Ehsan Nourafkan
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View article: Advancing continuous encapsulation and purification of mRNA vaccines and therapeutics
Advancing continuous encapsulation and purification of mRNA vaccines and therapeutics Open
The messenger RNA (mRNA) platform technology is advancing the deployment of vaccines and therapeutics to combat various diseases. The COVID-19 pandemic highlighted the urgent need for large-scale mRNA vaccine production, exposing supply co…
View article: An Experimental and Modeling Approach to Study Tangential Flow Filtration Performance for mRNA Drug Substance Purification
An Experimental and Modeling Approach to Study Tangential Flow Filtration Performance for mRNA Drug Substance Purification Open
Following the recent COVID‐19 pandemic, mRNA manufacturing processes are being actively developed and optimized to produce the next generation of mRNA vaccines and therapeutics. Herein, the performance of the tangential flow filtration (TF…
View article: Quality by design for mRNA platform purification based on continuous oligo-dT chromatography
Quality by design for mRNA platform purification based on continuous oligo-dT chromatography Open
Oligo-deoxythymidine (oligo-dT) ligand-based affinity chromatography is a robust method for purifying mRNA drug substances within the manufacturing process of mRNA-based products, including vaccines and therapeutics. However, the conventio…
View article: Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development
Anion exchange HPLC monitoring of mRNA in vitro transcription reactions to support mRNA manufacturing process development Open
mRNA technology has recently demonstrated the ability to significantly change the timeline for developing and delivering a new vaccine from years to months. The potential of mRNA technology for rapid vaccine development has recently been h…
View article: Origin of Life from a Maker's Perspective–Focus on Protocellular Compartments in Bottom‐Up Synthetic Biology
Origin of Life from a Maker's Perspective–Focus on Protocellular Compartments in Bottom‐Up Synthetic Biology Open
The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our understandi…
View article: Minimum Surfactant Concentration Required for Inducing Self-shaping of Oil Droplets and Competitive Adsorption Effects
Minimum Surfactant Concentration Required for Inducing Self-shaping of Oil Droplets and Competitive Adsorption Effects Open
Surfactant choice is key in starting the phenomena of artificial morphogenesis, the bottom-up growth of geometric particles from cooled emulsion droplets, as well as the bottom-up self-assembly of rechargeable microswimmer robots from simi…
View article: Origin of life from a maker's perspective -- focus on protocellular compartments in bottom-up synthetic biology
Origin of life from a maker's perspective -- focus on protocellular compartments in bottom-up synthetic biology Open
The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our understandi…
View article: Minimum surfactant concentration required for inducing self-shaping of oil droplets and competitive adsorption effects
Minimum surfactant concentration required for inducing self-shaping of oil droplets and competitive adsorption effects Open
Surfactant above critical micellar concentrations needed for artificial morphogenesis of oil droplets; several surfactant types, salt effects, competitive adsorption investigated.
View article: Improved rheology and high‐temperature stability of hydrolyzed polyacrylamide using graphene oxide nanosheet
Improved rheology and high‐temperature stability of hydrolyzed polyacrylamide using graphene oxide nanosheet Open
Hydrolyzed polyacrylamide (HPAM) is a polymer that extensively used in chemical industry and hydrocarbon extraction and refinery processes, but suffers a common problem of high‐temperature instability. This study improved high‐temperature …
View article: Improved Polymer Flooding in Harsh Environments by Free-Radical Polymerization and the Use of Nanomaterials
Improved Polymer Flooding in Harsh Environments by Free-Radical Polymerization and the Use of Nanomaterials Open
High temperature and high salinity (HTHS) and extreme pH conditions can significantly affect the stability of polymers and deteriorate the performance of polymers in enhanced oil recovery (EOR). This work advances polymer flooding in harsh…
View article: Correction: Hu, Z.; et al. Transport and Deposition of Carbon Nanoparticles in Saturated Porous Media. Energies 2017, 10, 1151
Correction: Hu, Z.; et al. Transport and Deposition of Carbon Nanoparticles in Saturated Porous Media. Energies 2017, 10, 1151 Open
The author wishes to correct Figure 1b in this paper [1][...]
View article: Transport and Deposition of Carbon Nanoparticles in Saturated Porous Media
Transport and Deposition of Carbon Nanoparticles in Saturated Porous Media Open
Carbon nanoparticles (CNPs) are becoming promising candidates for oil/gas applications due to their biocompatibility and size-dependent optical and electronic properties. Their applications, however, are always associated with the flow of …