Ehsan Irani
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Active motion of tangentially driven polymers in periodic array of obstacles Open
One key question about transport of active polymers within crowded environments is how spatial order of obstacles influences their conformation and dynamics when compared to disordered media. To this end, we computationally investigate the…
Active motion of tangentially-driven polymers in periodic array of obstacles Open
We computationally investigate the active transport of tangentially-driven polymers with varying degrees of flexibility and activity in two-dimensional square lattices of obstacles. Tight periodic confinement induces notable conformational…
Effects of inertia on conformation and dynamics of tangentially driven active filaments Open
Active filamentlike systems propelling along their backbone exist across scales ranging from motor-driven biofilaments to worms and robotic chains. In macroscopic active filaments such as a chain of robots, in contrast to their microscopic…
Effects of inertia on conformation and dynamics of tangentially-driven active filaments Open
Active filament-like systems propelling along their backbone exist across the scales ranging from motor-driven bio-filaments to worms and robotic chains. In macroscopic active filaments such as chain of robots, in contrast to their microsc…
Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding Open
Loop-extrusion and phase-separation have been proposed as mechanisms that shape chromosome large-scale spatial organization. It is unclear, however, how they perform relative to each other in explaining chromatin architecture data and whet…
Physical mechanisms of chromatin spatial organization Open
In higher eukaryotes, chromosomes have a complex three‐dimensional (3D) conformation in the cell nucleus serving vital functional purposes, yet their folding principles remain poorly understood at the single‐molecule level. Here, we summar…
Cell-type specialization in the brain is encoded by specific long-range chromatin topologies Open
Neurons and oligodendrocytes are terminally differentiated cells that sustain cascades of gene activation and repression to execute highly specialized functions, while retaining homeostatic control. To study long-range chromatin folding wi…
Athermal rheology of weakly attractive soft particles Open
We study the rheology of a soft particulate system where the interparticle interactions are weakly attractive. Using extensive molecular dynamics simulations, we scan across a wide range of packing fractions (ϕ), attraction strengths (u), …
Rheology of Weakly Attractive Soft Particles Open
We study the rheology of a soft particulate system with attractive interactions. Lees-Edwards boundary conditions are used to simulate a shear-controlled flow. Unlike repulsive systems, it is found that in systems with a damping force dire…