Ehsan Aali
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View article: Effects of combination of melatonin and L-carnitine on in vitro maturation in mouse oocytes: An experimental study
Effects of combination of melatonin and L-carnitine on in vitro maturation in mouse oocytes: An experimental study Open
Background: Melatonin and L-carnitine are free radical scavengers with antiapoptotic and antioxidant properties that improve oocyte development. Objective: This study aimed to find the possible effect of combining 2 antioxidant agents of m…
Reduced ischemia‐reperfusion oxidative stress injury by melatonin and N‐acetylcysteine in the male rat brain Open
Middle cerebral artery occlusion (MCAO) is a model for inducing ischemic stroke in rodents, leading to devastating brain damage. Oxidative stress (OS) plays a crucial role in the pathogenesis of ischemia. In this study, the effect of melat…
Anti-apoptotic effects of minocycline on doxorubicin-induced cardiotoxicity in male Wistar rats Open
Background and Aim: Doxorubicin is an effective chemotherapeutic agent. However, use of this drug is limited due to its dose-dependent cardiotoxicity. Activation of apoptotic pathways in myocardial tissue plays an important role in doxorub…
Effect of vitamin D vaginal suppository on sexual functioning among postmenopausal women: A three-arm randomized controlled clinical trial Open
This corrects the article "Effect of vitamin D vaginal suppository on sexual functioning among postmenopausal women: A three-arm randomized controlled clinical trial" on page 208.
The Synergistic Glucose-lowering Effects of Metformin and Bavachinin on Type II Diabetic Rats Open
Background: Diabetes is one of the most prevalent endocrine disorders in humans, and its first-line medication is metformin. Peroxisome proliferator-activated receptor gamma (PPAR–γ) agonists are the adjuncts to metformin. Bavachinin is a …
View article: <scp>ChitoHeal</scp> gel use on the nasal site for prevention of <scp>N95</scp> masks caused pressure injuries: A randomised clinical trial
<span>ChitoHeal</span> gel use on the nasal site for prevention of <span>N95</span> masks caused pressure injuries: A randomised clinical trial Open
Prolonged use of personal protective equipment can cause pressure injuries on the skin. The current study was conducted with the aim of investigating the effect of ChitoHeal gel on the nasal site on the prevention of N 95 masks that caused…
Evaluation of Authenticity in Honey Samples from Qazvin, Iran Open
Adulteration of honey is a major problem in the world, due to its high nutritional value and the expensive cost of honey. Thus, the quality of honey produced in different regions must be assessed to protect the rights of consumers. The stu…
Effect of vitamin D vaginal suppository on sexual functioning among postmenopausal women: A three-arm randomized controlled clinical trial Open
Objective Vaginal atrophy, the second most common complication of menopause, can lead to sexual dysfunction. This study evaluated the effect of a vitamin D vaginal suppository on sexual functioning in postmenopausal women.Methods This thre…
Cardioprotective effects of minocycline against doxorubicin-induced cardiotoxicity Open
Min reduced Dox-induced cardiotoxicity. The anti-oxidant and anti-inflammatory properties of Min may contribute to its protective effects.
View article: Activity of meropenem-vaborbactam against different beta-lactamase producing Klebsiella pneumoniae and Escherichia coli isolates in Iran
Activity of meropenem-vaborbactam against different beta-lactamase producing Klebsiella pneumoniae and Escherichia coli isolates in Iran Open
We evaluated the activity of meropenem-vaborbactam against different beta-lactamase producing Klebsiella pneumoniae and Escherichia coli isolates. In our study antibiotic susceptibility testing, double disk synergy test, modified Hodge tes…
A study on the correlation between smoking and non-enzymatic antioxidant factors of the saliva of healthy smokers and non-smokers Open
Objective: Smoking is among the most destructive habit which has numerous effects on the body. The chemical competent of cigarettes destroy the anti-oxidant content of the saliva. In this study, the concentration of albumin and uric acid o…
Anticonvulsive and Antioxidant Effects of Pioglitazone on Pilocarpine-induced Seizures in Mice Open
Background: Epilepsy is a neurological disorder caused by uncontrollable discharge of action potentials from neurons in the brain. After a seizure, oxidative stress may cause a significant neuronal damage. In the current study, we assessed…
A systematic review of the risk factors of honey consumption and their limit despite the beneficial nutritional properties and healing Open
