remai…
View article: Improving the Cytotoxic Activity of Hinokitiol from Drug-Loaded Phytosomal Formulation Against Breast Cancer Cell Lines
Improving the Cytotoxic Activity of Hinokitiol from Drug-Loaded Phytosomal Formulation Against Breast Cancer Cell Lines Open
Hinokitiol-loaded phytosomes demonstrate promising anticancer efficacy against breast cancer cells, highlighting their potential as targeted therapeutic agents for breast cancer therapy.
View article: Tri-spectroscopically evaluation of some selected Saudi medicinal plants for potential medical applications: UV-Visible, FTIR, and GCMS Analysis
Tri-spectroscopically evaluation of some selected Saudi medicinal plants for potential medical applications: UV-Visible, FTIR, and GCMS Analysis Open
The unique botanical diversity of Saudi Arabia has inspired many researchers to prospect deeply in its components. Therefore, this study was designed to identify biomolecular structure of Senna italica, Cymbopogon schoenanthus, Artemisia J…
View article: Correction: Jamal et al. Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells. Nanomaterials 2022, 12, 4029
Correction: Jamal et al. Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells. Nanomaterials 2022, 12, 4029 Open
In the original publication [...]
View article: Prediction of anticancer peptides derived from the true lectins of Phoenix dactylifera and their synergetic effect with mitotane
Prediction of anticancer peptides derived from the true lectins of Phoenix dactylifera and their synergetic effect with mitotane Open
Background and aims: Cancer continues to be a significant source of both illness and death on a global scale, traditional medicinal plants continue to serve as a fundamental resource of natural bioactive compounds as an alternative source …
View article: Synergistic effects of bee venom, hesperidin, and piperine with tamoxifen on apoptotic and angiogenesis biomarker molecules against xerographic MCF-7 injected rats
Synergistic effects of bee venom, hesperidin, and piperine with tamoxifen on apoptotic and angiogenesis biomarker molecules against xerographic MCF-7 injected rats Open
View article: Novel styryl-heterocyclic hybrids: Synthesis, characterization and anticancer activity
Novel styryl-heterocyclic hybrids: Synthesis, characterization and anticancer activity Open
Novel styryl-heterocyclic hybrids were designed and synthesized via Knoevenagel condensation reaction between 4-(4-((5-(((4-methyl-2-oxo-2H-chromen-7-yl)oxy)methyl)-1,3,4-oxadiazol-2-yl)methyl)piperazin-1-yl)benzaldehyde and indolenine (ve…
View article: Resveratrol-based Schiff base derivatives: Synthesis, characterization and cytotoxic study
Resveratrol-based Schiff base derivatives: Synthesis, characterization and cytotoxic study Open
New resveratrol-based Schiff base derivatives (1,2,4-triazole Schiff base derivatives 5a-d and hydrazide Schiff base derivatives 7a-d) were designed, synthesized via Schiff base reaction in the presence of H2SO4 as a catalyst in yield (91.…
View article: Enhancing Ezetimibe Anticancer Activity Through Development of Drug Nano-Micelles Formulations: A Promising Strategy Supported by Molecular Docking
Enhancing Ezetimibe Anticancer Activity Through Development of Drug Nano-Micelles Formulations: A Promising Strategy Supported by Molecular Docking Open
These findings suggest that F5 could serve as a proficient drug delivery system in augmenting the cytotoxic activity of ezetimibe against breast cancer.