A systematic review of the risk factors of honey consumption and their limit despite the beneficial nutritional properties and healing
The Effects of Oral Silver Nanoparticles and Propolis on the Level of Lipid Peroxidation in Male Wistar Rats Open
Background: Oxidative stress is a leading factor in developing silver nanoparticle-induced toxicity. Objective: This study evaluated the effects of oral prescription of different doses of silver nanoparticles and propolis on lipid peroxida…
A Promising Approach to Improving COVID-19 Symptoms: Using Antioxidant Supplements Open
Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease could progress to Acute Respiratory Distress Syndrome (ARDS). The immune cells’ migration in response to the virus leads to cell death by releasing o…
Cardioprotective Effects of Mebudipine in a Rat Model of Doxorubicin-Induced Heart Failure. Open
The administration of mebudipine to HF animals, akin to amlodipine, palliated the clinical and biochemical signs of the disease in the present study. The abstract was presented in the Iranian Congress of Physiology and Pharmacology as a po…
Cytotoxic Effects of Methanolic Extract of Ferula assa-foetida on SKOV-3 and MIA PaCa-2 Cells Open
Introduction: Previous studies have demonstrated cytotoxic effects of Ferula assa-foetida. In the present study, the anti-proliferative effect of this plant on two species of cancer cells related to pancreatic cancer (MIA PaCa-2) and ovari…
The Antihelminthic Drug, Mebendazole, Induces Apoptosis in Adult T-cell Leukemia/Lymphoma Cancer Cells: In-vitro Trial Open
Background: Adult T-cell leukemia/lymphoma (ATLL) is a poor prognostic Hematopoietic malignancy with various therapeutic challenges, which had been classified as non-Hodgkin lymphoma. The Drug switching, as a novel, innovative and promisin…
Anticonvulsive and Antioxidant Effects of Pioglitazone on Pentylenetetrazole-induced Seizures in Rats Open
Background: Epilepsy is a neurologic dysfunction caused by abnormal electrical activity in the brain. Oxidative stress is involved in the seizure-induced brain damage. Objective: This study aimed to evaluate the anticonvulsant and antioxid…
Effects of Chronic Administration of Pioglitazone on Learning and Memory in Rat Model of Streptozotocin-induced Alzheimer’s Disease Open
Background: Alzheimer’s Disease (AD) is a chronic neurodegenerative disease characterized by abnormal protein accumulation, synaptic dysfunction, and cognitive impairment. Peroxisome Proliferator-Activated Receptor-γ (PPARγ) play a crucial…
View article: Enhancing the Therapeutic Efficacy of Daunorubicin and Mitoxantrone with Bavachinin, Candidone, and Tephrosin
Enhancing the Therapeutic Efficacy of Daunorubicin and Mitoxantrone with Bavachinin, Candidone, and Tephrosin Open
The capability of flavonoids in sensitizing cancer cells was demonstrated in numerous works to chemotherapy and converse multidrug resistance by modulating efflux pumps and apoptosis mechanisms. Three flavonoids, namely, bavachinin, tephro…
Neuroendocrine Role of Kisspeptin-Neurokinin B-Dynorphin Pathway in Male Fertility and its Correlation with Melatonin Open
Neuroendocrine Role of Kisspeptin-Neurokinin B-Dynorphin Pathway in Male Fertility and its Correlation with Melatonin
Association Study of the ATP - Binding Cassette Transporter A1 (ABCA1) Rs2230806 Genetic Variation with Lipid Profile and Coronary Artery Disease Risk in an Iranian Population Open
BACKGROUND: ATP - binding cassette transporter A1 (ABCA1) plays essential roles in the biogenesis of high -density lipoprotein - cholesterol. Variations in the ABCA1 gene may influence the risk of coronary artery disease (CAD).AIM: Present…
Review on the mesenchymal stem cells and their potential application in regenerative medicine Open
Stem cells are unspecialized cells that are capable of self-renewal and differentiate into a variety of cell types. Indeed, stem cells are able to differentiate into functional specialized cells e.g. myocardiocyte, neurocyte, osteoblast, a…
Phytochemistry and insecticidal effect of different parts of Melissa officinalis on Tetranychus urticae Open
Background and objectives: In recent years, biological control of parasites by essential oils (EOs) derived from plants is one of the alternatives to synthetic pesticides.Melissa officinalis from Lamiaceae family is distributed in many par…
Essential oils as natural medicinal substances: review article Open
Herbal essential oils are volatile, natural, complex compounds formed by medicinal plants as secondary metabolites. As reported by international organization for standardization (ISO), the term "essential oils" (EOs) is defined for a produ…