View article: Regulation of Protein-Induced Apoptosis and Autophagy in Human Hepatocytes Treated with Metformin and Paclitaxel In Silico and In Vitro
Regulation of Protein-Induced Apoptosis and Autophagy in Human Hepatocytes Treated with Metformin and Paclitaxel In Silico and In Vitro Open
Metformin and paclitaxel therapy offer promising outcomes in the treatment of liver cancer. Combining paclitaxel with metformin enhances treatment effectiveness and mitigates the adverse effects associated with paclitaxel alone. This study…
View article: CCDC 2096540: Experimental Crystal Structure Determination
CCDC 2096540: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2164614: Experimental Crystal Structure Determination
CCDC 2164614: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2164546: Experimental Crystal Structure Determination
CCDC 2164546: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Exploring the Enhanced Antiproliferative Activity of Turmeric Oil and 6-Mercaptopurine in a Combined Nano-Particulate System Formulation
Exploring the Enhanced Antiproliferative Activity of Turmeric Oil and 6-Mercaptopurine in a Combined Nano-Particulate System Formulation Open
6-Mercaptopurine (6-MP) is a chemotherapeutic agent with inadequate efficacy due to its poor aqueous solubility and limited bioavailability. Turmeric oil is a naturally occurring bioactive substance obtained from the rhizomes of Curcuma lo…
View article: Synthesis, structure characterization and antitumor activities of copper and cobalt thiocyanate complexes with 3-acetlpyridine ligand
Synthesis, structure characterization and antitumor activities of copper and cobalt thiocyanate complexes with 3-acetlpyridine ligand Open
View article: Synthesis, Crystal Structure, DFT, and Anticancer Activity of Some Imine-Type Compounds via Routine Schiff Base Reaction: An Example of Unexpected Cyclization to Oxazine Derivative
Synthesis, Crystal Structure, DFT, and Anticancer Activity of Some Imine-Type Compounds via Routine Schiff Base Reaction: An Example of Unexpected Cyclization to Oxazine Derivative Open
The synthesis, characterization, and anticancer properties of three imine-type compounds 1–3 and an unexpected oxazine derivative 4 are presented. The reaction of p-dimethylaminobenzaldehyde or m-nitrobenzaldehyde with hydroxylamine hydroc…
View article: CCDC 2237019: Experimental Crystal Structure Determination
CCDC 2237019: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2237018: Experimental Crystal Structure Determination
CCDC 2237018: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2203351: Experimental Crystal Structure Determination
CCDC 2203351: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Potential Anticancer Activity of Juniperus procera and Molecular Docking Models of Active Proteins in Cancer Cells
Potential Anticancer Activity of Juniperus procera and Molecular Docking Models of Active Proteins in Cancer Cells Open
Medicinal plants provide a wide range of active compounds that can be exploited to create novel medicines with minimal side effects. The current study aimed to identify the anticancer properties of Juniperus procera (J. procera) leaves. He…
View article: Tuning anticancer properties and DNA-binding of Pt(<scp>ii</scp>) complexes <i>via</i> alteration of nitrogen softness/basicity of tridentate ligands
Tuning anticancer properties and DNA-binding of Pt(<span>ii</span>) complexes <i>via</i> alteration of nitrogen softness/basicity of tridentate ligands Open
The article illustrates the design flexibility of tridentate ligands and the resultant platinum complexes, highlighting the impact of this design flexibility on the anticancer potential.
View article: Biochemical studies on the effect of prostaglandin inhibitors and willow bark extract on liver cirrhosis induced by acetylsalicylate in rats
Biochemical studies on the effect of prostaglandin inhibitors and willow bark extract on liver cirrhosis induced by acetylsalicylate in rats Open
Prostaglandins (PGs) are arachidonic acid metabolites produced by the action of the enzyme cyclooxygenase (COX).Although PGs are important mediators of inflammation in various diseases, The deciduous herb, Salix mucronata Thunb (commonly c…
View article: Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells
Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells Open
6-Mercaptopurine (6-MP) is a well-known immunosuppressive medication with proven anti-proliferative activities. 6-MP possesses incomplete and highly variable oral absorption due to its poor water solubility, which might reduce its anti-can…
View article: CCDC 2161727: Experimental Crystal Structure Determination
CCDC 2161727: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Potential Anticancer Activities and Catalytic Oxidation Efficiency of Platinum(IV) Complex
Potential Anticancer Activities and Catalytic Oxidation Efficiency of Platinum(IV) Complex Open
The treatment of an aqueous acetonitrile solution of chloroplatinic acid hydrate H2PtCl6.xH2O and pyridine-2-carbaldehyde-oxime (paOH) in the presence of potassium thiocyanate at room temperature (25°) led to the formation of a new Pt(IV) …